Spinal Muscular Atrophy, Infantile_CNS - Spinal Cord (MMHCC)_GSE3075 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3075
Similar Terms
Downloads & Tools

Genes

600 genes differentially expressed during Spinal Muscular Atrophy, Infantile_CNS - Spinal Cord (MMHCC)_GSE3075 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
CTDNEP1 CTD nuclear envelope phosphatase 1 4.21757
MTFP1 mitochondrial fission process 1 4.19875
RBMS1 RNA binding motif, single stranded interacting protein 1 3.95665
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 3.8613
C12ORF43 chromosome 12 open reading frame 43 3.63074
USP11 ubiquitin specific peptidase 11 3.53897
SOX2 SRY (sex determining region Y)-box 2 3.52609
TRO trophinin 3.50144
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 3.49193
MRPL22 mitochondrial ribosomal protein L22 3.43055
RIMS2 regulating synaptic membrane exocytosis 2 3.3326
WBP11 WW domain binding protein 11 3.23696
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 3.15236
BRD7 bromodomain containing 7 3.01745
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 2.9648
TBC1D24 TBC1 domain family, member 24 2.92745
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 2.88076
B9D2 B9 protein domain 2 2.86219
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 2.83314
RPS20 ribosomal protein S20 2.82099
HDAC11 histone deacetylase 11 2.79722
NAP1L1 nucleosome assembly protein 1-like 1 2.78778
TMEM132A transmembrane protein 132A 2.75913
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 2.6765
EXOSC7 exosome component 7 2.67524
ZNF330 zinc finger protein 330 2.67341
SRSF9 serine/arginine-rich splicing factor 9 2.63963
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 2.61855
PRPF38B pre-mRNA processing factor 38B 2.5925
TMEM100 transmembrane protein 100 2.58167
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 2.55602
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 2.55592
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 2.49575
NHP2 NHP2 ribonucleoprotein 2.49464
WDR6 WD repeat domain 6 2.48378
UGP2 UDP-glucose pyrophosphorylase 2 2.46422
TPP2 tripeptidyl peptidase II 2.44707
ZNF326 zinc finger protein 326 2.42685
FAM65B family with sequence similarity 65, member B 2.41105
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 2.40767
RND3 Rho family GTPase 3 2.39874
RNF14 ring finger protein 14 2.37789
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 2.36772
DLG3 discs, large homolog 3 (Drosophila) 2.36275
GUCY1B3 guanylate cyclase 1, soluble, beta 3 2.35391
ADGRG1 adhesion G protein-coupled receptor G1 2.3076
SCAMP2 secretory carrier membrane protein 2 2.30365
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.29725
TTC13 tetratricopeptide repeat domain 13 2.24048
NPY neuropeptide Y 2.24038
STMN2 stathmin 2 2.23623
PTPRE protein tyrosine phosphatase, receptor type, E 2.20138
TXNDC9 thioredoxin domain containing 9 2.18925
MRPS6 mitochondrial ribosomal protein S6 2.18559
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 2.18126
RFC3 replication factor C (activator 1) 3, 38kDa 2.16631
PLCL2 phospholipase C-like 2 2.15197
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1 2.11443
PNOC prepronociceptin 2.11333
PHTF2 putative homeodomain transcription factor 2 2.08669
STX1A syntaxin 1A (brain) 2.06394
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 2.06359
RPLP2 ribosomal protein, large, P2 2.03214
KLHL5 kelch-like family member 5 2.01998
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.98437
COPZ1 coatomer protein complex, subunit zeta 1 1.96811
EBF3 early B-cell factor 3 1.96792
UBL3 ubiquitin-like 3 1.95644
DBP D site of albumin promoter (albumin D-box) binding protein 1.95483
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 1.94967
FH fumarate hydratase 1.93915
GSTO1 glutathione S-transferase omega 1 1.93879
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 1.9331
DHRS3 dehydrogenase/reductase (SDR family) member 3 1.93187
SSRP1 structure specific recognition protein 1 1.92843
PHPT1 phosphohistidine phosphatase 1 1.91997
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 1.89454
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 1.89087
SCN2A sodium channel, voltage gated, type II alpha subunit 1.88906
MTMR9 myotubularin related protein 9 1.87203
