abdominal aortic aneurysm Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An aortic aneurysm that is located_in the abdominal aorta. (Human Disease Ontology, DOID_7693)
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Genes

191 genes co-occuring with the disease abdominal aortic aneurysm in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
AAAS achalasia, adrenocortical insufficiency, alacrimia 3.78832
MMP9 matrix metallopeptidase 9 1.80201
MMP2 matrix metallopeptidase 2 1.65295
APOE apolipoprotein E 1.43464
TIMP1 TIMP metallopeptidase inhibitor 1 1.24037
C17ORF85 chromosome 17 open reading frame 85 1.15837
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.1072
CRP C-reactive protein, pentraxin-related 1.04756
MMP12 matrix metallopeptidase 12 1.02945
CCL2 chemokine (C-C motif) ligand 2 1.02735
MMP1 matrix metallopeptidase 1 1.02566
PGRMC1 progesterone receptor membrane component 1 1.01976
CTSS cathepsin S 0.992752
CMA1 chymase 1, mast cell 0.957868
C1ORF105 chromosome 1 open reading frame 105 0.95745
IL6 interleukin 6 0.918848
TIMP2 TIMP metallopeptidase inhibitor 2 0.903621
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.900335
CR1L complement component (3b/4b) receptor 1-like 0.874919
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.865502
MMP3 matrix metallopeptidase 3 0.821667
ACE angiotensin I converting enzyme 0.806898
MFAP4 microfibrillar-associated protein 4 0.782707
CST3 cystatin C 0.782298
SPP1 secreted phosphoprotein 1 0.772479
ELN elastin 0.749237
LDLR low density lipoprotein receptor 0.744766
DAB2IP DAB2 interacting protein 0.741111
PLG plasminogen 0.735838
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.716425
TIMP3 TIMP metallopeptidase inhibitor 3 0.703938
MMP8 matrix metallopeptidase 8 0.701526
ALB albumin 0.693098
PLAU plasminogen activator, urokinase 0.689492
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 0.687491
PHF12 PHD finger protein 12 0.686291
CD68 CD68 molecule 0.663181
F2 coagulation factor II (thrombin) 0.657234
PLAT plasminogen activator, tissue 0.656046
ARL4C ADP-ribosylation factor-like 4C 0.651298
ELANE elastase, neutrophil expressed 0.645375
MMP13 matrix metallopeptidase 13 0.643009
IL1B interleukin 1, beta 0.630813
F3 coagulation factor III (thromboplastin, tissue factor) 0.62728
LTBP4 latent transforming growth factor beta binding protein 4 0.620226
TNXB tenascin XB 0.613183
MFAP2 microfibrillar-associated protein 2 0.608494
TNXA tenascin XA (pseudogene) 0.605372
FBXL20 F-box and leucine-rich repeat protein 20 0.597571
HBA2 hemoglobin, alpha 2 0.56722
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.565277
HP haptoglobin 0.564112
HPR haptoglobin-related protein 0.557897
EXOC3 exocyst complex component 3 0.557509
HBA1 hemoglobin, alpha 1 0.55518
PTGES prostaglandin E synthase 0.550911
FBN1 fibrillin 1 0.549747
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.548195
C8G complement component 8, gamma polypeptide 0.529222
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.521502
C8A complement component 8, alpha polypeptide 0.521502
TNNI3 troponin I type 3 (cardiac) 0.519961
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.516879
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 0.515725
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 0.503058
CPB2 carboxypeptidase B2 (plasma) 0.499614
ENOSF1 enolase superfamily member 1 0.496557
CTSG cathepsin G 0.489691
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 0.48893
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.488549
JUN jun proto-oncogene 0.479047
ALYREF Aly/REF export factor 0.477151
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.468063
RRBP1 ribosome binding protein 1 0.461639
IL9R interleukin 9 receptor 0.456355
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.453716
C8B complement component 8, beta polypeptide 0.452962
TNF tumor necrosis factor 0.447687
VCAM1 vascular cell adhesion molecule 1 0.445052
HAS1 hyaluronan synthase 1 0.4443
LOX lysyl oxidase 0.439786
BGN biglycan 0.432646
PRUNE2 prune homolog 2 (Drosophila) 0.427015
TGFB1 transforming growth factor, beta 1 0.42664
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.42364
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.420641
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.416896
ALOX5 arachidonate 5-lipoxygenase 0.415398
DDO D-aspartate oxidase 0.407919
ADAM17 ADAM metallopeptidase domain 17 0.406051
TNNT2 troponin T type 2 (cardiac) 0.400453
