abnormal chemical nociception Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description abnormal capability to sense pain elicited by chemical stimulation (Mammalian Phenotype Ontology, MP_0002735)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002735
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Genes

36 gene mutations causing the abnormal chemical nociception phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADCY1 adenylate cyclase 1 (brain)
ADCY8 adenylate cyclase 8 (brain)
ASIC3 acid sensing (proton gated) ion channel 3
BAMBI BMP and activin membrane-bound inhibitor
BHLHE22 basic helix-loop-helix family, member e22
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CALCB calcitonin-related polypeptide beta
CNR1 cannabinoid receptor 1 (brain)
ESR2 estrogen receptor 2 (ER beta)
FAAH fatty acid amide hydrolase
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIK1 glutamate receptor, ionotropic, kainate 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
HDC histidine decarboxylase
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNIP3 Kv channel interacting protein 3, calsenilin
NMUR2 neuromedin U receptor 2
OPRL1 opiate receptor-like 1
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
PIRT phosphoinositide-interacting regulator of transient receptor potential channels
PITX3 paired-like homeodomain 3
POMK protein-O-mannose kinase
PROKR1 prokineticin receptor 1
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
TACR1 tachykinin receptor 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4