TMEM199 transmembrane protein 199 1.84984
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 1.847
UBE2K ubiquitin-conjugating enzyme E2K 1.84293
LINGO1 leucine rich repeat and Ig domain containing 1 1.83924
TDG thymine-DNA glycosylase 1.83115
UBE2N ubiquitin-conjugating enzyme E2N 1.82253
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 1.81109
RPS8 ribosomal protein S8 1.79905
EPRS glutamyl-prolyl-tRNA synthetase 1.79825
AGK acylglycerol kinase 1.79609
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 1.7928
CBLN1 cerebellin 1 precursor 1.78194
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 1.78138
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 1.78021
SFXN1 sideroflexin 1 1.77697
TPMT thiopurine S-methyltransferase 1.76514
CAT catalase 1.76273
DZIP1 DAZ interacting zinc finger protein 1 1.76137
ATRAID all-trans retinoic acid-induced differentiation factor 1.75107
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 1.75069
C14ORF79 chromosome 14 open reading frame 79 1.7485
COX18 COX18 cytochrome c oxidase assembly factor 1.74186
ILK integrin-linked kinase 1.7341
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 1.72242
FAM192A family with sequence similarity 192, member A 1.71599
CSAD cysteine sulfinic acid decarboxylase 1.70791
EFNA3 ephrin-A3 1.70332
TIMP4 TIMP metallopeptidase inhibitor 4 1.70306
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 1.69489
TEX11 testis expressed 11 1.6922
TMEM2 transmembrane protein 2 1.65646
EMC2 ER membrane protein complex subunit 2 1.65508
FAM69B family with sequence similarity 69, member B 1.65446
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.64263
GARS glycyl-tRNA synthetase 1.64138
MTX2 metaxin 2 1.63585
ELOVL4 ELOVL fatty acid elongase 4 1.6299
WDR82 WD repeat domain 82 1.62524
EIF3G eukaryotic translation initiation factor 3, subunit G 1.60195
PCBP4 poly(rC) binding protein 4 1.60102
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 1.59964
PRR3 proline rich 3 1.59506
RPS5 ribosomal protein S5 1.5928
RELL1 RELT-like 1 1.58517
NRP1 neuropilin 1 1.58194
TIPRL TOR signaling pathway regulator 1.57838
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) 1.57767
SLC7A4 solute carrier family 7, member 4 1.57412
CBR4 carbonyl reductase 4 1.57288
NBN nibrin 1.56093
POLR2M polymerase (RNA) II (DNA directed) polypeptide M 1.55367
FCGRT Fc fragment of IgG, receptor, transporter, alpha 1.55344
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 1.53709
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.53353
LPCAT1 lysophosphatidylcholine acyltransferase 1 1.52903
SYT9 synaptotagmin IX 1.51466
RARS2 arginyl-tRNA synthetase 2, mitochondrial 1.51218
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 1.51187
C1QTNF4 C1q and tumor necrosis factor related protein 4 1.50376
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 1.49218
FXYD7 FXYD domain containing ion transport regulator 7 1.48082
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 1.47793
STX7 syntaxin 7 1.47715
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 1.46702
KCTD12 potassium channel tetramerization domain containing 12 1.45151
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) 1.45034
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 1.44947
TSN translin 1.44786
EIF3D eukaryotic translation initiation factor 3, subunit D 1.44521
DTYMK deoxythymidylate kinase (thymidylate kinase) 1.43761
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 1.43746
ABHD10 abhydrolase domain containing 10 1.4367
TCEA1 transcription elongation factor A (SII), 1 1.4251
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.41701
NUPL1 nucleoporin like 1 1.41584
LRRTM1 leucine rich repeat transmembrane neuronal 1 1.41233
GYG1 glycogenin 1 1.41142
TAGLN2 transgelin 2 1.41131
TCF12 transcription factor 12 1.39887
LSP1 lymphocyte-specific protein 1 1.39883
LRRC16A leucine rich repeat containing 16A 1.38878
MMD monocyte to macrophage differentiation-associated 1.3882
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 1.38721
TUSC3 tumor suppressor candidate 3 1.37743
SIDT2 SID1 transmembrane family, member 2 1.37538
IGF1 insulin-like growth factor 1 (somatomedin C) 1.37475
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 1.37432
PPAP2B phosphatidic acid phosphatase type 2B 1.37309
