abnormal cytokine secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the production or cellular release of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells (Mammalian Phenotype Ontology, MP_0003009)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003009
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Genes

514 gene mutations causing the abnormal cytokine secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACKR4 atypical chemokine receptor 4
ACP1 acid phosphatase 1, soluble
ADAM17 ADAM metallopeptidase domain 17
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADORA3 adenosine A3 receptor
ADRB2 adrenoceptor beta 2, surface
AGER advanced glycosylation end product-specific receptor
AHNAK AHNAK nucleoprotein
AHR aryl hydrocarbon receptor
AIM2 absent in melanoma 2
AIRE autoimmune regulator
ANXA5 annexin A5
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APOE apolipoprotein E
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARRB2 arrestin, beta 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATF2 activating transcription factor 2
ATF3 activating transcription factor 3
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG9A autophagy related 9A
AZI2 5-azacytidine induced 2
B2M beta-2-microglobulin
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BAG4 BCL2-associated athanogene 4
BATF basic leucine zipper transcription factor, ATF-like
BCL10 B-cell CLL/lymphoma 10
BCL2L1 BCL2-like 1
BCL3 B-cell CLL/lymphoma 3
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BPIFA1 BPI fold containing family A, member 1
BTLA B and T lymphocyte associated
C3AR1 complement component 3a receptor 1
CABIN1 calcineurin binding protein 1
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CADM1 cell adhesion molecule 1
CARD11 caspase recruitment domain family, member 11
CARD9 caspase recruitment domain family, member 9
CASP12 caspase 12 (gene/pseudogene)
CASP4 caspase 4, apoptosis-related cysteine peptidase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CC2D1A coiled-coil and C2 domain containing 1A
CCAR2 cell cycle and apoptosis regulator 2
CCL13 chemokine (C-C motif) ligand 13
CCL5 chemokine (C-C motif) ligand 5
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CCRL2 chemokine (C-C motif) receptor-like 2
CD14 CD14 molecule
CD19 CD19 molecule
CD1D CD1d molecule
CD200R1 CD200 receptor 1
CD247 CD247 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD28 CD28 molecule
CD300A CD300a molecule
CD300LF CD300 molecule-like family member f
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CD69 CD69 molecule
CD7 CD7 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD84 CD84 molecule
CD86 CD86 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIITA class II, major histocompatibility complex, transactivator
CISH cytokine inducible SH2-containing protein
CLEC10A C-type lectin domain family 10, member A
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CLEC4F C-type lectin domain family 4, member F
CLEC6A C-type lectin domain family 6, member A
CLEC7A C-type lectin domain family 7, member A
CLIC4 chloride intracellular channel 4
CLNK cytokine-dependent hematopoietic cell linker
CNPY3 canopy FGF signaling regulator 3
COMT catechol-O-methyltransferase
CORO1A coronin, actin binding protein, 1A
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRH corticotropin releasing hormone
CRLF2 cytokine receptor-like factor 2
CRTAM cytotoxic and regulatory T cell molecule
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSE cathepsin E
CTSS cathepsin S
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2 chemokine (C-X-C motif) receptor 2
DBNL drebrin-like
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGKA diacylglycerol kinase, alpha 80kDa
DGKZ diacylglycerol kinase, zeta
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DMD dystrophin
DRD2 dopamine receptor D2
DTX1 deltex 1, E3 ubiquitin ligase
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP2 dual specificity phosphatase 2
DUSP4 dual specificity phosphatase 4
E2F1 E2F transcription factor 1
EBI3 Epstein-Barr virus induced 3
EFS embryonal Fyn-associated substrate
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EPHB6 EPH receptor B6
ERAP1 endoplasmic reticulum aminopeptidase 1
F3 coagulation factor III (thromboplastin, tissue factor)
FADS1 fatty acid desaturase 1
FAS Fas cell surface death receptor
FASTK Fas-activated serine/threonine kinase
FBN1 fibrillin 1
FBXO11 F-box protein 11
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCMR Fc fragment of IgM receptor
FFAR2 free fatty acid receptor 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FLG filaggrin
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXN1 forkhead box N1
FOXP3 forkhead box P3
FPR2 formyl peptide receptor 2
FYB FYN binding protein
FYN FYN proto-oncogene, Src family tyrosine kinase
G6PC2 glucose-6-phosphatase, catalytic, 2
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GATA3 GATA binding protein 3
GBP5 guanylate binding protein 5
