Tic Disorders Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D013981
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Genes

122 genes/proteins associated with the disease Tic Disorders from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
DRD4 dopamine receptor D4 2.88009
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.88009
DRD2 dopamine receptor D2 2.19026
PRL prolactin 1.92642
DRD1 dopamine receptor D1 1.87261
TH tyrosine hydroxylase 1.85852
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.83396
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.77686
BDNF brain-derived neurotrophic factor 1.72322
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.70906
FOS FBJ murine osteosarcoma viral oncogene homolog 1.70823
MAOB monoamine oxidase B 1.69659
NUPR1 nuclear protein, transcriptional regulator, 1 1.65731
CDK5 cyclin-dependent kinase 5 1.65709
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.63563
DRD3 dopamine receptor D3 1.6296
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.59567
GRIK2 glutamate receptor, ionotropic, kainate 2 1.59427
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.57402
ARC activity-regulated cytoskeleton-associated protein 1.55108
NPY neuropeptide Y 1.5479
EGR1 early growth response 1 1.53772
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.52693
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.48659
GSK3B glycogen synthase kinase 3 beta 1.48659
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.47787
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.4583
HOMER1 homer scaffolding protein 1 1.45803
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.44355
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.44219
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.41559
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.41146
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.3827
CREB1 cAMP responsive element binding protein 1 1.38071
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.36418
INHA inhibin, alpha 1.35647
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.35357
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.3388
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.32399
C10ORF10 chromosome 10 open reading frame 10 1.32192
PENK proenkephalin 1.30451
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.30329
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.30269
RELN reelin 1.29996
BCL2 B-cell CLL/lymphoma 2 1.29875
CRH corticotropin releasing hormone 1.2861
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.28395
TNF tumor necrosis factor 1.27966
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.2744
MAOA monoamine oxidase A 1.27009
FNDC4 fibronectin type III domain containing 4 1.26825
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 1.26794
JUN jun proto-oncogene 1.25307
MAPK1 mitogen-activated protein kinase 1 1.24905
CAT catalase 1.24623
POMC proopiomelanocortin 1.24496
GDNF glial cell derived neurotrophic factor 1.23993
INHBE inhibin, beta E 1.2352
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.20654
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.2046
ADORA2A adenosine A2a receptor 1.2046
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.18489
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.18424
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.18293
TAGLN transgelin 1.18126
JUND jun D proto-oncogene 1.16302
GRM1 glutamate receptor, metabotropic 1 1.16001
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.15661
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.15256
MAPK3 mitogen-activated protein kinase 3 1.14885
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.14781
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.14404
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.1437
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.13758
FABP1 fatty acid binding protein 1, liver 1.13621
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.13518
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.13279
CCND1 cyclin D1 1.12771
CCND3 cyclin D3 1.12668
BAX BCL2-associated X protein 1.12288
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 1.1198
OPRM1 opioid receptor, mu 1 1.11911
MAPK8 mitogen-activated protein kinase 8 1.11809
EYA2 EYA transcriptional coactivator and phosphatase 2 1.1129
INS insulin 1.10942
SYT4 synaptotagmin IV 1.10734
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.10424
EFNB3 ephrin-B3 1.09541
RAB12 RAB12, member RAS oncogene family 1.09506
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 1.09401
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.0919
RGS4 regulator of G-protein signaling 4 1.09154
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.0894
SOD1 superoxide dismutase 1, soluble 1.08762
GAL galanin/GMAP prepropeptide 1.08407
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.08231
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.08126
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.07947
GFAP glial fibrillary acidic protein 1.07447
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.07269
GRIK5 glutamate receptor, ionotropic, kainate 5 1.06844
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.06808
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.0637
FAM45A family with sequence similarity 45, member A 1.0608
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.059
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.05461
NPTX2 neuronal pentraxin II 1.05386
GRK6 G protein-coupled receptor kinase 6 1.05015
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.03976
HES5 hes family bHLH transcription factor 5 1.03939
JUNB jun B proto-oncogene 1.03901
PLP1 proteolipid protein 1 1.03084
PDE4A phosphodiesterase 4A, cAMP-specific 1.02708
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 1.02634
IL6 interleukin 6 1.02336
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.02003
CRY1 cryptochrome circadian clock 1 1.01814
STX4 syntaxin 4 1.01625
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 1.01474
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.01399
DUSP1 dual specificity phosphatase 1 1.01212
ADCY5 adenylate cyclase 5 1.01099