RNF38 ring finger protein 38 1.3729
PSIP1 PC4 and SFRS1 interacting protein 1 1.37221
TTC28 tetratricopeptide repeat domain 28 1.36981
TP63 tumor protein p63 1.36475
B3GNT1 1.3597
HAP1 huntingtin-associated protein 1 1.35787
RPL10A ribosomal protein L10a 1.35726
ERGIC3 ERGIC and golgi 3 1.3562
LOC728392 uncharacterized LOC728392 1.35524
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 1.35381
APCDD1 adenomatosis polyposis coli down-regulated 1 1.35307
ARRB2 arrestin, beta 2 1.34556
TRPC3 transient receptor potential cation channel, subfamily C, member 3 1.34198
THEM4 thioesterase superfamily member 4 1.33755
SARNP SAP domain containing ribonucleoprotein 1.33403
MATK megakaryocyte-associated tyrosine kinase 1.33153
WSB2 WD repeat and SOCS box containing 2 1.32126
ERGIC2 ERGIC and golgi 2 1.31453
DERL1 derlin 1 1.31384
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1.30804
RPL6 ribosomal protein L6 1.30658
LDB2 LIM domain binding 2 1.30122
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 1.29805
CHURC1 churchill domain containing 1 1.28233
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa 1.27495
CASP8AP2 caspase 8 associated protein 2 1.27374
RAB12 RAB12, member RAS oncogene family 1.27311
CASD1 CAS1 domain containing 1 1.26952
DDA1 DET1 and DDB1 associated 1 1.26535
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) 1.26445
FABP3 fatty acid binding protein 3, muscle and heart 1.2632
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 1.2556
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 1.25371
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 1.25132
RPP21 ribonuclease P/MRP 21kDa subunit 1.23956
SPRED1 sprouty-related, EVH1 domain containing 1 1.23859
ATAD3A ATPase family, AAA domain containing 3A 1.2374
MCTS1 malignant T cell amplified sequence 1 1.22822
RGS17 regulator of G-protein signaling 17 1.22809
PPP6C protein phosphatase 6, catalytic subunit 1.2229
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 1.22169
ZNF521 zinc finger protein 521 1.22082
MAP2K4 mitogen-activated protein kinase kinase 4 1.22007
CENPT centromere protein T 1.21905
MYL9 myosin, light chain 9, regulatory 1.21214
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 1.20647
AK2 adenylate kinase 2 1.20604
KCTD5 potassium channel tetramerization domain containing 5 1.1992
DOC2A double C2-like domains, alpha 1.19362
SEC13 SEC13 homolog (S. cerevisiae) 1.18966
UNC119 unc-119 homolog (C. elegans) 1.18934
KDM1A lysine (K)-specific demethylase 1A 1.18708
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.18601
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 1.18533
ELP3 elongator acetyltransferase complex subunit 3 1.18509
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) 1.18449
TMED2 transmembrane emp24 domain trafficking protein 2 1.18079
SRSF7 serine/arginine-rich splicing factor 7 1.17837
MCM4 minichromosome maintenance complex component 4 1.17633
MAPRE1 microtubule-associated protein, RP/EB family, member 1 1.17481
SYN2 synapsin II 1.1736
CSE1L CSE1 chromosome segregation 1-like (yeast) 1.1731
PTPRM protein tyrosine phosphatase, receptor type, M 1.17026
USP1 ubiquitin specific peptidase 1 1.16416
CTSV cathepsin V 1.16209
LBX1 ladybird homeobox 1 1.15963
FTL ferritin, light polypeptide 1.15811
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 1.15272
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.15264
RPLP0 ribosomal protein, large, P0 1.15178
SMS spermine synthase 1.15107
SNX2 sorting nexin 2 1.14958
PDZD11 PDZ domain containing 11 1.14896
PRMT1 protein arginine methyltransferase 1 1.14892
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 1.14734
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 1.14347
SYT17 synaptotagmin XVII 1.14199
HMGB2 high mobility group box 2 1.1401
SAFB scaffold attachment factor B 1.13975
CALML4 calmodulin-like 4 1.13957
C9ORF72 chromosome 9 open reading frame 72 1.13455
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 1.13435
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 1.13368
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 1.13334
METTL21A methyltransferase like 21A 1.13249
LARP4B La ribonucleoprotein domain family, member 4B 1.13195
POU6F1 POU class 6 homeobox 1 1.13077
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.1303
