Triglycerides Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description disease cluster belonging to disease group metabolic (Genetic Association Database)
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Genes

244 genes associated with the trait Triglycerides in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
ZPR1 ZPR1 zinc finger 2.79439
GCKR glucokinase (hexokinase 4) regulator 2.45779
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 2.44814
TBL2 transducin (beta)-like 2 1.98035
APOB apolipoprotein B 1.86879
DOCK7 dedicator of cytokinesis 7 1.83553
SUGP1 SURP and G patch domain containing 1 1.67144
DSCAML1 Down syndrome cell adhesion molecule like 1 1.6692
LPL lipoprotein lipase 1.64848
APOA5 apolipoprotein A-V 1.57498
FADS1 fatty acid desaturase 1 1.52815
TDRKH tudor and KH domain containing 1.45018
BUD13 BUD13 homolog (S. cerevisiae) 1.30017
ADGRL2 adhesion G protein-coupled receptor L2 1.23935
BAZ1B bromodomain adjacent to zinc finger domain, 1B 1.20587
GRM7 glutamate receptor, metabotropic 7 1.18609
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 1.18594
EDN3 endothelin 3 1.15172
CHD7 chromodomain helicase DNA binding protein 7 1.13617
JMJD1C jumonji domain containing 1C 1.04648
TIMD4 T-cell immunoglobulin and mucin domain containing 4 1.03943
AFF1 AF4/FMR2 family, member 1 1.01773
FRMD5 FERM domain containing 5 0.995026
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.975942
PCIF1 PDX1 C-terminal inhibiting factor 1 0.955241
MLXIPL MLX interacting protein-like 0.944178
BLZF1 basic leucine zipper nuclear factor 1 0.937068
LOC100287651 0.929739
TAGLN transgelin 0.922056
PCSK7 proprotein convertase subtilisin/kexin type 7 0.922056
EPHA4 EPH receptor A4 0.908617
KRTAP1-3 keratin associated protein 1-3 0.890075
PLCL2 phospholipase C-like 2 0.880024
TYW1B tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) 0.862644
SUSD4 sushi domain containing 4 0.859711
CASC15 cancer susceptibility candidate 15 (non-protein coding) 0.835298
FBXL7 F-box and leucine-rich repeat protein 7 0.819386
SPON1 spondin 1, extracellular matrix protein 0.785833
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.777975
BACE2 beta-site APP-cleaving enzyme 2 0.771485
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.763999
ZNF664 zinc finger protein 664 0.763999
CAPN3 calpain 3, (p94) 0.731179
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.711358
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.702833
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.696869
ZNF101 zinc finger protein 101 0.696869
SIK3 SIK family kinase 3 0.685324
GHRL ghrelin/obestatin prepropeptide 0.682865
CCDC102B coiled-coil domain containing 102B 0.676279
CD180 CD180 molecule 0.663085
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 0.64828
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 0.634604
ITPK1 inositol-tetrakisphosphate 1-kinase 0.63306
METAP1 methionyl aminopeptidase 1 0.632044
PDE4D phosphodiesterase 4D, cAMP-specific 0.620718
ZMIZ1 zinc finger, MIZ-type containing 1 0.579445
RB1 retinoblastoma 1 0.574246
FAM117B family with sequence similarity 117, member B 0.571117
PCNT pericentrin 0.554216
CAMKMT calmodulin-lysine N-methyltransferase 0.551027
CCSER1 coiled-coil serine-rich protein 1 0.548157
TSHZ2 teashirt zinc finger homeobox 2 0.546355
JAKMIP1 janus kinase and microtubule interacting protein 1 0.535173
LPIN2 lipin 2 0.52906
NTM neurotrimin 0.52739
GLIS3 GLIS family zinc finger 3 0.512619
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.508617
KMT2C lysine (K)-specific methyltransferase 2C 0.492441
ATP13A5 ATPase type 13A5 0.490247
TEK TEK tyrosine kinase, endothelial 0.478929
NUP37 nucleoporin 37kDa 0.473329
CPNE4 copine IV 0.471267
PRSS38 protease, serine, 38 0.459481
FLRT2 fibronectin leucine rich transmembrane protein 2 0.452586
DCHS2 dachsous cadherin-related 2 0.451307
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.445556
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.443956
SOX5 SRY (sex determining region Y)-box 5 0.443956
IKZF2 IKAROS family zinc finger 2 (Helios) 0.441757
