abnormal bone structure Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Any anomaly in the composite material or the layered arrangement of the bony skeleton. (Human Phenotype Ontology, HP_0003330)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0003330
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Genes

593 genes associated with the abnormal bone structure phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
HLA-DRA major histocompatibility complex, class II, DR alpha 3.29256
IL23R interleukin 23 receptor 2.56143
STAT4 signal transducer and activator of transcription 4 2.29928
C6ORF10 chromosome 6 open reading frame 10 2.25073
LPP LIM domain containing preferred translocation partner in lipoma 2.24916
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.11213
NOTCH4 notch 4 2.1091
TNXB tenascin XB 2.0497
KIAA1109 KIAA1109 2.0255
OTUD3 OTU deubiquitinase 3 1.84261
ATXN2 ataxin 2 1.80407
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.77653
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.77521
ERBB3 erb-b2 receptor tyrosine kinase 3 1.77521
BAG6 BCL2-associated athanogene 6 1.74839
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.72511
MCCD1 mitochondrial coiled-coil domain 1 1.68304
C5ORF56 chromosome 5 open reading frame 56 1.67753
HLA-F-AS1 HLA-F antisense RNA 1 1.65338
EHMT2 euchromatic histone-lysine N-methyltransferase 2 1.61275
CLEC16A C-type lectin domain family 16, member A 1.60953
HLA-DMB major histocompatibility complex, class II, DM beta 1.59758
C2 complement component 2 1.59036
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 1.58785
CD58 CD58 molecule 1.57669
NKX2-3 NK2 homeobox 3 1.57618
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.56471
CTSH cathepsin H 1.53391
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.53181
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 1.5289
IL13 interleukin 13 1.52471
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 1.52471
EVI5 ecotropic viral integration site 5 1.52131
TAGAP T-cell activation RhoGTPase activating protein 1.51826
ZGPAT zinc finger, CCCH-type with G patch domain 1.51284
CFB complement factor B 1.50254
TRAF1 TNF receptor-associated factor 1 1.47109
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.47109
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 1.45312
AHI1 Abelson helper integration site 1 1.45071
TNPO3 transportin 3 1.43606
LACC1 laccase (multicopper oxidoreductase) domain containing 1 1.4354
BTNL2 butyrophilin-like 2 1.43254
PUS10 pseudouridylate synthase 10 1.42406
TNIP1 TNFAIP3 interacting protein 1 1.42343
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.41938
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.41322
GSDMB gasdermin B 1.41195
FGFR1OP FGFR1 oncogene partner 1.3901
MST1 macrophage stimulating 1 1.38696
MMEL1 membrane metallo-endopeptidase-like 1 1.3772
GLIS3 GLIS family zinc finger 3 1.37205
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.34523
ANKRD55 ankyrin repeat domain 55 1.32323
CD86 CD86 molecule 1.3216
SIRPG signal-regulatory protein gamma 1.31441
IL2RA interleukin 2 receptor, alpha 1.3084
HLA-DMA major histocompatibility complex, class II, DM alpha 1.30678
CCR6 chemokine (C-C motif) receptor 6 1.30573
CD69 CD69 molecule 1.29672
IFIH1 interferon induced with helicase C domain 1 1.29479
PRKD2 protein kinase D2 1.28315
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 1.27905
METTL1 methyltransferase like 1 1.25806
CDSN corneodesmosin 1.25749
PSORS1C1 psoriasis susceptibility 1 candidate 1 1.24306
POU5F1 POU class 5 homeobox 1 1.24285
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.24074
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.21015
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase 1.21015
SP140 SP140 nuclear body protein 1.21015
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.20157
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.20045
TCF19 transcription factor 19 1.19923
KIF1B kinesin family member 1B 1.19535
SLC30A7 solute carrier family 30 (zinc transporter), member 7 1.19535
BANK1 B-cell scaffold protein with ankyrin repeats 1 1.18824
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 1.18223
