abnormal cerebellar molecular layer Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the outermost layer of the cerebral cortex that contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells (Mammalian Phenotype Ontology, MP_0000889)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000889
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Genes

40 gene mutations causing the abnormal cerebellar molecular layer phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACP2 acid phosphatase 2, lysosomal
AFF1 AF4/FMR2 family, member 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARSA arylsulfatase A
ATM ATM serine/threonine kinase
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CCR10 chemokine (C-C motif) receptor 10
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEND1 cell cycle exit and neuronal differentiation 1
CNTN1 contactin 1
CNTNAP1 contactin associated protein 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
FOXP2 forkhead box P2
GAS1 growth arrest-specific 1
GM2A GM2 ganglioside activator
GPR37L1 G protein-coupled receptor 37 like 1
GRID2 glutamate receptor, ionotropic, delta 2
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KLHL1 kelch-like family member 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MYH10 myosin, heavy chain 10, non-muscle
NEUROD4 neuronal differentiation 4
NFIA nuclear factor I/A
NR1D1 nuclear receptor subfamily 1, group D, member 1
PLXNA2 plexin A2
PRNP prion protein
PTCH1 patched 1
PURA purine-rich element binding protein A
RORA RAR-related orphan receptor A
SKOR2 SKI family transcriptional corepressor 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SPTBN2 spectrin, beta, non-erythrocytic 2
THRB thyroid hormone receptor, beta
UNC5C unc-5 homolog C (C. elegans)