abnormal cd4-positive helper t cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of a CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions (Mammalian Phenotype Ontology, MP_0010183)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010183
Similar Terms
Downloads & Tools

Genes

80 gene mutations causing the abnormal cd4-positive helper t cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACKR4 atypical chemokine receptor 4
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
APOE apolipoprotein E
ARID5A AT rich interactive domain 5A (MRF1-like)
B2M beta-2-microglobulin
BATF basic leucine zipper transcription factor, ATF-like
BCL6 B-cell CLL/lymphoma 6
BHLHE41 basic helix-loop-helix family, member e41
C3AR1 complement component 3a receptor 1
CARD11 caspase recruitment domain family, member 11
CD247 CD247 molecule
CD274 CD274 molecule
CD5 CD5 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CISH cytokine inducible SH2-containing protein
CLEC10A C-type lectin domain family 10, member A
EBI3 Epstein-Barr virus induced 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FBN1 fibrillin 1
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2
ICOSLG inducible T-cell co-stimulator ligand
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IL13 interleukin 13
IL13RA1 interleukin 13 receptor, alpha 1
IL17RA interleukin 17 receptor A
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IL9R interleukin 9 receptor
IRF1 interferon regulatory factor 1
IRF4 interferon regulatory factor 4
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
LAT linker for activation of T cells
LGALS9B lectin, galactoside-binding, soluble, 9B
LY9 lymphocyte antigen 9
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MIR155 microRNA 155
MMP9 matrix metallopeptidase 9
NDFIP1 Nedd4 family interacting protein 1
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NLRP3 NLR family, pyrin domain containing 3
PCSK1 proprotein convertase subtilisin/kexin type 1
PDCD1 programmed cell death 1
PGAP3 post-GPI attachment to proteins 3
PNP purine nucleoside phosphorylase
POLB polymerase (DNA directed), beta
PRKCQ protein kinase C, theta
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RC3H1 ring finger and CCCH-type domains 1
REG3G regenerating islet-derived 3 gamma
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RSAD2 radical S-adenosyl methionine domain containing 2
RXRA retinoid X receptor, alpha
SCARF1 scavenger receptor class F, member 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH2D1A SH2 domain containing 1A
SIT1 signaling threshold regulating transmembrane adaptor 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBX21 T-box 21
TGFB1 transforming growth factor, beta 1
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TNIP1 TNFAIP3 interacting protein 1
TSLP thymic stromal lymphopoietin
UNC93B1 unc-93 homolog B1 (C. elegans)
VTCN1 V-set domain containing T cell activation inhibitor 1
ZC3H12D zinc finger CCCH-type containing 12D