abnormal dendritic cell antigen presentation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the ability of dendritic cells to process and present antigen to T lymphocytes (Mammalian Phenotype Ontology, MP_0002455)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002455
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Genes

32 gene mutations causing the abnormal dendritic cell antigen presentation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BATF3 basic leucine zipper transcription factor, ATF-like 3
CD1D CD1d molecule
CD68 CD68 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CLEC9A C-type lectin domain family 9, member A
CTSE cathepsin E
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FLT3 fms-related tyrosine kinase 3
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IFNG interferon, gamma
IL13 interleukin 13
IL4 interleukin 4
IL6ST interleukin 6 signal transducer
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
PDCD1LG2 programmed cell death 1 ligand 2
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SKAP2 src kinase associated phosphoprotein 2
SYK spleen tyrosine kinase
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
UNC93B1 unc-93 homolog B1 (C. elegans)
WAS Wiskott-Aldrich syndrome