abnormal fatty acid level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the concentration of aliphatic monocarboxylic acids derived from or contained in esterified form in an animal or vegetable fat, oil or wax; natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated (Mammalian Phenotype Ontology, MP_0005280)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005280
Similar Terms
Downloads & Tools

Genes

165 gene mutations causing the abnormal fatty acid level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
ABHD5 abhydrolase domain containing 5
ACACB acetyl-CoA carboxylase beta
ACADL acyl-CoA dehydrogenase, long chain
ACOT11 acyl-CoA thioesterase 11
ACOT13 acyl-CoA thioesterase 13
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSS1 acyl-CoA synthetase short-chain family member 1
ACTB actin, beta
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRA1B adrenoceptor alpha 1B
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AHSG alpha-2-HS-glycoprotein
AMACR alpha-methylacyl-CoA racemase
ANGPTL3 angiopoietin-like 3
ANGPTL6 angiopoietin-like 6
ANKRD26 ankyrin repeat domain 26
APC adenomatous polyposis coli
APOA2 apolipoprotein A-II
BBS12 Bardet-Biedl syndrome 12
BCAT2 branched chain amino-acid transaminase 2, mitochondrial
BCO1 beta-carotene oxygenase 1
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C3 complement component 3
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC120 coiled-coil domain containing 120
CCDC80 coiled-coil domain containing 80
CCL13 chemokine (C-C motif) ligand 13
CD36 CD36 molecule (thrombospondin receptor)
CDH23 cadherin-related 23
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CES1 carboxylesterase 1
CHD7 chromodomain helicase DNA binding protein 7
CIDEA cell death-inducing DFFA-like effector a
CIDEB cell death-inducing DFFA-like effector b
CIDEC cell death-inducing DFFA-like effector c
COQ4 coenzyme Q4
CPT1A carnitine palmitoyltransferase 1A (liver)
CRBN cereblon
CREBBP CREB binding protein
CRHR2 corticotropin releasing hormone receptor 2
CRTC1 CREB regulated transcription coactivator 1
CRTC3 CREB regulated transcription coactivator 3
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTF1 cardiotrophin 1
CYB561 cytochrome b561
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DGAT2 diacylglycerol O-acyltransferase 2
DIXDC1 DIX domain containing 1
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
DNAJC5G DnaJ (Hsp40) homolog, subfamily C, member 5 gamma
DUSP1 dual specificity phosphatase 1
ECI1 enoyl-CoA delta isomerase 1
ELOVL2 ELOVL fatty acid elongase 2
ELOVL4 ELOVL fatty acid elongase 4
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FABP3 fatty acid binding protein 3, muscle and heart
FABP4 fatty acid binding protein 4, adipocyte
FABP7 fatty acid binding protein 7, brain
FADS2 fatty acid desaturase 2
FFAR2 free fatty acid receptor 2
FGF21 fibroblast growth factor 21
FGL1 fibrinogen-like 1
FOXA2 forkhead box A2
FOXO1 forkhead box O1
G0S2 G0/G1 switch 2
GCK glucokinase (hexokinase 4)
GNAS GNAS complex locus
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
HADH hydroxyacyl-CoA dehydrogenase
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HNF4A hepatocyte nuclear factor 4, alpha
HRH1 histamine receptor H1
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
IFT80 intraflagellar transport 80
IL10 interleukin 10
INPP5K inositol polyphosphate-5-phosphatase K
INPPL1 inositol polyphosphate phosphatase-like 1
INSR insulin receptor
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
KDM3A lysine (K)-specific demethylase 3A
KMT2B lysine (K)-specific methyltransferase 2B
LDLR low density lipoprotein receptor
LEPR leptin receptor
LGALS12 lectin, galactoside-binding, soluble, 12
LIPA lipase A, lysosomal acid, cholesterol esterase
LIPE lipase, hormone-sensitive
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPIN1 lipin 1
MBOAT7 membrane bound O-acyltransferase domain containing 7
MC4R melanocortin 4 receptor
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MGLL monoglyceride lipase
MLXIPL MLX interacting protein-like
MTRF1L mitochondrial translational release factor 1-like
MYO7A myosin VIIA
NCOA3 nuclear receptor coactivator 3
NCOR1 nuclear receptor corepressor 1
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
NEU4 sialidase 4
NMU neuromedin U
NOS3 nitric oxide synthase 3 (endothelial cell)
NPY1R neuropeptide Y receptor Y1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NRCAM neuronal cell adhesion molecule
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NUAK2 NUAK family, SNF1-like kinase, 2
OED Oregon eye disease
OSMR oncostatin M receptor
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PEX1 peroxisomal biogenesis factor 1
PEX11A peroxisomal biogenesis factor 11 alpha
PEX2 peroxisomal biogenesis factor 2
PEX7 peroxisomal biogenesis factor 7
PHYH phytanoyl-CoA 2-hydroxylase
PLIN1 perilipin 1
PLIN2 perilipin 2
PLIN5 perilipin 5
PLSCR3 phospholipid scramblase 3
PNPLA2 patatin-like phospholipase domain containing 2
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCI protein kinase C, iota
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PTRF polymerase I and transcript release factor
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RNF7 ring finger protein 7
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCP2 sterol carrier protein 2
SGMS2 sphingomyelin synthase 2
SIRT6 sirtuin 6
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SRA1 steroid receptor RNA activator 1
STARD10 StAR-related lipid transfer (START) domain containing 10
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TBC1D4 TBC1 domain family, member 4
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THEM5 thioesterase superfamily member 5
THRB thyroid hormone receptor, beta
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TXNIP thioredoxin interacting protein
TYK2 tyrosine kinase 2
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
ZEB1 zinc finger E-box binding homeobox 1