TNF-alpha NF-kB Signaling Pathway(Mus musculus) Gene Set

Dataset Wikipathways Pathways
Category structural or functional annotations
Type pathway
External Link http://www.wikipathways.org/instance/WP246_r69201
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Genes

179 proteins participating in the TNF-alpha NF-kB Signaling Pathway(Mus musculus) pathway from the Wikipathways Pathways dataset.

Symbol Name
ACTL6A actin-like 6A
AKAP8 A kinase (PRKA) anchor protein 8
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALPL alkaline phosphatase, liver/bone/kidney
AZI2 5-azacytidine induced 2
BAG4 BCL2-associated athanogene 4
BCL3 B-cell CLL/lymphoma 3
BCL7A B-cell CLL/lymphoma 7A
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAPN3 calpain 3, (p94)
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CAV1 caveolin 1, caveolae protein, 22kDa
CCAR2 cell cycle and apoptosis regulator 2
CD3EAP CD3e molecule, epsilon associated protein
CDC34 cell division cycle 34
CDC37 cell division cycle 37
CFLAR CASP8 and FADD-like apoptosis regulator
CHUK conserved helix-loop-helix ubiquitous kinase
COMMD1 copper metabolism (Murr1) domain containing 1
COPS3 COP9 signalosome subunit 3
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CREBBP CREB binding protein
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2B casein kinase 2, beta polypeptide
CUL1 cullin 1
CYLD cylindromatosis (turban tumor syndrome)
DAP death-associated protein
DCAF7 DDB1 and CUL4 associated factor 7
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DPF2 D4, zinc and double PHD fingers family 2
EIF4A3 eukaryotic translation initiation factor 4A3
FADD Fas (TNFRSF6)-associated via death domain
FAF1 Fas (TNFRSF6) associated factor 1
FANCD2 Fanconi anemia, complementation group D2
FBL fibrillarin
FBXW11 F-box and WD repeat domain containing 11
FKBP5 FK506 binding protein 5
FLNA filamin A, alpha
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GAB1 GRB2-associated binding protein 1
GLG1 golgi glycoprotein 1
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GSK3B glycogen synthase kinase 3 beta
GTF2I general transcription factor IIi
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC6 histone deacetylase 6
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPB1 heat shock 27kDa protein 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IQGAP2 IQ motif containing GTPase activating protein 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KPNA3 karyopherin alpha 3 (importin alpha 4)
KPNA6 karyopherin alpha 6 (importin alpha 7)
LRPPRC leucine-rich pentatricopeptide repeat containing
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MARK2 MAP/microtubule affinity-regulating kinase 2
MCC mutated in colorectal cancers
MCM5 minichromosome maintenance complex component 5
MCM7 minichromosome maintenance complex component 7
MTIF2 mitochondrial translational initiation factor 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NKIRAS1 NFKB inhibitor interacting Ras-like 1
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NLRP4 NLR family, pyrin domain containing 4
NR2C2 nuclear receptor subfamily 2, group C, member 2
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
PAPOLA poly(A) polymerase alpha
PDCD2 programmed cell death 2
PEBP1 phosphatidylethanolamine binding protein 1
PEG3 paternally expressed 3
PFDN2 prefoldin subunit 2
PIAS3 protein inhibitor of activated STAT, 3
PKN1 protein kinase N1
PML promyelocytic leukemia
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POLR1C polymerase (RNA) I polypeptide C, 30kDa
POLR1D polymerase (RNA) I polypeptide D, 16kDa
POLR1E polymerase (RNA) I polypeptide E, 53kDa
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCZ protein kinase C, zeta
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
PTK2 protein tyrosine kinase 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RASAL2 RAS protein activator like 2
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK2 receptor-interacting serine-threonine kinase 2
RIPK3 receptor-interacting serine-threonine kinase 3
RNF216 ring finger protein 216
RNF25 ring finger protein 25
RPL30 ribosomal protein L30
RPL4 ribosomal protein L4
RPL6 ribosomal protein L6
RPL8 ribosomal protein L8
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SKP1 S-phase kinase-associated protein 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
SUMO1 small ubiquitin-like modifier 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TIFA TRAF-interacting protein with forkhead-associated domain
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNIP1 TNFAIP3 interacting protein 1
TNIP2 TNFAIP3 interacting protein 2
TRADD TNFRSF1A-associated via death domain
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAF3 TNF receptor-associated factor 3
TRAF4 TNF receptor-associated factor 4
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TXLNA taxilin alpha
UBE2I ubiquitin-conjugating enzyme E2I
UNC5CL unc-5 homolog C (C. elegans)-like
USP11 ubiquitin specific peptidase 11
USP2 ubiquitin specific peptidase 2
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZFAND5 zinc finger, AN1-type domain 5