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 1.17966
BRD2 bromodomain containing 2 1.17931
NCOA5 nuclear receptor coactivator 5 1.17897
SPRED2 sprouty-related, EVH1 domain containing 2 1.17732
PPT2 palmitoyl-protein thioesterase 2 1.16482
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.16279
ZMIZ1 zinc finger, MIZ-type containing 1 1.16237
STAT2 signal transducer and activator of transcription 2, 113kDa 1.1596
LOC100506459 uncharacterized LOC100506459 1.1553
ITLN1 intelectin 1 (galactofuranose binding) 1.14861
JAZF1 JAZF zinc finger 1 1.14783
C1ORF106 chromosome 1 open reading frame 106 1.14001
ATXN2L ataxin 2-like 1.14001
HORMAD2 HORMA domain containing 2 1.14001
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 1.14001
SBNO2 strawberry notch homolog 2 (Drosophila) 1.13837
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 1.13508
ICOSLG inducible T-cell co-stimulator ligand 1.13415
AGER advanced glycosylation end product-specific receptor 1.13195
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 1.12829
CD247 CD247 molecule 1.12829
MALT1 MALT1 paracaspase 1.12829
CD6 CD6 molecule 1.11923
IGF2 insulin-like growth factor 2 1.11923
PHRF1 PHD and ring finger domains 1 1.11262
ZNF767P zinc finger family member 767, pseudogene 1.11197
MAPK1 mitogen-activated protein kinase 1 1.11197
DKKL1 dickkopf-like 1 1.11197
SKAP2 src kinase associated phosphoprotein 2 1.10994
ICOS inducible T-cell co-stimulator 1.10686
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 1.10562
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.10404
PXK PX domain containing serine/threonine kinase 1.0996
PLEK pleckstrin 1.09596
PVT1 Pvt1 oncogene (non-protein coding) 1.09492
ARHGAP31 Rho GTPase activating protein 31 1.09478
CD40 CD40 molecule, TNF receptor superfamily member 5 1.09396
CLECL1 C-type lectin-like 1 1.0857
SPATA2 spermatogenesis associated 2 1.0857
MPV17L2 MPV17 mitochondrial membrane protein-like 2 1.0857
MERTK MER proto-oncogene, tyrosine kinase 1.0857
CD226 CD226 molecule 1.0857
C6ORF15 chromosome 6 open reading frame 15 1.05713
ADAD1 adenosine deaminase domain containing 1 (testis-specific) 1.05478
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 1.0512
BATF basic leucine zipper transcription factor, ATF-like 1.0512
ODF3B outer dense fiber of sperm tails 3B 1.0512
IL7R interleukin 7 receptor 1.0512
UBASH3A ubiquitin associated and SH3 domain containing A 1.0512
CTNNA3 catenin (cadherin-associated protein), alpha 3 1.04216
MLANA melan-A 1.03074
ZFP90 ZFP90 zinc finger protein 1.03074
LOC100506047 uncharacterized LOC100506047 1.03074
SLC44A4 solute carrier family 44, member 4 1.02811
IL17REL interleukin 17 receptor E-like 1.01732
C5ORF30 chromosome 5 open reading frame 30 1.01619
FAM107A family with sequence similarity 107, member A 1.01035
HLA-F major histocompatibility complex, class I, F 0.983871
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.971629
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.967381
SOX5 SRY (sex determining region Y)-box 5 0.964823
ZBTB46 zinc finger and BTB domain containing 46 0.964823
MANBA mannosidase, beta A, lysosomal 0.964823
PRRC2A proline-rich coiled-coil 2A 0.959251
HSPA1L heat shock 70kDa protein 1-like 0.929905
STK19 serine/threonine kinase 19 0.918051
LEKR1 leucine, glutamate and lysine rich 1 0.917611
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.910428
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.910428
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) 0.891716
HCG22 HLA complex group 22 0.880437
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.87535
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.87535
GRB10 growth factor receptor-bound protein 10 0.871217
SPEF2 sperm flagellar 2 0.850808
LOC100294145 uncharacterized LOC100294145 0.848339
NELFE negative elongation factor complex member E 0.834958
SAE1 SUMO1 activating enzyme subunit 1 0.832503
AK5 adenylate kinase 5 0.821415
SUMF1 sulfatase modifying factor 1 0.818094
MSH5 mutS homolog 5 0.811121
PDZRN4 PDZ domain containing ring finger 4 0.806918
MYNN myoneurin 0.805784
MPHOSPH9 M-phase phosphoprotein 9 0.805784
C1ORF204 chromosome 1 open reading frame 204 0.805784
TMEM39A transmembrane protein 39A 0.805784
