WM-266-4 Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Homo sapiens (human) skin melanoma cell line. The WM-266-4 cell line was derived from a metastatic site of a malignant melanoma from a 58 year old female organism. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001595)
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Genes

137 genes mutated in the WM-266-4 cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ADAM9 ADAM metallopeptidase domain 9
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARHGAP11A Rho GTPase activating protein 11A
ARSJ arylsulfatase family, member J
ASCC3 activating signal cointegrator 1 complex subunit 3
ATF5 activating transcription factor 5
AURKB aurora kinase B
BBS7 Bardet-Biedl syndrome 7
BCL9 B-cell CLL/lymphoma 9
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD1 bromodomain containing 1
C15ORF52 chromosome 15 open reading frame 52
C1QTNF2 C1q and tumor necrosis factor related protein 2
C4ORF33 chromosome 4 open reading frame 33
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNTROB centrobin, centrosomal BRCA2 interacting protein
CPT1B carnitine palmitoyltransferase 1B (muscle)
CREB3 cAMP responsive element binding protein 3
CWC22 CWC22 spliceosome-associated protein
DAAM2 dishevelled associated activator of morphogenesis 2
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DPF1 D4, zinc and double PHD fingers family 1
DST dystonin
DTNB dystrobrevin, beta
EBF1 early B-cell factor 1
EFCAB2 EF-hand calcium binding domain 2
ERGIC3 ERGIC and golgi 3
FAAH fatty acid amide hydrolase
FAM178B family with sequence similarity 178, member B
FAM208B family with sequence similarity 208, member B
FAM222A family with sequence similarity 222, member A
FBLN2 fibulin 2
FBN1 fibrillin 1
FBRSL1 fibrosin-like 1
GEMIN5 gem (nuclear organelle) associated protein 5
GPS2 G protein pathway suppressor 2
GTF2H5 general transcription factor IIH, polypeptide 5
HDAC7 histone deacetylase 7
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HPN hepsin
ICE2 interactor of little elongation complex ELL subunit 2
IDE insulin-degrading enzyme
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
ILF3 interleukin enhancer binding factor 3, 90kDa
IQCK IQ motif containing K
ITGA7 integrin, alpha 7
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0355 KIAA0355
KIF4B kinesin family member 4B
KLHL29 kelch-like family member 29
KPNA3 karyopherin alpha 3 (importin alpha 4)
LMF2 lipase maturation factor 2
LOC81691 exonuclease NEF-sp
LPIN1 lipin 1
LRP12 low density lipoprotein receptor-related protein 12
MCCC1 methylcrotonoyl-CoA carboxylase 1 (alpha)
MDN1 MDN1, midasin homolog (yeast)
MET MET proto-oncogene, receptor tyrosine kinase
MKI67 marker of proliferation Ki-67
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MON1B MON1 secretory trafficking family member B
MPDZ multiple PDZ domain protein
MTMR11 myotubularin related protein 11
MYH10 myosin, heavy chain 10, non-muscle
MYO18A myosin XVIIIA
MYO9B myosin IXB
NCOR1 nuclear receptor corepressor 1
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
NLRP1 NLR family, pyrin domain containing 1
OSBPL5 oxysterol binding protein-like 5
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PAQR7 progestin and adipoQ receptor family member VII
PBX3 pre-B-cell leukemia homeobox 3
PCDHB13 protocadherin beta 13
PFAS phosphoribosylformylglycinamidine synthase
PHKB phosphorylase kinase, beta
PKN1 protein kinase N1
PLEC plectin
PLEKHN1 pleckstrin homology domain containing, family N member 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PML promyelocytic leukemia
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
QSER1 glutamine and serine rich 1
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RABIF RAB interacting factor
RARG retinoic acid receptor, gamma
RBAK RB-associated KRAB zinc finger
RBM20 RNA binding motif protein 20
RHOT2 ras homolog family member T2
RPTOR regulatory associated protein of MTOR, complex 1
RXRA retinoid X receptor, alpha
S1PR5 sphingosine-1-phosphate receptor 5
SAMHD1 SAM domain and HD domain 1
SATB2 SATB homeobox 2
SCAF1 SR-related CTD-associated factor 1
SDSL serine dehydratase-like
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGK223 homolog of rat pragma of Rnd2
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10
SMAD4 SMAD family member 4
SMC3 structural maintenance of chromosomes 3
SNRPA small nuclear ribonucleoprotein polypeptide A
SSRP1 structure specific recognition protein 1
ST7L suppression of tumorigenicity 7 like
STARD13 StAR-related lipid transfer (START) domain containing 13
TACC1 transforming, acidic coiled-coil containing protein 1
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCF20 transcription factor 20 (AR1)
TCTN2 tectonic family member 2
TFAP2E transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
TGS1 trimethylguanosine synthase 1
TICRR TOPBP1-interacting checkpoint and replication regulator
TLE2 transducin-like enhancer of split 2
TOPBP1 topoisomerase (DNA) II binding protein 1
TRIP6 thyroid hormone receptor interactor 6
TSKU tsukushi, small leucine rich proteoglycan
UHRF1BP1 UHRF1 binding protein 1
URI1 URI1, prefoldin-like chaperone
USP42 ubiquitin specific peptidase 42
WDR3 WD repeat domain 3
WDR62 WD repeat domain 62
ZCCHC2 zinc finger, CCHC domain containing 2
ZNF148 zinc finger protein 148
ZNF251 zinc finger protein 251
ZNF280D zinc finger protein 280D
ZNF511 zinc finger protein 511
ZNF628 zinc finger protein 628
ZRANB1 zinc finger, RAN-binding domain containing 1