BHMT2 betaine--homocysteine S-methyltransferase 2 0.398589
ATG4B autophagy related 4B, cysteine peptidase 0.397098
LCN2 lipocalin 2 0.387051
DNM3 dynamin 3 0.385936
TGFBR1 transforming growth factor, beta receptor 1 0.382594
COL3A1 collagen, type III, alpha 1 0.379256
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.377031
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.375179
CTSD cathepsin D 0.373328
BHMT betaine--homocysteine S-methyltransferase 0.372958
MARCKSL1 MARCKS-like 1 0.372217
ZFYVE1 zinc finger, FYVE domain containing 1 0.372217
NOS3 nitric oxide synthase 3 (endothelial cell) 0.369258
CLPS colipase, pancreatic 0.36741
AURKC aurora kinase C 0.36187
BAD BCL2-associated agonist of cell death 0.358551
ICAM1 intercellular adhesion molecule 1 0.356709
CXCL8 chemokine (C-X-C motif) ligand 8 0.344574
BCO1 beta-carotene oxygenase 1 0.344207
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.340173
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.339806
THBD thrombomodulin 0.337975
VEGFA vascular endothelial growth factor A 0.337608
SCPEP1 serine carboxypeptidase 1 0.335046
FLNB filamin B, beta 0.32993
CTSB cathepsin B 0.324823
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.321909
KIAA0101 KIAA0101 0.321181
MPO myeloperoxidase 0.320817
SORT1 sortilin 1 0.317909
CCR2 chemokine (C-C motif) receptor 2 0.313189
IL10 interleukin 10 0.312464
CD4 CD4 molecule 0.311739
PRRC2A proline-rich coiled-coil 2A 0.309566
AGTR1 angiotensin II receptor, type 1 0.308842
MAL mal, T-cell differentiation protein 0.307395
VCAN versican 0.307395
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.305226
LTB4R leukotriene B4 receptor 0.298011
CKLF chemokine-like factor 0.297291
MMP24 matrix metallopeptidase 24 (membrane-inserted) 0.294053
C5AR1 complement component 5a receptor 1 0.291898
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.281153
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.275445
GYLTL1B glycosyltransferase-like 1B 0.269398
FRG2B FSHD region gene 2 family, member B 0.267622
AMH anti-Mullerian hormone 0.266558
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.261245
DUOX1 dual oxidase 1 0.251015
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 0.248554
TIMP4 TIMP metallopeptidase inhibitor 4 0.241546
PDE9A phosphodiesterase 9A 0.238752
MAPK8 mitogen-activated protein kinase 8 0.238054
FKBP2 FK506 binding protein 2, 13kDa 0.234225
DUOX2 dual oxidase 2 0.232142
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 0.231448
IGF1 insulin-like growth factor 1 (somatomedin C) 0.225229
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.224884
TNC tenascin C 0.223853
CD40LG CD40 ligand 0.220424
CTSA cathepsin A 0.218034
FAM131C family with sequence similarity 131, member C 0.217012
CNTN3 contactin 3 (plasmacytoma associated) 0.215653
XYLT1 xylosyltransferase I 0.215314
ANGPTL2 angiopoietin-like 2 0.214636
VWF von Willebrand factor 0.212945
HMGB1 high mobility group box 1 0.209583
CD79A CD79a molecule, immunoglobulin-associated alpha 0.208579
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.20658
SELE selectin E 0.20658
SCNN1D sodium channel, non voltage gated 1 delta subunit 0.204263
ERAS ES cell expressed Ras 0.200982
TBPL1 TBP-like 1 0.200331
ADCY7 adenylate cyclase 7 0.200331
LGALS3 lectin, galactoside-binding, soluble, 3 0.197099
MMP23B matrix metallopeptidase 23B 0.194865
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.191719
CD69 CD69 molecule 0.191408
HMOX1 heme oxygenase 1 0.190168
UCN2 urocortin 2 0.188326
MMP25 matrix metallopeptidase 25 0.187719
CDC27 cell division cycle 27 0.187113
DCN decorin 0.18621
MBL2 mannose-binding lectin (protein C) 2, soluble 0.182957
CDON cell adhesion associated, oncogene regulated 0.182666
TAS1R1 taste receptor, type 1, member 1 0.180084
FGD1 FYVE, RhoGEF and PH domain containing 1 0.177576
PLA2G10 phospholipase A2, group X 0.176215
MMP28 matrix metallopeptidase 28 0.173314
KERA keratocan 0.16933
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.16933
CCL3 chemokine (C-C motif) ligand 3 0.168381
PRKCD protein kinase C, delta 0.168381
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.167224
CXCR2 chemokine (C-X-C motif) receptor 2 0.166095
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.164786
TPI1 triosephosphate isomerase 1 0.164149
CREM cAMP responsive element modulator 0.161912
CAT catalase 0.159302
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.157602