TMEM126A transmembrane protein 126A 1.12325
ELAVL1 ELAV like RNA binding protein 1 1.11886
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 1.11869
TTLL1 tubulin tyrosine ligase-like family member 1 1.11749
FSCN1 fascin actin-bundling protein 1 1.1168
NOP56 NOP56 ribonucleoprotein 1.11626
RBM3 RNA binding motif (RNP1, RRM) protein 3 1.11407
MKRN3 makorin ring finger protein 3 1.11405
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 1.11354
NRP2 neuropilin 2 1.11092
BEX1 brain expressed, X-linked 1 1.10993
SEC23A Sec23 homolog A (S. cerevisiae) 1.10835
NFIB nuclear factor I/B 1.10707
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 1.10563
IMPAD1 inositol monophosphatase domain containing 1 1.10529
DEAF1 DEAF1 transcription factor 1.10351
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 1.10331
RNASET2 ribonuclease T2 1.10309
C14ORF166 chromosome 14 open reading frame 166 1.10105
PEX5 peroxisomal biogenesis factor 5 1.09944
HIGD2A HIG1 hypoxia inducible domain family, member 2A 1.0979
BYSL bystin-like 1.09711
STK40 serine/threonine kinase 40 1.09686
CDO1 cysteine dioxygenase type 1 1.09491
CINP cyclin-dependent kinase 2 interacting protein 1.08966
PIH1D1 PIH1 domain containing 1 1.08587
CCL2 chemokine (C-C motif) ligand 2 1.08149
PLCB2 phospholipase C, beta 2 1.08055
TKT transketolase 1.07934
TMEM163 transmembrane protein 163 1.06561
UBE2F ubiquitin-conjugating enzyme E2F (putative) 1.06477
FAM101B family with sequence similarity 101, member B 1.06114
DLAT dihydrolipoamide S-acetyltransferase 1.05897
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.05725
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 1.05511
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 1.05443
EI24 etoposide induced 2.4 1.04955
STX12 syntaxin 12 1.04904
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 1.04733
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.0452
RGS2 regulator of G-protein signaling 2 1.0451
SREBF2 sterol regulatory element binding transcription factor 2 1.04455
GPSM1 G-protein signaling modulator 1 1.04404
MSX1 msh homeobox 1 1.04365

decreased expression

Symbol Name Standardized Value
MIEN1 migration and invasion enhancer 1 -4.65062
PRELP proline/arginine-rich end leucine-rich repeat protein -4.3142
STK19 serine/threonine kinase 19 -4.07915
AUH AU RNA binding protein/enoyl-CoA hydratase -3.94095
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) -3.90886
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -3.73396
GATAD2A GATA zinc finger domain containing 2A -3.42583
PACS2 phosphofurin acidic cluster sorting protein 2 -3.39022
GABARAP GABA(A) receptor-associated protein -3.25015
CDC37L1 cell division cycle 37-like 1 -3.23805
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 -3.17612
SMC6 structural maintenance of chromosomes 6 -3.15102
ISCA1 iron-sulfur cluster assembly 1 -3.03361
TXLNG taxilin gamma -2.99524
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -2.9629
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -2.95867
UBE2L3 ubiquitin-conjugating enzyme E2L 3 -2.84078
TAGLN3 transgelin 3 -2.82369
PIAS1 protein inhibitor of activated STAT, 1 -2.78769
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.76245
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone -2.74007
TPPP3 tubulin polymerization-promoting protein family member 3 -2.69669
TMA7 translation machinery associated 7 homolog (S. cerevisiae) -2.64634
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 -2.60273
CCDC12 coiled-coil domain containing 12 -2.58273
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -2.53517
FNDC4 fibronectin type III domain containing 4 -2.52029
CHODL chondrolectin -2.50229
PRPF31 pre-mRNA processing factor 31 -2.47084
VAMP3 vesicle-associated membrane protein 3 -2.46772
DPP8 dipeptidyl-peptidase 8 -2.46688
DESI1 desumoylating isopeptidase 1 -2.432
FAM127A family with sequence similarity 127, member A -2.40442
LTBP2 latent transforming growth factor beta binding protein 2 -2.39956
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -2.37779
KRTCAP3 keratinocyte associated protein 3 -2.35001
MAG myelin associated glycoprotein -2.3485
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 -2.34171
GPR155 G protein-coupled receptor 155 -2.33089
