abnormal dendrite morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body (Mammalian Phenotype Ontology, MP_0008143)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008143
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106 gene mutations causing the abnormal dendrite morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACP2 acid phosphatase 2, lysosomal
ACTL6B actin-like 6B
AGTPBP1 ATP/GTP binding protein 1
APOE apolipoprotein E
ARCN1 archain 1
ARF4 ADP-ribosylation factor 4
ARHGAP33 Rho GTPase activating protein 33
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ATM ATM serine/threonine kinase
ATXN1 ataxin 1
BCL2L2 BCL2-like 2
BDNF brain-derived neurotrophic factor
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CADPS2 Ca++-dependent secretion activator 2
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPRIN1 cell cycle associated protein 1
CAV1 caveolin 1, caveolae protein, 22kDa
CC2D1A coiled-coil and C2 domain containing 1A
CCND2 cyclin D2
CD47 CD47 molecule
CEND1 cell cycle exit and neuronal differentiation 1
CERS1 ceramide synthase 1
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
CNTN1 contactin 1
COQ9 coenzyme Q9
CPEB3 cytoplasmic polyadenylation element binding protein 3
CPEB4 cytoplasmic polyadenylation element binding protein 4
CPT1C carnitine palmitoyltransferase 1C
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAB2IP DAB2 interacting protein
DACT1 dishevelled-binding antagonist of beta-catenin 1
DGCR8 DGCR8 microprocessor complex subunit
DLG4 discs, large homolog 4 (Drosophila)
DNM1 dynamin 1
DPYSL2 dihydropyrimidinase-like 2
DPYSL5 dihydropyrimidinase-like 5
DUSP1 dual specificity phosphatase 1
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF4H eukaryotic translation initiation factor 4H
FMR1 fragile X mental retardation 1
FOXO6 forkhead box O6
FOXP2 forkhead box P2
GAS1 growth arrest-specific 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRID2 glutamate receptor, ionotropic, delta 2
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRN granulin
HOMER1 homer scaffolding protein 1
KALRN kalirin, RhoGEF kinase
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KIDINS220 kinase D-interacting substrate, 220kDa
KIF14 kinesin family member 14
LRRK2 leucine-rich repeat kinase 2
LRRTM1 leucine rich repeat transmembrane neuronal 1
MAP1B microtubule-associated protein 1B
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAPT microtubule-associated protein tau
MCF2 MCF.2 cell line derived transforming sequence
MECP2 methyl CpG binding protein 2
MYH10 myosin, heavy chain 10, non-muscle
MYO5A myosin VA (heavy chain 12, myoxin)
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NENF neudesin neurotrophic factor
NOS1 nitric oxide synthase 1 (neuronal)
NR1D1 nuclear receptor subfamily 1, group D, member 1
NRN1 neuritin 1
NRP2 neuropilin 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPHN1 oligophrenin 1
OTC ornithine carbamoyltransferase
PLXNA2 plexin A2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTEN phosphatase and tensin homolog
RORA RAR-related orphan receptor A
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SCYL1 SCY1-like 1 (S. cerevisiae)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEPT7 septin 7
SEZ6 seizure related 6 homolog (mouse)
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPTBN2 spectrin, beta, non-erythrocytic 2
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STAU1 staufen double-stranded RNA binding protein 1
STK38L serine/threonine kinase 38 like
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYNGAP1 synaptic Ras GTPase activating protein 1
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
TOR1A torsin family 1, member A (torsin A)
TP73 tumor protein p73
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TUBA1A tubulin, alpha 1a
UBE3A ubiquitin protein ligase E3A
VIM vimentin
ZNF423 zinc finger protein 423