CLSTN2 calsyntenin 2 0.795254
SYK spleen tyrosine kinase 0.785549
PVR poliovirus receptor 0.776599
ZNF433 zinc finger protein 433 0.776599
VAV2 vav 2 guanine nucleotide exchange factor 0.776599
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 0.776599
KIF21B kinesin family member 21B 0.776599
GPC5 glypican 5 0.776599
TRIM31 tripartite motif containing 31 0.75296
KANK1 KN motif and ankyrin repeat domains 1 0.728415
DPCR1 diffuse panbronchiolitis critical region 1 0.720934
CSMD1 CUB and Sushi multiple domains 1 0.713648
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.713648
LINC01551 long intergenic non-protein coding RNA 1551 0.713648
NDFIP1 Nedd4 family interacting protein 1 0.713648
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.710472
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 0.675926
FCRL3 Fc receptor-like 3 0.673444
RPL5 ribosomal protein L5 0.673444
RREB1 ras responsive element binding protein 1 0.673444
RELN reelin 0.673444
NRXN1 neurexin 1 0.668358
FHIT fragile histidine triad 0.663201
MOG myelin oligodendrocyte glycoprotein 0.658737
PCDH7 protocadherin 7 0.647255
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.643715
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 0.643715
EGFL6 EGF-like-domain, multiple 6 0.643715
ALPK2 alpha-kinase 2 0.643715
NLRP11 NLR family, pyrin domain containing 11 0.643715
TRIM2 tripartite motif containing 2 0.643715
PLCL2 phospholipase C-like 2 0.643715
LRRC16A leucine rich repeat containing 16A 0.642359
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.636631
TIAM1 T-cell lymphoma invasion and metastasis 1 0.628467
FAM179A family with sequence similarity 179, member A 0.620185
PCSK5 proprotein convertase subtilisin/kexin type 5 0.619978
TLL1 tolloid-like 1 0.619978
DNM3 dynamin 3 0.618667
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.600919
MET MET proto-oncogene, receptor tyrosine kinase 0.600919
AXDND1 axonemal dynein light chain domain containing 1 0.600919
OPCML opioid binding protein/cell adhesion molecule-like 0.597723
TG thyroglobulin 0.597559
GGT1 gamma-glutamyltransferase 1 0.594881
RBMS3 RNA binding motif, single stranded interacting protein 3 0.593024
KPNB1 karyopherin (importin) beta 1 0.586342
IL12A interleukin 12A 0.585423
LOC100506023 uncharacterized LOC100506023 0.585423
NCKAP5 NCK-associated protein 5 0.585423
GPR75-ASB3 GPR75-ASB3 readthrough 0.584073
SAMD12 sterile alpha motif domain containing 12 0.573989
POPDC3 popeye domain containing 3 0.573989
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.573989
POU2F3 POU class 2 homeobox 3 0.573253
TGFBR3 transforming growth factor, beta receptor III 0.568185
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.561623
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.559586
HSDL1 hydroxysteroid dehydrogenase like 1 0.559586
ETV6 ets variant 6 0.55768
CDH18 cadherin 18, type 2 0.554352
DYSF dysferlin 0.552055
FAM69A family with sequence similarity 69, member A 0.551496
ELMO1 engulfment and cell motility 1 0.550943
ERBB4 erb-b2 receptor tyrosine kinase 4 0.547224
PHACTR2 phosphatase and actin regulator 2 0.546207
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.54521
TRIM10 tripartite motif containing 10 0.544232
NRG1 neuregulin 1 0.544193
HDAC9 histone deacetylase 9 0.54375
SDCBP2 syndecan binding protein (syntenin) 2 0.541945
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 0.541403
NXN nucleoredoxin 0.540835
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.537256
TBC1D4 TBC1 domain family, member 4 0.536331
CLDN14 claudin 14 0.535678
RNF213 ring finger protein 213 0.534402
PARD3B par-3 family cell polarity regulator beta 0.532557
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.53137
SMAD3 SMAD family member 3 0.529931
EFNA5 ephrin-A5 0.528815
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 0.52696
MCTP2 multiple C2 domains, transmembrane 2 0.526199
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.525948
GRM7 glutamate receptor, metabotropic 7 0.522821
DGKQ diacylglycerol kinase, theta 110kDa 0.521455
DPPA2 developmental pluripotency associated 2 0.521232
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.52057
HEMK1 HemK methyltransferase family member 1 0.520352
