abnormal dendritic cell differentiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description atypical production of or inability to produce a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation (Mammalian Phenotype Ontology, MP_0008115)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008115
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Genes

14 gene mutations causing the abnormal dendritic cell differentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AZI2 5-azacytidine induced 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
IL13 interleukin 13
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
JAK3 Janus kinase 3
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MYD88 myeloid differentiation primary response 88
RUNX3 runt-related transcription factor 3
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor