abnormal cellular extravasation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the migration of leukocytes from the blood vessels into the surrounding tissue (Mammalian Phenotype Ontology, MP_0009858)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009858
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Genes

42 gene mutations causing the abnormal cellular extravasation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ADORA2B adenosine A2b receptor
AOC3 amine oxidase, copper containing 3
ARNTL aryl hydrocarbon receptor nuclear translocator-like
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD44 CD44 molecule (Indian blood group)
CDH5 cadherin 5, type 2 (vascular endothelium)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CTTN cortactin
CXCR3 chemokine (C-X-C motif) receptor 3
CYTIP cytohesin 1 interacting protein
EDIL3 EGF-like repeats and discoidin I-like domains 3
ESAM endothelial cell adhesion molecule
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
ICAM1 intercellular adhesion molecule 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB7 integrin, beta 7
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LSP1 lymphocyte-specific protein 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
S100A9 S100 calcium binding protein A9
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
TLR2 toll-like receptor 2
VIM vimentin