Tachycardia, Sinus Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D013616
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Genes

170 genes/proteins associated with the disease Tachycardia, Sinus from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
GCG glucagon 2.88009
MAPK3 mitogen-activated protein kinase 3 2.18037
TNF tumor necrosis factor 2.17217
FOS FBJ murine osteosarcoma viral oncogene homolog 2.16319
MAPK1 mitogen-activated protein kinase 1 2.13645
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.09904
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.07914
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 2.06611
CAT catalase 2.01691
BDNF brain-derived neurotrophic factor 2.01146
IL6 interleukin 6 2.00481
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.99827
BAX BCL2-associated X protein 1.95721
BCL2 B-cell CLL/lymphoma 2 1.90705
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.85852
EDN1 endothelin 1 1.84587
SOD1 superoxide dismutase 1, soluble 1.83307
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.82551
NPPA natriuretic peptide A 1.80397
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.77394
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.754
DRD1 dopamine receptor D1 1.73858
MAPK8 mitogen-activated protein kinase 8 1.72509
CREB1 cAMP responsive element binding protein 1 1.72137
NOS2 nitric oxide synthase 2, inducible 1.71912
REN renin 1.68062
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.6774
ADRB1 adrenoceptor beta 1 1.67376
VEGFA vascular endothelial growth factor A 1.6636
JUN jun proto-oncogene 1.66296
CRH corticotropin releasing hormone 1.66038
MAPK14 mitogen-activated protein kinase 14 1.65292
IL1B interleukin 1, beta 1.63765
EGR1 early growth response 1 1.62893
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.62713
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.62246
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.60641
GSTP1 glutathione S-transferase pi 1 1.60082
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.57735
ADRB2 adrenoceptor beta 2, surface 1.57641
CCND3 cyclin D3 1.55157
INS insulin 1.5433
FAS Fas cell surface death receptor 1.53917
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.53917
POMC proopiomelanocortin 1.53772
IL10 interleukin 10 1.51708
ODC1 ornithine decarboxylase 1 1.51456
CCL2 chemokine (C-C motif) ligand 2 1.50725
GNAS GNAS complex locus 1.50574
TAC1 tachykinin, precursor 1 1.50273
S100A9 S100 calcium binding protein A9 1.49019
DRD2 dopamine receptor D2 1.4727
CDK5 cyclin-dependent kinase 5 1.47089
TGFB1 transforming growth factor, beta 1 1.45484
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.45405
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.43537
MAOA monoamine oxidase A 1.42777
CXCL8 chemokine (C-X-C motif) ligand 8 1.41911
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.41285
ADRBK1 adrenergic, beta, receptor kinase 1 1.41035
EGFR epidermal growth factor receptor 1.3998
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.38669
HMOX1 heme oxygenase 1 1.35676
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.35415
NTS neurotensin 1.34869
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.34576
BCL2L1 BCL2-like 1 1.34401
ADRB3 adrenoceptor beta 3 1.33995
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.32993
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.32816
IGF1 insulin-like growth factor 1 (somatomedin C) 1.32518
CCND1 cyclin D1 1.32369
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.32074
GJA1 gap junction protein, alpha 1, 43kDa 1.32015
SOD2 superoxide dismutase 2, mitochondrial 1.31807
TGFB2 transforming growth factor, beta 2 1.31267
F3 coagulation factor III (thromboplastin, tissue factor) 1.29781
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.29256
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.28889
CREM cAMP responsive element modulator 1.28889
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.27193
THRA thyroid hormone receptor, alpha 1.27162
TP53 tumor protein p53 1.27101
MAPK9 mitogen-activated protein kinase 9 1.26917
CCL3 chemokine (C-C motif) ligand 3 1.26669
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.26638
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.26545
PRL prolactin 1.26421
TAGLN transgelin 1.26021
NOS1 nitric oxide synthase 1 (neuronal) 1.24905
CES2 carboxylesterase 2 1.23837
COMT catechol-O-methyltransferase 1.23806
CALCA calcitonin-related polypeptide alpha 1.23042
S100A8 S100 calcium binding protein A8 1.22145
GSK3B glycogen synthase kinase 3 beta 1.21076
PRKCZ protein kinase C, zeta 1.20848
G6PD glucose-6-phosphate dehydrogenase 1.20687
NPPB natriuretic peptide B 1.20558
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.19445
NPY neuropeptide Y 1.18652
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.18059
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.18026
PPARG peroxisome proliferator-activated receptor gamma 1.17827
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.17235
VCAM1 vascular cell adhesion molecule 1 1.16368
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.15797
RYR2 ryanodine receptor 2 (cardiac) 1.15022
BTG3 BTG family, member 3 1.14234
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.1403
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.13963
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.13758
CDK2 cyclin-dependent kinase 2 1.13518
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.13484
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.13313
IL2 interleukin 2 1.12495
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.12048
PARP1 poly (ADP-ribose) polymerase 1 1.11945
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.11396
MPO myeloperoxidase 1.1122
AVP arginine vasopressin 1.11116
TNNI3 troponin I type 3 (cardiac) 1.11011
EGR2 early growth response 2 1.10907
LDLR low density lipoprotein receptor 1.10838
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.10699
FNDC4 fibronectin type III domain containing 4 1.10493
MED13L mediator complex subunit 13-like 1.10459
SREBF2 sterol regulatory element binding transcription factor 2 1.10353
EDNRA endothelin receptor type A 1.10246
MAP2K1 mitogen-activated protein kinase kinase 1 1.09506
IFNG interferon, gamma 1.09083
MMP9 matrix metallopeptidase 9 1.0894
JUNB jun B proto-oncogene 1.08655
PRKCE protein kinase C, epsilon 1.08619
IL4 interleukin 4 1.08478
MMP2 matrix metallopeptidase 2 1.08478
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.08442
PRKCB protein kinase C, beta 1.08407
MAOB monoamine oxidase B 1.08407
PKM pyruvate kinase, muscle 1.08407
PENK proenkephalin 1.08407
TIMP1 TIMP metallopeptidase inhibitor 1 1.08372
IL18 interleukin 18 1.08231
RHOA ras homolog family member A 1.07804
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.07696
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 1.07128
FGF2 fibroblast growth factor 2 (basic) 1.07128
GSR glutathione reductase 1.06987
RGS4 regulator of G-protein signaling 4 1.06917
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.06297
DRD5 dopamine receptor D5 1.0608
GAL galanin/GMAP prepropeptide 1.06044
ARC activity-regulated cytoskeleton-associated protein 1.05461
BDKRB2 bradykinin receptor B2 1.052
SYN2 synapsin II 1.05052
COL1A1 collagen, type I, alpha 1 1.04904
ADRA2A adrenoceptor alpha 2A 1.04647
PLCG1 phospholipase C, gamma 1 1.04611
TH tyrosine hydroxylase 1.04465
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.04088
SGK1 serum/glucocorticoid regulated kinase 1 1.03715
NUPR1 nuclear protein, transcriptional regulator, 1 1.03715
ADCY5 adenylate cyclase 5 1.03641
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 1.03159
ACTA2 actin, alpha 2, smooth muscle, aorta 1.03084
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 1.02746
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.01966
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.01249
UNG uracil-DNA glycosylase 1.01212
IL1A interleukin 1, alpha 1.01212
ICAM1 intercellular adhesion molecule 1 1.01137