ESRRG estrogen-related receptor gamma 0.440411
EHF ets homologous factor 0.439992
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.439903
ARHGAP15 Rho GTPase activating protein 15 0.432689
C16ORF62 chromosome 16 open reading frame 62 0.429556
SYT9 synaptotagmin IX 0.428113
FAM19A1 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 0.417683
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.416793
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.412046
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 0.410891
CLNK cytokine-dependent hematopoietic cell linker 0.409784
FADS2 fatty acid desaturase 2 0.406869
CCSER2 coiled-coil serine-rich protein 2 0.406015
TTC13 tetratricopeptide repeat domain 13 0.402838
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.390008
DPP4 dipeptidyl-peptidase 4 0.389591
RABGAP1L RAB GTPase activating protein 1-like 0.386175
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.381512
NID2 nidogen 2 (osteonidogen) 0.380257
ADGRB3 adhesion G protein-coupled receptor B3 0.378873
FRMPD4 FERM and PDZ domain containing 4 0.361153
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.358915
APOC1 apolipoprotein C-I 0.356676
LMBRD1 LMBR1 domain containing 1 0.354266
GRID1 glutamate receptor, ionotropic, delta 1 0.352169
PRRX1 paired related homeobox 1 0.350806
STK31 serine/threonine kinase 31 0.345582
SYNE1 spectrin repeat containing, nuclear envelope 1 0.344017
SLC12A8 solute carrier family 12, member 8 0.342805
NRXN1 neurexin 1 0.340325
COBLL1 cordon-bleu WH2 repeat protein-like 1 0.33862
CNTNAP5 contactin associated protein-like 5 0.33862
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 0.33862
SFPQ splicing factor proline/glutamine-rich 0.337387
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.327469
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.326373
DTWD2 DTW domain containing 2 0.324821
ZCCHC16 zinc finger, CCHC domain containing 16 0.323533
SCFD1 sec1 family domain containing 1 0.320397
TTN titin 0.31998
ASTN1 astrotactin 1 0.319757
FRZB frizzled-related protein 0.319092
SSBP3 single stranded DNA binding protein 3 0.315377
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 0.312075
ARHGAP26 Rho GTPase activating protein 26 0.309063
PEBP4 phosphatidylethanolamine-binding protein 4 0.300387
F13A1 coagulation factor XIII, A1 polypeptide 0.299646
FAM135B family with sequence similarity 135, member B 0.298789
COL1A1 collagen, type I, alpha 1 0.297569
PPP1R2P3 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 3 0.295765
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.294508
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.287814
PCDH9 protocadherin 9 0.284999
PDE10A phosphodiesterase 10A 0.276749
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.275939
SCGN secretagogin, EF-hand calcium binding protein 0.275282
CPLX2 complexin 2 0.265725
KLHL13 kelch-like family member 13 0.265634
MASTL microtubule associated serine/threonine kinase-like 0.264819
DOCK4 dedicator of cytokinesis 4 0.259807
GPM6A glycoprotein M6A 0.259476
COL27A1 collagen, type XXVII, alpha 1 0.258486
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 0.256094
PTPRD protein tyrosine phosphatase, receptor type, D 0.256093
FRMPD1 FERM and PDZ domain containing 1 0.255378
NBPF3 neuroblastoma breakpoint family, member 3 0.254421
KEL Kell blood group, metallo-endopeptidase 0.248995
UBA5 ubiquitin-like modifier activating enzyme 5 0.24456
HCG27 HLA complex group 27 (non-protein coding) 0.244175
RGS7 regulator of G-protein signaling 7 0.240811
CDH7 cadherin 7, type 2 0.238602
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.238555
MICB MHC class I polypeptide-related sequence B 0.236695
PRG4 proteoglycan 4 0.236638
GCK glucokinase (hexokinase 4) 0.23502
TMOD1 tropomodulin 1 0.232889
SCN3B sodium channel, voltage gated, type III beta subunit 0.232134
NXPH1 neurexophilin 1 0.229312
CCP110 centriolar coiled coil protein 110kDa 0.228816
ACOXL acyl-CoA oxidase-like 0.215167
NRG1 neuregulin 1 0.214089
CERS3 ceramide synthase 3 0.21258
