abnormal circulating glucagon level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the blood concentration of the peptide hormone secreted by the alpha cells of the pancreas that normally plays an important role in regulation of blood glucose concentration, ketone metabolism, and several other biochemical and physiological processes (Mammalian Phenotype Ontology, MP_0002695)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002695
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Genes

34 gene mutations causing the abnormal circulating glucagon level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BRD2 bromodomain containing 2
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CHRM3 cholinergic receptor, muscarinic 3
CREBBP CREB binding protein
CRH corticotropin releasing hormone
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DPP4 dipeptidyl-peptidase 4
FFAR1 free fatty acid receptor 1
FOXA1 forkhead box A1
FTO fat mass and obesity associated
G6PC3 glucose 6 phosphatase, catalytic, 3
GCGR glucagon receptor
GHR growth hormone receptor
GNAS GNAS complex locus
GPER1 G protein-coupled estrogen receptor 1
GPR68 G protein-coupled receptor 68
KLF15 Kruppel-like factor 15
LEPR leptin receptor
MIR375 microRNA 375
NCOA3 nuclear receptor coactivator 3
NQO1 NAD(P)H dehydrogenase, quinone 1
ONECUT1 one cut homeobox 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PDYN prodynorphin
PITPNA phosphatidylinositol transfer protein, alpha
PROX1 prospero homeobox 1
RIMS2 regulating synaptic membrane exocytosis 2
SCG5 secretogranin V
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SSTR5 somatostatin receptor 5
THRA thyroid hormone receptor, alpha
ZBTB20 zinc finger and BTB domain containing 20