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.32146
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) -2.30606
SEBOX SEBOX homeobox -2.29013
GTPBP2 GTP binding protein 2 -2.28962
FKBP2 FK506 binding protein 2, 13kDa -2.23429
APOD apolipoprotein D -2.21648
EFCAB7 EF-hand calcium binding domain 7 -2.21094
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 -2.19961
PLA2G16 phospholipase A2, group XVI -2.18331
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted -2.16077
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -2.10507
RBPMS2 RNA binding protein with multiple splicing 2 -2.08389
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.07889
LDHB lactate dehydrogenase B -2.07082
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -2.06385
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -2.0404
LRRN1 leucine rich repeat neuronal 1 -2.01811
VTI1B vesicle transport through interaction with t-SNAREs 1B -2.01201
SASS6 spindle assembly 6 homolog (C. elegans) -2.00794
RFK riboflavin kinase -2.00257
DGAT2 diacylglycerol O-acyltransferase 2 -1.99855
SPRYD7 SPRY domain containing 7 -1.98438
TRIM13 tripartite motif containing 13 -1.9709
SPERT spermatid associated -1.96259
COMMD9 COMM domain containing 9 -1.95742
LRP1B low density lipoprotein receptor-related protein 1B -1.95152
TMBIM6 transmembrane BAX inhibitor motif containing 6 -1.9471
ANKRD40 ankyrin repeat domain 40 -1.94276
RCL1 RNA terminal phosphate cyclase-like 1 -1.94188
SLAIN1 SLAIN motif family, member 1 -1.93093
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -1.92831
RNF34 ring finger protein 34, E3 ubiquitin protein ligase -1.92784
MAPK10 mitogen-activated protein kinase 10 -1.92247
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -1.92177
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) -1.89805
TPI1 triosephosphate isomerase 1 -1.8914
GRK6 G protein-coupled receptor kinase 6 -1.88817
RHBDD3 rhomboid domain containing 3 -1.88688
EMC10 ER membrane protein complex subunit 10 -1.86823
IQCC IQ motif containing C -1.86663
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -1.86542
IGHMBP2 immunoglobulin mu binding protein 2 -1.8608
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -1.84792
RNF141 ring finger protein 141 -1.81975
AP2A1 adaptor-related protein complex 2, alpha 1 subunit -1.81009
RAB43 RAB43, member RAS oncogene family -1.80829
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -1.80461
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha -1.79893
PROSC proline synthetase co-transcribed homolog (bacterial) -1.79889
EIF4B eukaryotic translation initiation factor 4B -1.79486
KIF17 kinesin family member 17 -1.76965
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 -1.7646
NTSR2 neurotensin receptor 2 -1.75617
INTS7 integrator complex subunit 7 -1.75015
SESN3 sestrin 3 -1.73337
SCN1B sodium channel, voltage gated, type I beta subunit -1.73096
STX18 syntaxin 18 -1.72692
APLN apelin -1.72166
SYF2 SYF2 pre-mRNA-splicing factor -1.71322
PIM2 Pim-2 proto-oncogene, serine/threonine kinase -1.70502
CTSZ cathepsin Z -1.70114
FA2H fatty acid 2-hydroxylase -1.69907
FBXL20 F-box and leucine-rich repeat protein 20 -1.69419
RAB4B RAB4B, member RAS oncogene family -1.69218
FBXO33 F-box protein 33 -1.68089
GALT galactose-1-phosphate uridylyltransferase -1.67525
OAZ1 ornithine decarboxylase antizyme 1 -1.67259
ANKRD46 ankyrin repeat domain 46 -1.66029
RTN4 reticulon 4 -1.65123
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 -1.6491
TPD52 tumor protein D52 -1.63918
CRK v-crk avian sarcoma virus CT10 oncogene homolog -1.6301
PFKM phosphofructokinase, muscle -1.62434
MDH1 malate dehydrogenase 1, NAD (soluble) -1.60751
ANKH ANKH inorganic pyrophosphate transport regulator -1.6055
FLT1 fms-related tyrosine kinase 1 -1.60506
HIST1H3G histone cluster 1, H3g -1.60312
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 -1.60136
TM2D2 TM2 domain containing 2 -1.59803
CSF1R colony stimulating factor 1 receptor -1.58873
EIF5 eukaryotic translation initiation factor 5 -1.58762
TMEM110-MUSTN1 TMEM110-MUSTN1 readthrough -1.57488
GNAS GNAS complex locus -1.57391
EPDR1 ependymin related 1 -1.5671
NFIX nuclear factor I/X (CCAAT-binding transcription factor) -1.56689
HMGN1 high mobility group nucleosome binding domain 1 -1.56221
EFNB3 ephrin-B3 -1.55354
