abnormal circulating pituitary hormone level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description aberration in the blood concentration of any of the hormones secreted by the pituitary (Mammalian Phenotype Ontology, MP_0005116)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005116
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Genes

131 gene mutations causing the abnormal circulating pituitary hormone level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVR2A activin A receptor, type IIA
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADRA1B adrenoceptor alpha 1B
ADRM1 adhesion regulating molecule 1
AFP alpha-fetoprotein
AGTR2 angiotensin II receptor, type 2
AMH anti-Mullerian hormone
AR androgen receptor
ASIP agouti signaling protein
AVPR1B arginine vasopressin receptor 1B
BCL2L2 BCL2-like 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BRS3 bombesin-like receptor 3
CDK4 cyclin-dependent kinase 4
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CGA glycoprotein hormones, alpha polypeptide
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
CORT cortistatin
CPE carboxypeptidase E
CRTC1 CREB regulated transcription coactivator 1
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DHH desert hedgehog
DIO2 deiodinase, iodothyronine, type II
DIO3 deiodinase, iodothyronine, type III
DRD2 dopamine receptor D2
DUOX2 dual oxidase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FANCL Fanconi anemia, complementation group L
FGF21 fibroblast growth factor 21
FOXA1 forkhead box A1
FOXE1 forkhead box E1
FOXN1 forkhead box N1
FOXO3 forkhead box O3
FSHB follicle stimulating hormone, beta polypeptide
FSHR follicle stimulating hormone receptor
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GDF9 growth differentiation factor 9
GHR growth hormone receptor
GHRHR growth hormone releasing hormone receptor
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
GPR3 G protein-coupled receptor 3
GRID2 glutamate receptor, ionotropic, delta 2
HMX2 H6 family homeobox 2
HMX3 H6 family homeobox 3
HNF1A HNF1 homeobox A
HOXA5 homeobox A5
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
INHA inhibin, alpha
INHBA inhibin, beta A
INHBB inhibin, beta B
IRS2 insulin receptor substrate 2
JUND jun D proto-oncogene
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAMA2 laminin, alpha 2
LATS1 large tumor suppressor kinase 1
LHCGR luteinizing hormone/choriogonadotropin receptor
LHX3 LIM homeobox 3
LHX9 LIM homeobox 9
LIF leukemia inhibitory factor
LIN28A lin-28 homolog A (C. elegans)
LMNA lamin A/C
MARK2 MAP/microtubule affinity-regulating kinase 2
MBOAT4 membrane bound O-acyltransferase domain containing 4
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MEX3C mex-3 RNA binding family member C
MRC1 mannose receptor, C type 1
NCOA1 nuclear receptor coactivator 1
NHLH2 nescient helix loop helix 2
NKX2-1 NK2 homeobox 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NPC1 Niemann-Pick disease, type C1
NPEPPS aminopeptidase puromycin sensitive
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OTX2 orthodenticle homeobox 2
PAX6 paired box 6
PAX8 paired box 8
PCSK1 proprotein convertase subtilisin/kexin type 1
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PDE8B phosphodiesterase 8B
PGR progesterone receptor
PLK4 polo-like kinase 4
POMC proopiomelanocortin
POU1F1 POU class 1 homeobox 1
PRL prolactin
PRLR prolactin receptor
PROP1 PROP paired-like homeobox 1
PSEN1 presenilin 1
PTDSS2 phosphatidylserine synthase 2
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RIMS2 regulating synaptic membrane exocytosis 2
SERP1 stress-associated endoplasmic reticulum protein 1
SIRT1 sirtuin 1
SIX5 SIX homeobox 5
SOCS2 suppressor of cytokine signaling 2
SOD1 superoxide dismutase 1, soluble
SST somatostatin
SSTR2 somatostatin receptor 2
STAT5B signal transducer and activator of transcription 5B
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBX19 T-box 19
TG thyroglobulin
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TLR2 toll-like receptor 2
TPO thyroid peroxidase
TRH thyrotropin-releasing hormone
TRHR thyrotropin-releasing hormone receptor
TSHR thyroid stimulating hormone receptor
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1
UCN2 urocortin 2
UTP14C UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VGF VGF nerve growth factor inducible
VIP vasoactive intestinal peptide
XPA xeroderma pigmentosum, complementation group A
ZMPSTE24 zinc metallopeptidase STE24