abnormal dorsal root ganglion morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of a group of sensory nerve cell bodies located on the dorsal spinal roots within the vertebral column (Mammalian Phenotype Ontology, MP_0000961)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000961
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Genes

80 gene mutations causing the abnormal dorsal root ganglion morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CD86 CD86 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DLL1 delta-like 1 (Drosophila)
DLL3 delta-like 3 (Drosophila)
DOCK3 dedicator of cytokinesis 3
DST dystonin
EGFR epidermal growth factor receptor
EGR3 early growth response 3
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ETV1 ets variant 1
FKBP8 FK506 binding protein 8, 38kDa
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GAL galanin/GMAP prepropeptide
GALR2 galanin receptor 2
GBX1 gastrulation brain homeobox 1
GDF15 growth differentiation factor 15
GDNF glial cell derived neurotrophic factor
GLRB glycine receptor, beta
HOXB13 homeobox B13
HOXB8 homeobox B8
HRK harakiri, BCL2 interacting protein
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2
KIFAP3 kinesin-associated protein 3
KMT2A lysine (K)-specific methyltransferase 2A
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LGALS1 lectin, galactoside-binding, soluble, 1
LIFR leukemia inhibitory factor receptor alpha
LRP6 low density lipoprotein receptor-related protein 6
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MSGN1 mesogenin 1
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NDN necdin, melanoma antigen (MAGE) family member
NEUROG2 neurogenin 2
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOTO notochord homeobox
NPR2 natriuretic peptide receptor 2
NRARP NOTCH-regulated ankyrin repeat protein
NRG1 neuregulin 1
NRP1 neuropilin 1
NTF3 neurotrophin 3
NTF4 neurotrophin 4
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUMB numb homolog (Drosophila)
OLIG2 oligodendrocyte lineage transcription factor 2
OSM oncostatin M
PAX3 paired box 3
PDPK1 3-phosphoinositide dependent protein kinase 1
PIKFYVE phosphoinositide kinase, FYVE finger containing
PMP22 peripheral myelin protein 22
POU4F1 POU class 4 homeobox 1
PSAP prosaposin
PSEN1 presenilin 1
RAB23 RAB23, member RAS oncogene family
RB1 retinoblastoma 1
RUNX3 runt-related transcription factor 3
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SOX10 SRY (sex determining region Y)-box 10
TBX18 T-box 18
TCOF1 Treacher Collins-Franceschetti syndrome 1
TRAF4 TNF receptor-associated factor 4
TULP3 tubby like protein 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UNCX UNC homeobox
VAC14 Vac14 homolog (S. cerevisiae)
VCL vinculin
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZIC2 Zic family member 2