abnormal azygos vein morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the unpaired vein which in humans arises from the right ascending lumbar vein or the vena cava, enters the thorax through the aortic orifice in the diaphragm, and terminates in the superior vena cava; unlike humans, mice have a single and left-sided azygos vein that develops from the paired embryonic cardinal venous system and drains most of the right and left thoracic walls into the left anterior vena cava (Mammalian Phenotype Ontology, MP_0011569)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011569
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Genes

4 gene mutations causing the abnormal azygos vein morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CFC1 cripto, FRL-1, cryptic family 1
DRC1 dynein regulatory complex subunit 1
LEFTY1 left-right determination factor 1
PITX2 paired-like homeodomain 2