abnormal cell chemotaxis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the directed movement of a motile cell guided by a specific chemical concentration gradient; movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis) (Mammalian Phenotype Ontology, MP_0011518)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011518
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Genes

100 gene mutations causing the abnormal cell chemotaxis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACTN4 actinin, alpha 4
AGER advanced glycosylation end product-specific receptor
ALOX5 arachidonate 5-lipoxygenase
ANGPTL2 angiopoietin-like 2
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
CAMP cathelicidin antimicrobial peptide
CAPG capping protein (actin filament), gelsolin-like
CAV1 caveolin 1, caveolae protein, 22kDa
CCL13 chemokine (C-C motif) ligand 13
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCRL2 chemokine (C-C motif) receptor-like 2
CD36 CD36 molecule (thrombospondin receptor)
CD47 CD47 molecule
CD69 CD69 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CMKLR1 chemerin chemokine-like receptor 1
CNN2 calponin 2
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3R colony stimulating factor 3 receptor (granulocyte)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
DOCK2 dedicator of cytokinesis 2
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FFAR2 free fatty acid receptor 2
FLOT1 flotillin 1
FLT1 fms-related tyrosine kinase 1
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FSCN1 fascin actin-bundling protein 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLB1 galactosidase, beta 1
GPR132 G protein-coupled receptor 132
GSN gelsolin
IFNG interferon, gamma
IL18 interleukin 18
IL1R1 interleukin 1 receptor, type I
IL4R interleukin 4 receptor
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JMJD6 jumonji domain containing 6
LGALS3 lectin, galactoside-binding, soluble, 3
LITAF lipopolysaccharide-induced TNF factor
LSP1 lymphocyte-specific protein 1
LTB4R leukotriene B4 receptor
LTB4R2 leukotriene B4 receptor 2
MARCO macrophage receptor with collagenous structure
MDK midkine (neurite growth-promoting factor 2)
MMP28 matrix metallopeptidase 28
MMP7 matrix metallopeptidase 7
MPP1 membrane protein, palmitoylated 1, 55kDa
MPZ myelin protein zero
MYO1F myosin IF
MYO9B myosin IXB
NCKAP1L NCK-associated protein 1-like
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NINJ1 ninjurin 1
NLRP12 NLR family, pyrin domain containing 12
NPR1 natriuretic peptide receptor 1
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLA2G10 phospholipase A2, group X
PLAU plasminogen activator, urokinase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEC plectin
PON2 paraoxonase 2
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PTGES prostaglandin E synthase
PTK2B protein tyrosine kinase 2 beta
PTN pleiotrophin
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RASGRP4 RAS guanyl releasing protein 4
REL v-rel avian reticuloendotheliosis viral oncogene homolog
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
S100A4 S100 calcium binding protein A4
SELK selenoprotein K
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SMAD3 SMAD family member 3
SPP1 secreted phosphoprotein 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TLR4 toll-like receptor 4
TPSAB1 tryptase alpha/beta 1
TRAF3IP2 TRAF3 interacting protein 2
TRPV2 transient receptor potential cation channel, subfamily V, member 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WASL Wiskott-Aldrich syndrome-like
WDR1 WD repeat domain 1