TNF alpha Signaling Pathway(Homo sapiens) Gene Set

Dataset Wikipathways Pathways
Category structural or functional annotations
Type pathway
External Link http://www.wikipathways.org/instance/WP231_r81070
Similar Terms
Downloads & Tools

Genes

86 proteins participating in the TNF alpha Signaling Pathway(Homo sapiens) pathway from the Wikipathways Pathways dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
APAF1 apoptotic peptidase activating factor 1
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCL2L1 BCL2-like 1
BID BH3 interacting domain death agonist
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CDC37 cell division cycle 37
CFLAR CASP8 and FADD-like apoptosis regulator
CHUK conserved helix-loop-helix ubiquitous kinase
CREBBP CREB binding protein
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CUL1 cullin 1
CYBA cytochrome b-245, alpha polypeptide
DIABLO diablo, IAP-binding mitochondrial protein
FADD Fas (TNFRSF6)-associated via death domain
FBXW11 F-box and WD repeat domain containing 11
GLUL glutamate-ammonia ligase
GRB2 growth factor receptor-bound protein 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL6 interleukin 6
JUN jun proto-oncogene
KSR1 kinase suppressor of ras 1
KSR2 kinase suppressor of ras 2
LOC100996792 dual specificity mitogen-activated protein kinase kinase 3
MADD MAP-kinase activating death domain
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K6 mitogen-activated protein kinase kinase 6
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NOX1 NADPH oxidase 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
OTUD7B OTU deubiquitinase 7B
PLK1 polo-like kinase 1
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKCZ protein kinase C, zeta
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PYGL phosphorylase, glycogen, liver
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
RFK riboflavin kinase
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
SKP1 S-phase kinase-associated protein 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOS1 son of sevenless homolog 1 (Drosophila)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TRADD TNFRSF1A-associated via death domain
TRAF1 TNF receptor-associated factor 1
TRAF2 TNF receptor-associated factor 2
TRAP1 TNF receptor-associated protein 1
TXN thioredoxin