abnormal circulating lactate dehydrogenase level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description abnormal blood level of the tetrameric enzyme that, along with the coenzyme NAD+, catalyzes the interconversion of lactate and pyruvate; measurements of circulating levels are used clinically as a diagnostic indicator of tissue breakdown, some forms of cancer or particular infection types (Mammalian Phenotype Ontology, MP_0011970)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011970
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Genes

5 gene mutations causing the abnormal circulating lactate dehydrogenase level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
GPRC5C G protein-coupled receptor, class C, group 5, member C
PRF1 perforin 1 (pore forming protein)
RAB27A RAB27A, member RAS oncogene family
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
STX11 syntaxin 11