MAML3 mastermind-like 3 (Drosophila) 0.518231
CCHCR1 coiled-coil alpha-helical rod protein 1 0.518231
NKAIN2 Na+/K+ transporting ATPase interacting 2 0.517211
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 0.517211
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.517211
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.515825
EVA1A eva-1 homolog A (C. elegans) 0.514281
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.513694
CD300A CD300a molecule 0.513501
CNTN6 contactin 6 0.512063
ZNF423 zinc finger protein 423 0.511427
WNT16 wingless-type MMTV integration site family, member 16 0.510289
NSD1 nuclear receptor binding SET domain protein 1 0.51016
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.509982
COL27A1 collagen, type XXVII, alpha 1 0.509452
OSBP2 oxysterol binding protein 2 0.508665
RSPO2 R-spondin 2 0.506111
SLIT3 slit homolog 3 (Drosophila) 0.50513
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.504816
DENND1A DENN/MADD domain containing 1A 0.503129
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.502979
LRRC4C leucine rich repeat containing 4C 0.502385
PSORS1C2 psoriasis susceptibility 1 candidate 2 0.501944
ANKRD26P3 ankyrin repeat domain 26 pseudogene 3 0.501799
GRIK1 glutamate receptor, ionotropic, kainate 1 0.501221
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.500025
CTNND2 catenin (cadherin-associated protein), delta 2 0.499578
STX8 syntaxin 8 0.49943
E2F5 E2F transcription factor 5, p130-binding 0.498843
MAGEB10 melanoma antigen family B10 0.498408
TNP2 transition protein 2 (during histone to protamine replacement) 0.496988
TRAPPC9 trafficking protein particle complex 9 0.494545
LOC388210 0.494414
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.493891
CPVL carboxypeptidase, vitellogenic-like 0.493503
MUC22 mucin 22 0.492738
PTCHD1-AS PTCHD1 antisense RNA (head to head) 0.491862
CPE carboxypeptidase E 0.490762
KSR2 kinase suppressor of ras 2 0.486259
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.486021
CADM2 cell adhesion molecule 2 0.485197
MUC21 mucin 21, cell surface associated 0.484965
SYN3 synapsin III 0.484389
ZBTB20 zinc finger and BTB domain containing 20 0.482813
KIAA1211 KIAA1211 0.482702
CPNE4 copine IV 0.482154
AACS acetoacetyl-CoA synthetase 0.479817
RIN2 Ras and Rab interactor 2 0.477891
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 0.477398
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.476428
TRIM26 tripartite motif containing 26 0.476332
ASB3 ankyrin repeat and SOCS box containing 3 0.475855
APOM apolipoprotein M 0.473998
DYX1C1 dyslexia susceptibility 1 candidate 1 0.473636
A2ML1 alpha-2-macroglobulin-like 1 0.472129
PLXNA2 plexin A2 0.470121
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.468231
IL6 interleukin 6 0.466497
NCF4 neutrophil cytosolic factor 4, 40kDa 0.466497
EPHA6 EPH receptor A6 0.466412
SFSWAP splicing factor, suppressor of white-apricot family 0.466327
LOC158435 uncharacterized LOC158435 0.466158
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.465737
ARHGAP17 Rho GTPase activating protein 17 0.465404
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 0.464825
ZFP69 ZFP69 zinc finger protein 0.463688
IL7 interleukin 7 0.461878
RAB3B RAB3B, member RAS oncogene family 0.46157
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like 0.45969
RRP1B ribosomal RNA processing 1B 0.458958
ALK anaplastic lymphoma receptor tyrosine kinase 0.458166
ARMC9 armadillo repeat containing 9 0.456073
GFI1 growth factor independent 1 transcription repressor 0.455733
KDM4C lysine (K)-specific demethylase 4C 0.455461
AGBL1 ATP/GTP binding protein-like 1 0.455461
TSPAN16 tetraspanin 16 0.455253
IRAK2 interleukin-1 receptor-associated kinase 2 0.454773
GRIK4 glutamate receptor, ionotropic, kainate 4 0.45423
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough 0.453759
DSCAML1 Down syndrome cell adhesion molecule like 1 0.453693
NOL10 nucleolar protein 10 0.453493
TENM4 teneurin transmembrane protein 4 0.45303
CENPM centromere protein M 0.452964
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 0.452898
CHODL chondrolectin 0.452052
NPAS3 neuronal PAS domain protein 3 0.451603
C1QB complement component 1, q subcomponent, B chain 0.448752
