abnormal foregut morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the anterior portion of the primitive digestive tube of the embryo that lies cephalic to the junction of the yolk stalk, consists of endodermal tissue, and gives rise to the pharynx, lower respiratory system, esophagus, stomach, duodenum proximal to the biliary tract, liver, pancreas, biliary tract, and gall bladder (Mammalian Phenotype Ontology, MP_0000474)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000474
Similar Terms
Downloads & Tools


30 gene mutations causing the abnormal foregut morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APC adenomatous polyposis coli
BMP4 bone morphogenetic protein 4
CRB2 crumbs family member 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FOXA2 forkhead box A2
GATA4 GATA binding protein 4
GLI2 GLI family zinc finger 2
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
LDB1 LIM domain binding 1
MIXL1 Mix paired-like homeobox
NCKAP1 NCK-associated protein 1
NKX2-1 NK2 homeobox 1
NODAL nodal growth differentiation factor
NOG noggin
OTX2 orthodenticle homeobox 2
OVOL2 ovo-like zinc finger 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PDX1 pancreatic and duodenal homeobox 1
PGAP1 post-GPI attachment to proteins 1
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PTK2 protein tyrosine kinase 2
PXN paxillin
SHH sonic hedgehog
SLIT2 slit homolog 2 (Drosophila)
SMAD2 SMAD family member 2
SMAD5 SMAD family member 5
SOX17 SRY (sex determining region Y)-box 17
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TWSG1 twisted gastrulation BMP signaling modulator 1
VCL vinculin