abnormal circulating chemokine level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description deviation from the normal levels of any of the class of pro-inflammatory cytokines that attract and activate leukocytes in the circulation (Mammalian Phenotype Ontology, MP_0010209)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010209
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Genes

16 gene mutations causing the abnormal circulating chemokine level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACKR4 atypical chemokine receptor 4
CCR1 chemokine (C-C motif) receptor 1
CD44 CD44 molecule (Indian blood group)
CXCL6 chemokine (C-X-C motif) ligand 6
GPR21 G protein-coupled receptor 21
IFNGR1 interferon gamma receptor 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MPL MPL proto-oncogene, thrombopoietin receptor
NLRP3 NLR family, pyrin domain containing 3
PGLYRP2 peptidoglycan recognition protein 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
SELK selenoprotein K
TNF tumor necrosis factor
ZC3H12A zinc finger CCCH-type containing 12A
ZFPM1 zinc finger protein, FOG family member 1