WLS wntless Wnt ligand secretion mediator 0.44778
SUSD3 sushi domain containing 3 0.447097
DOCK2 dedicator of cytokinesis 2 0.446865
SORBS2 sorbin and SH3 domain containing 2 0.446405
CADPS2 Ca++-dependent secretion activator 2 0.445893
FBXO32 F-box protein 32 0.445779
USP8 ubiquitin specific peptidase 8 0.445386
HPGDS hematopoietic prostaglandin D synthase 0.444829
LRRK1 leucine-rich repeat kinase 1 0.443789
UNC5B unc-5 homolog B (C. elegans) 0.442508
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.442037
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.436613
ICAM3 intercellular adhesion molecule 3 0.433532
PDZD2 PDZ domain containing 2 0.424316
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.423926
TTYH2 tweety family member 2 0.42134
IL12RB2 interleukin 12 receptor, beta 2 0.416856
HAPLN1 hyaluronan and proteoglycan link protein 1 0.416601
COL25A1 collagen, type XXV, alpha 1 0.416601
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 0.412467
FAM19A1 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 0.410555
MXD1 MAX dimerization protein 1 0.404612
HDGFRP3 hepatoma-derived growth factor, related protein 3 0.404282
DIAPH1 diaphanous-related formin 1 0.403737
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.403153
LOC440600 uncharacterized LOC440600 0.402144
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.400844
CCDC170 coiled-coil domain containing 170 0.399759
DSCAM Down syndrome cell adhesion molecule 0.399169
STK39 serine threonine kinase 39 0.397329
LUC7L LUC7-like (S. cerevisiae) 0.395395
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12 0.38917
NRXN2 neurexin 2 0.388032
CCND3 cyclin D3 0.377409
FAM3C family with sequence similarity 3, member C 0.372259
LRP5 low density lipoprotein receptor-related protein 5 0.36675
CPED1 cadherin-like and PC-esterase domain containing 1 0.361923
TMPRSS6 transmembrane protease, serine 6 0.3607
C17ORF53 chromosome 17 open reading frame 53 0.357107
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 0.355305
FUBP3 far upstream element (FUSE) binding protein 3 0.347104
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.341776
G6PD glucose-6-phosphate dehydrogenase 0.340886
SP7 Sp7 transcription factor 0.336113
JAG1 jagged 1 0.329972
SH2B3 SH2B adaptor protein 3 0.328726
SMG6 SMG6 nonsense mediated mRNA decay factor 0.326715
AXIN1 axin 1 0.311525
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 0.308824
MARK3 MAP/microtubule affinity-regulating kinase 3 0.30528
HFE hemochromatosis 0.304098
HOXC4 homeobox C4 0.303474
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.299362
IDUA iduronidase, alpha-L- 0.29505
LIPC lipase, hepatic 0.291815
RCL1 RNA terminal phosphate cyclase-like 1 0.287577
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 0.286805
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.28617
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.280125
ALPL alkaline phosphatase, liver/bone/kidney 0.271497
NME8 NME/NM23 family member 8 0.27053
PNPLA3 patatin-like phospholipase domain containing 3 0.263585
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.263526
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 0.259703
IP6K3 inositol hexakisphosphate kinase 3 0.254081
GCKR glucokinase (hexokinase 4) regulator 0.253475
DCDC5 doublecortin domain containing 5 0.250075
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 0.250075
THPO thrombopoietin 0.244369
MAPT microtubule-associated protein tau 0.244369
ESR1 estrogen receptor 1 0.243234
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.242411
GPATCH1 G patch domain containing 1 0.242277
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.237178
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 0.235812
SLC14A2 solute carrier family 14 (urea transporter), member 2 0.235812
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 0.233341
THRB thyroid hormone receptor, beta 0.23237
KIAA2018 KIAA2018 0.231596
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 0.229142
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.227851
CPN1 carboxypeptidase N, polypeptide 1 0.22638
TMEM263 transmembrane protein 263 0.225666
DOCK7 dedicator of cytokinesis 7 0.221129