GFI1 growth factor independent 1 transcription repressor
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GPR15 G protein-coupled receptor 15
GPR34 G protein-coupled receptor 34
GPR65 G protein-coupled receptor 65
GPR84 G protein-coupled receptor 84
GRN granulin
HAVCR1 hepatitis A virus cellular receptor 1
HAVCR2 hepatitis A virus cellular receptor 2
HCK HCK proto-oncogene, Src family tyrosine kinase
HCST hematopoietic cell signal transducer
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-G major histocompatibility complex, class I, G
HPGDS hematopoietic prostaglandin D synthase
HRH1 histamine receptor H1
HSF1 heat shock transcription factor 1
HSH2D hematopoietic SH2 domain containing
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1B heat shock 70kDa protein 1B
HSPB1 heat shock 27kDa protein 1
ICOS inducible T-cell co-stimulator
ICOSLG inducible T-cell co-stimulator ligand
IDO1 indoleamine 2,3-dioxygenase 1
IDO2 indoleamine 2,3-dioxygenase 2
IER3 immediate early response 3
IFIH1 interferon induced with helicase C domain 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGHM immunoglobulin heavy constant mu
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL13 interleukin 13
IL13RA2 interleukin 13 receptor, alpha 2
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL17C interleukin 17C
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL17RB interleukin 17 receptor B
IL17RC interleukin 17 receptor C
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL18RAP interleukin 18 receptor accessory protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL1RAP interleukin 1 receptor accessory protein
IL1RL1 interleukin 1 receptor-like 1
IL1RL2 interleukin 1 receptor-like 2
IL1RN interleukin 1 receptor antagonist
IL20RB interleukin 20 receptor beta
IL21R interleukin 21 receptor
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL25 interleukin 25
IL27 interleukin 27
IL27RA interleukin 27 receptor, alpha
IL2RG interleukin 2 receptor, gamma
IL33 interleukin 33
IL34 interleukin 34
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IL9 interleukin 9
ING4 inhibitor of growth family, member 4
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
IRF5 interferon regulatory factor 5
IRF7 interferon regulatory factor 7
IRF8 interferon regulatory factor 8
IRF9 interferon regulatory factor 9
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITK IL2-inducible T-cell kinase
JAK3 Janus kinase 3
KHSRP KH-type splicing regulatory protein
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT1 keratin 1, type II
LAPTM5 lysosomal protein transmembrane 5
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LBP lipopolysaccharide binding protein
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LECT2 leukocyte cell-derived chemotaxin 2
LEP leptin
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGMN legumain
LIF leukemia inhibitory factor
LIG4 ligase IV, DNA, ATP-dependent
LITAF lipopolysaccharide-induced TNF factor
LPAR2 lysophosphatidic acid receptor 2
LTA lymphotoxin alpha
LTB4R leukotriene B4 receptor
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LY9 lymphocyte antigen 9
LY96 lymphocyte antigen 96
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MALT1 MALT1 paracaspase
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
MARCO macrophage receptor with collagenous structure
MARK2 MAP/microtubule affinity-regulating kinase 2
MAVS mitochondrial antiviral signaling protein
MBP myelin basic protein
MBTPS1 membrane-bound transcription factor peptidase, site 1
MEFV Mediterranean fever
MERTK MER proto-oncogene, tyrosine kinase
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR155 microRNA 155
MMP1 matrix metallopeptidase 1
MMP28 matrix metallopeptidase 28
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MOG myelin oligodendrocyte glycoprotein
MPZ myelin protein zero
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MSR1 macrophage scavenger receptor 1
MST1R macrophage stimulating 1 receptor
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYD88 myeloid differentiation primary response 88
MYO1G myosin IG
NAMPT nicotinamide phosphoribosyltransferase
NCKAP1L NCK-associated protein 1-like
NCOA3 nuclear receptor coactivator 3
NDFIP1 Nedd4 family interacting protein 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
NFIL3 nuclear factor, interleukin 3 regulated
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NLRC3 NLR family, CARD domain containing 3
NLRC4 NLR family, CARD domain containing 4
NLRC5 NLR family, CARD domain containing 5
NLRP1 NLR family, pyrin domain containing 1
NLRP10 NLR family, pyrin domain containing 10
NLRP3 NLR family, pyrin domain containing 3
NLRP6 NLR family, pyrin domain containing 6
NLRX1 NLR family member X1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NPY1R neuropeptide Y receptor Y1
ORAI1 ORAI calcium release-activated calcium modulator 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PBK PDZ binding kinase
