abnormal behavioral response to addictive substance Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the behavioral response induced by an addictive substance, such as induced hyperactivity or stereotypic behavior (Mammalian Phenotype Ontology, MP_0009748)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009748
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Genes

75 gene mutations causing the abnormal behavioral response to addictive substance phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADGRL3 adhesion G protein-coupled receptor L3
ADORA2A adenosine A2a receptor
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
AQP4 aquaporin 4
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CALCB calcitonin-related polypeptide beta
CCKBR cholecystokinin B receptor
CD81 CD81 molecule
CHRM5 cholinergic receptor, muscarinic 5
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
CREB1 cAMP responsive element binding protein 1
CRHR1 corticotropin releasing hormone receptor 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DLG4 discs, large homolog 4 (Drosophila)
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
FYN FYN proto-oncogene, Src family tyrosine kinase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRASP GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRK6 G protein-coupled receptor kinase 6
GRM5 glutamate receptor, metabotropic 5
HIPK2 homeodomain interacting protein kinase 2
HOMER1 homer scaffolding protein 1
HOMER2 homer scaffolding protein 2
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IL6 interleukin 6
LMO4 LIM domain only 4
LRRK2 leucine-rich repeat kinase 2
NACC1 nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
NOS1 nitric oxide synthase 1 (neuronal)
NPY1R neuropeptide Y receptor Y1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
PDLIM5 PDZ and LIM domain 5
PENK proenkephalin
PER2 period circadian clock 2
PLAT plasminogen activator, tissue
POMC proopiomelanocortin
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCG protein kinase C, gamma
PRLHR prolactin releasing hormone receptor
RGS4 regulator of G-protein signaling 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
TAAR1 trace amine associated receptor 1
TACR1 tachykinin receptor 1
TAOK2 TAO kinase 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UNC79 unc-79 homolog (C. elegans)
WFS1 Wolfram syndrome 1 (wolframin)