FMN2 formin 2 0.220993
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.220993
HBA1 hemoglobin, alpha 1 0.218672
DENND4A DENN/MADD domain containing 4A 0.218555
TMEM79 transmembrane protein 79 0.218283
C12ORF4 chromosome 12 open reading frame 4 0.216371
CSTA cystatin A (stefin A) 0.216371
BRAP BRCA1 associated protein 0.214893
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.212674
SAMM50 SAMM50 sorting and assembly machinery component 0.212544
MEF2C myocyte enhancer factor 2C 0.211024
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.210334
CRHR1 corticotropin releasing hormone receptor 1 0.210334
STK24 serine/threonine kinase 24 0.20719
WDR72 WD repeat domain 72 0.206644
SPTBN1 spectrin, beta, non-erythrocytic 1 0.205552
FTCDNL1 formiminotransferase cyclodeaminase N-terminal like 0.205552
HDAC5 histone deacetylase 5 0.205552
CDK6 cyclin-dependent kinase 6 0.205552
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 0.205552
COL4A2 collagen, type IV, alpha 2 0.203809
TERT telomerase reverse transcriptase 0.202391
XPO7 exportin 7 0.202391
RPS11 ribosomal protein S11 0.202391
LRP2 low density lipoprotein receptor-related protein 2 0.200681
PRKCE protein kinase C, epsilon 0.200537
MECOM MDS1 and EVI1 complex locus 0.200161
RAP1A RAP1A, member of RAS oncogene family 0.200161
TYMP thymidine phosphorylase 0.200161
CCDC162P coiled-coil domain containing 162, pseudogene 0.198722
NRCAM neuronal cell adhesion molecule 0.198439
FAM210A family with sequence similarity 210, member A 0.198439
RGS14 regulator of G-protein signaling 14 0.196725
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.193135
AKAP6 A kinase (PRKA) anchor protein 6 0.190583
TFR2 transferrin receptor 2 0.189575
CETP cholesteryl ester transfer protein, plasma 0.189297
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 0.187895
XKR9 XK, Kell blood group complex subunit-related family, member 9 0.187895
BAZ1B bromodomain adjacent to zinc finger domain, 1B 0.184858
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 0.183521
OSBPL1A oxysterol binding protein-like 1A 0.182717
SOX6 SRY (sex determining region Y)-box 6 0.182717
MMP26 matrix metallopeptidase 26 0.181043
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.180666
CKAP5 cytoskeleton associated protein 5 0.177694
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.176493
IBSP integrin-binding sialoprotein 0.176447
GALP galanin-like peptide 0.176103
LOC100133286 uncharacterized LOC100133286 0.175349
DOK6 docking protein 6 0.175349
TNR tenascin R 0.174539
LOC100507377 uncharacterized LOC100507377 0.17437
CTNNBL1 catenin, beta like 1 0.17437
NCAPH2 non-SMC condensin II complex, subunit H2 0.17437
MMP25 matrix metallopeptidase 25 0.171941
EPO erythropoietin 0.171941
MCM8 minichromosome maintenance complex component 8 0.171258
IL21R interleukin 21 receptor 0.167983
PTK7 protein tyrosine kinase 7 (inactive) 0.167537
LRP4 low density lipoprotein receptor-related protein 4 0.167537
RERE arginine-glutamic acid dipeptide (RE) repeats 0.16429
CNTNAP2 contactin associated protein-like 2 0.16429
ETFB electron-transfer-flavoprotein, beta polypeptide 0.163453
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.162894
KIAA1644 KIAA1644 0.162791
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 0.16244
WDFY4 WDFY family member 4 0.16127
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.160748
GPALPP1 GPALPP motifs containing 1 0.160256
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 0.158925
RYR3 ryanodine receptor 3 0.15671
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.156545
TBC1D22A TBC1 domain family, member 22A 0.156261
NSRP1 nuclear speckle splicing regulatory protein 1 0.155373
COL11A1 collagen, type XI, alpha 1 0.154438
ITFG3 integrin alpha FG-GAP repeat containing 3 0.15432
ZNF789 zinc finger protein 789 0.153504
RORA RAR-related orphan receptor A 0.152743
TIAM2 T-cell lymphoma invasion and metastasis 2 0.151749
LINC00303 long intergenic non-protein coding RNA 303 0.150882
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.149099
SDK1 sidekick cell adhesion molecule 1 0.148096
ZNF667 zinc finger protein 667 0.14796
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17 0.14796