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.212418
LPP LIM domain containing preferred translocation partner in lipoma 0.207679
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.206205
LTBP1 latent transforming growth factor beta binding protein 1 0.203407
PTN pleiotrophin 0.200538
TRDN triadin 0.200459
CCDC141 coiled-coil domain containing 141 0.19955
FBLN5 fibulin 5 0.199236
MARCO macrophage receptor with collagenous structure 0.194441
AIRE autoimmune regulator 0.193192
PFKL phosphofructokinase, liver 0.193192
AVEN apoptosis, caspase activation inhibitor 0.185928
VIT vitrin 0.175174
LAMA1 laminin, alpha 1 0.173902
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.172547
PALM2 paralemmin 2 0.170319
GRIK2 glutamate receptor, ionotropic, kainate 2 0.168885
POMC proopiomelanocortin 0.164129
PACRG PARK2 co-regulated 0.163152
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.15617
CSMD1 CUB and Sushi multiple domains 1 0.148917
NCAM2 neural cell adhesion molecule 2 0.146282
SV2C synaptic vesicle glycoprotein 2C 0.145826
EPS8 epidermal growth factor receptor pathway substrate 8 0.144687
RPL7P16 ribosomal protein L7 pseudogene 16 0.141518
LGI2 leucine-rich repeat LGI family, member 2 0.141397
IGFBP4 insulin-like growth factor binding protein 4 0.135988
SOBP sine oculis binding protein homolog (Drosophila) 0.135279
RTN4 reticulon 4 0.135128
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 0.133714
GRM8 glutamate receptor, metabotropic 8 0.132686
CAPSL calcyphosine-like 0.126578
HMBOX1 homeobox containing 1 0.125067
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.123562
KCNK13 potassium channel, two pore domain subfamily K, member 13 0.123033
MUSK muscle, skeletal, receptor tyrosine kinase 0.121529
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.118672
PARVA parvin, alpha 0.116929
BRD2 bromodomain containing 2 0.116421
ST13P8 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 8 0.116421
NOTCH4 notch 4 0.115816
SPNS2 spinster homolog 2 (Drosophila) 0.113786
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.11339
C2ORF16 chromosome 2 open reading frame 16 0.113085
DPYD dihydropyrimidine dehydrogenase 0.112888
MLIP muscular LMNA-interacting protein 0.112593
POU6F2 POU class 6 homeobox 2 0.111861
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38 0.109886
PFKP phosphofructokinase, platelet 0.107099
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 0.103419
QRFPR pyroglutamylated RFamide peptide receptor 0.102978
PLXDC2 plexin domain containing 2 0.101335
KCNIP4 Kv channel interacting protein 4 0.094965
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.093363
ZC3H7A zinc finger CCCH-type containing 7A 0.092482
SLC26A5 solute carrier family 26 (anion exchanger), member 5 0.09175
TTC9 tetratricopeptide repeat domain 9 0.088445
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.085512
PRPF31 pre-mRNA processing factor 31 0.085197
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.08465
ZRANB3 zinc finger, RAN-binding domain containing 3 0.082554
R3HDM1 R3H domain containing 1 0.082554
IQGAP2 IQ motif containing GTPase activating protein 2 0.080798
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 0.077968
FYN FYN proto-oncogene, Src family tyrosine kinase 0.074052
CADPS2 Ca++-dependent secretion activator 2 0.073142
WBSCR17 Williams-Beuren syndrome chromosome region 17 0.069901
TMC5 transmembrane channel-like 5 0.069374
PCDH15 protocadherin-related 15 0.068768
PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 0.068632
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.068358
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.068318
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 0.066648
KIAA1217 KIAA1217 0.065956
HDAC4 histone deacetylase 4 0.063681
SGCZ sarcoglycan, zeta 0.06169
CENPI centromere protein I 0.06038
ACBD6 acyl-CoA binding domain containing 6 0.060053
IFITM10 interferon induced transmembrane protein 10 0.059437
EPHA3 EPH receptor A3 0.058978
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.058858
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 0.05875