abnormal enteric nervous system morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the part of the autonomic nervous system that innervates the gastrointestinal tract, the pancreas, and the gallbladder and can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport (Mammalian Phenotype Ontology, MP_0001044)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001044
Similar Terms
Downloads & Tools


25 gene mutations causing the abnormal enteric nervous system morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ARTN artemin
ASCL1 achaete-scute family bHLH transcription factor 1
ECE1 endothelin converting enzyme 1
EDN3 endothelin 3
EDNRB endothelin receptor type B
ERBB3 erb-b2 receptor tyrosine kinase 3
GDNF glial cell derived neurotrophic factor
GFRA1 GDNF family receptor alpha 1
HLX H2.0-like homeobox
IHH indian hedgehog
KIF26A kinesin family member 26A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
NRTN neurturin
PDS5A PDS5 cohesin associated factor A
PDS5B PDS5 cohesin associated factor B
PHOX2B paired-like homeobox 2b
PSAP prosaposin
RET ret proto-oncogene
SALL4 spalt-like transcription factor 4
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SHH sonic hedgehog
SOX10 SRY (sex determining region Y)-box 10
SPRY2 sprouty homolog 2 (Drosophila)
TLX2 T-cell leukemia homeobox 2
ZIC2 Zic family member 2