LYN LYN proto-oncogene, Src family tyrosine kinase 0.14796
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.147893
SARNP SAP domain containing ribonucleoprotein 0.147893
PDE7B phosphodiesterase 7B 0.147303
OSMR oncostatin M receptor 0.146926
MVB12A multivesicular body subunit 12A 0.146562
CCDC146 coiled-coil domain containing 146 0.146267
SLC38A7 solute carrier family 38, member 7 0.146151
ADAM19 ADAM metallopeptidase domain 19 0.146094
SP100 SP100 nuclear antigen 0.145923
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.145003
FRMD4A FERM domain containing 4A 0.145003
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.144797
SOAT1 sterol O-acyltransferase 1 0.144495
ESRRG estrogen-related receptor gamma 0.144201
IPO8 importin 8 0.143962
AFF3 AF4/FMR2 family, member 3 0.143914
SLC26A5 solute carrier family 26 (anion exchanger), member 5 0.143635
CATSPERB catsper channel auxiliary subunit beta 0.142668
AUH AU RNA binding protein/enoyl-CoA hydratase 0.142668
FOXK1 forkhead box K1 0.142254
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.141895
CAMKMT calmodulin-lysine N-methyltransferase 0.140954
SLC39A11 solute carrier family 39, member 11 0.139727
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.139727
MSH2 mutS homolog 2 0.138979
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.138652
APOC1 apolipoprotein C-I 0.13825
STK32B serine/threonine kinase 32B 0.138221
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.137673
FLJ46010 0.137646
IFT80 intraflagellar transport 80 0.13641
RPGRIP1L RPGRIP1-like 0.13641
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.135496
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.135474
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 0.135279
ATP10B ATPase, class V, type 10B 0.135279
EEF1DP3 eukaryotic translation elongation factor 1 delta pseudogene 3 0.135108
FREM1 FRAS1 related extracellular matrix 1 0.134693
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.134293
FMNL2 formin-like 2 0.134079
BTBD10 BTB (POZ) domain containing 10 0.133907
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.133571
KCNK12 potassium channel, two pore domain subfamily K, member 12 0.133498
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.133227
GOLGB1 golgin B1 0.132454
ARID5B AT rich interactive domain 5B (MRF1-like) 0.132355
ATP10A ATPase, class V, type 10A 0.132323
OTOGL otogelin-like 0.13229
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 0.131656
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 0.131503
FLT1 fms-related tyrosine kinase 1 0.13113
CLVS1 clavesin 1 0.130912
NMT1 N-myristoyltransferase 1 0.130912
CCM2 cerebral cavernous malformation 2 0.130883
DTWD2 DTW domain containing 2 0.130203
DCAKD dephospho-CoA kinase domain containing 0.12982
FAM13A family with sequence similarity 13, member A 0.129807
FAM155A family with sequence similarity 155, member A 0.129691
EXOC4 exocyst complex component 4 0.129588
FYB FYN binding protein 0.129424
SPATA2L spermatogenesis associated 2-like 0.12935
LIN28B lin-28 homolog B (C. elegans) 0.129312
TM7SF2 transmembrane 7 superfamily member 2 0.129067
ECI2 enoyl-CoA delta isomerase 2 0.128971
CPN2 carboxypeptidase N, polypeptide 2 0.128947
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 0.12884
TRRAP transformation/transcription domain-associated protein 0.128524
C8ORF34 chromosome 8 open reading frame 34 0.128398
TPM4 tropomyosin 4 0.128364
WIPF1 WAS/WASL interacting protein family, member 1 0.128051
ZAN zonadhesin (gene/pseudogene) 0.127184
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 0.126983
PCAT4 prostate cancer associated transcript 4 (non-protein coding) 0.126983
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.124346
PDE4D phosphodiesterase 4D, cAMP-specific 0.112665
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.11065
MYB v-myb avian myeloblastosis viral oncogene homolog 0.110567
SLC17A3 solute carrier family 17 (organic anion transporter), member 3 0.109661
LRP1B low density lipoprotein receptor-related protein 1B 0.107625
TFRC transferrin receptor 0.106578
SPTA1 spectrin, alpha, erythrocytic 1 0.105372
CNTN4 contactin 4 0.101907
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.101184