abnormal follicular dendritic cell physiology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description abnormal function of a cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue; follicular dendritic cells have Fc receptors and C3b receptors, and hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response (Mammalian Phenotype Ontology, MP_0008197)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008197
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Genes

4 gene mutations causing the abnormal follicular dendritic cell physiology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CCR6 chemokine (C-C motif) receptor 6
FCAMR Fc receptor, IgA, IgM, high affinity
IGHM immunoglobulin heavy constant mu
TNF tumor necrosis factor