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM2 PDZ and LIM domain 2 (mystique)
PECAM1 platelet/endothelial cell adhesion molecule 1
PELI1 pellino E3 ubiquitin protein ligase 1
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PGR progesterone receptor
PIGR polymeric immunoglobulin receptor
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PILRB paired immunoglobin-like type 2 receptor beta
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PINK1 PTEN induced putative kinase 1
PLA2G2D phospholipase A2, group IID
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POMC proopiomelanocortin
POU2AF1 POU class 2 associating factor 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRF1 perforin 1 (pore forming protein)
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCQ protein kinase C, theta
PRKD2 protein kinase D2
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTGDR2 prostaglandin D2 receptor 2
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PYCARD PYD and CARD domain containing
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAD50 RAD50 homolog (S. cerevisiae)
RAG2 recombination activating gene 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAP1A RAP1A, member of RAS oncogene family
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RC3H2 ring finger and CCCH-type domains 2
RCAN1 regulator of calcineurin 1
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RETNLB resistin like beta
RFTN1 raftlin, lipid raft linker 1
RGS16 regulator of G-protein signaling 16
RHBDD3 rhomboid domain containing 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIPK2 receptor-interacting serine-threonine kinase 2
RLTPR RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF19B ring finger protein 19B
RORA RAR-related orphan receptor A
RSAD2 radical S-adenosyl methionine domain containing 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SASH3 SAM and SH3 domain containing 3
SCTR secretin receptor
SDC1 syndecan 1
SELK selenoprotein K
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SH2D1A SH2 domain containing 1A
SH2D1B SH2 domain containing 1B
SH2D2A SH2 domain containing 2A
SH2D3C SH2 domain containing 3C
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SIRT7 sirtuin 7
SIT1 signaling threshold regulating transmembrane adaptor 1
SKAP1 src kinase associated phosphoprotein 1
SLAMF1 signaling lymphocytic activation molecule family member 1
SLAMF6 SLAM family member 6
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SMAD3 SMAD family member 3
SOCS1 suppressor of cytokine signaling 1
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOD3 superoxide dismutase 3, extracellular
SPP1 secreted phosphoprotein 1
SPRED1 sprouty-related, EVH1 domain containing 1
SQSTM1 sequestosome 1
SSTR4 somatostatin receptor 4
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT4 signal transducer and activator of transcription 4
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STIM1 stromal interaction molecule 1
STK17B serine/threonine kinase 17b
STK4 serine/threonine kinase 4
STX11 syntaxin 11
SUCNR1 succinate receptor 1
SYK spleen tyrosine kinase
TANK TRAF family member-associated NFKB activator
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBK1 TANK-binding kinase 1
TBX21 T-box 21
TESPA1 thymocyte expressed, positive selection associated 1
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
TICAM1 toll-like receptor adaptor molecule 1
TICAM2 toll-like receptor adaptor molecule 2
TIGIT T cell immunoreceptor with Ig and ITIM domains
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TIMP3 TIMP metallopeptidase inhibitor 3
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNIP1 TNFAIP3 interacting protein 1
TOLLIP toll interacting protein
TRADD TNFRSF1A-associated via death domain
TRAF3IP2 TRAF3 interacting protein 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAFD1 TRAF-type zinc finger domain containing 1
TREML1 triggering receptor expressed on myeloid cells-like 1
TRIB1 tribbles pseudokinase 1
TRIM27 tripartite motif containing 27
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC22D3 TSC22 domain family, member 3
TSLP thymic stromal lymphopoietin
TUSC2 tumor suppressor candidate 2
TXK TXK tyrosine kinase
TYK2 tyrosine kinase 2
TYROBP TYRO protein tyrosine kinase binding protein
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UNC13D unc-13 homolog D (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
USP18 ubiquitin specific peptidase 18
USP25 ubiquitin specific peptidase 25
VAV1 vav 1 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIPR2 vasoactive intestinal peptide receptor 2
VTCN1 V-set domain containing T cell activation inhibitor 1
WAS Wiskott-Aldrich syndrome
XCR1 chemokine (C motif) receptor 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB32 zinc finger and BTB domain containing 32
ZBTB7B zinc finger and BTB domain containing 7B
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H12D zinc finger CCCH-type containing 12D