LEPROTL1 leptin receptor overlapping transcript-like 1 -1.54517
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 -1.54135
ZNF296 zinc finger protein 296 -1.54094
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -1.51787
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) -1.51419
TESK2 testis-specific kinase 2 -1.51373
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -1.5007
GPI glucose-6-phosphate isomerase -1.50012
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -1.49826
LDLRAP1 low density lipoprotein receptor adaptor protein 1 -1.49697
TRAP1 TNF receptor-associated protein 1 -1.49311
NONO non-POU domain containing, octamer-binding -1.48615
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) -1.48021
SEPT4 septin 4 -1.47966
NARF nuclear prelamin A recognition factor -1.4747
ZBTB2 zinc finger and BTB domain containing 2 -1.47308
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 -1.46419
LITAF lipopolysaccharide-induced TNF factor -1.45894
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 -1.45878
PPIA peptidylprolyl isomerase A (cyclophilin A) -1.45772
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -1.4572
MCEE methylmalonyl CoA epimerase -1.44248
C21ORF91 chromosome 21 open reading frame 91 -1.43711
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -1.43007
FAM103A1 family with sequence similarity 103, member A1 -1.42736
SH3GL2 SH3-domain GRB2-like 2 -1.41802
DYNLRB1 dynein, light chain, roadblock-type 1 -1.41776
ADA adenosine deaminase -1.4136
SIGLEC8 sialic acid binding Ig-like lectin 8 -1.40839
ITGB4 integrin, beta 4 -1.40781
ALPK3 alpha-kinase 3 -1.4057
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) -1.40451
CA2 carbonic anhydrase II -1.40356
USP25 ubiquitin specific peptidase 25 -1.40338
DDRGK1 DDRGK domain containing 1 -1.40228
CCDC134 coiled-coil domain containing 134 -1.39505
JTB jumping translocation breakpoint -1.39318
STARD10 StAR-related lipid transfer (START) domain containing 10 -1.38389
MRPL46 mitochondrial ribosomal protein L46 -1.37546
FBLN1 fibulin 1 -1.37418
DUSP1 dual specificity phosphatase 1 -1.36741
TTI1 TELO2 interacting protein 1 -1.36734
TEX264 testis expressed 264 -1.36531
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) -1.36368
HOXB5 homeobox B5 -1.36065
TPRN taperin -1.3606
SDCBP syndecan binding protein (syntenin) -1.35645
PEG10 paternally expressed 10 -1.34746
BCAT1 branched chain amino-acid transaminase 1, cytosolic -1.34389
KIAA1407 KIAA1407 -1.32171
FGFR2 fibroblast growth factor receptor 2 -1.32092
AR androgen receptor -1.32026
BCAP31 B-cell receptor-associated protein 31 -1.31536
PPID peptidylprolyl isomerase D -1.31219
THY1 Thy-1 cell surface antigen -1.30602
LYPLA2 lysophospholipase II -1.30472
GABARAPL2 GABA(A) receptor-associated protein-like 2 -1.30214
NDUFA4 NDUFA4, mitochondrial complex associated -1.29077
SNW1 SNW domain containing 1 -1.28831
PCSK6 proprotein convertase subtilisin/kexin type 6 -1.2883
CES4A carboxylesterase 4A -1.2857
ASCC1 activating signal cointegrator 1 complex subunit 1 -1.27818
VDAC2 voltage-dependent anion channel 2 -1.27786
GAB1 GRB2-associated binding protein 1 -1.27616
OXT oxytocin/neurophysin I prepropeptide -1.27202
DEGS1 delta(4)-desaturase, sphingolipid 1 -1.27019
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -1.2673
ALDOA aldolase A, fructose-bisphosphate -1.26729
ABHD12 abhydrolase domain containing 12 -1.26632
MACROD1 MACRO domain containing 1 -1.26468
SYT3 synaptotagmin III -1.26408
ACO2 aconitase 2, mitochondrial -1.26164
TULP4 tubby like protein 4 -1.25903
SPRYD3 SPRY domain containing 3 -1.25693
PTX3 pentraxin 3, long -1.25648
FXYD4 FXYD domain containing ion transport regulator 4 -1.25454
RANBP3 RAN binding protein 3 -1.25095
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y -1.25006
KANK3 KN motif and ankyrin repeat domains 3 -1.24902
ABHD4 abhydrolase domain containing 4 -1.24837
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -1.24824
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta -1.24604
ZFP64 ZFP64 zinc finger protein -1.24496
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -1.24127
RPL3 ribosomal protein L3 -1.24031
KL klotho -1.23952
IFT80 intraflagellar transport 80 -1.23847
FAM134C family with sequence similarity 134, member C -1.2382
CRNKL1 crooked neck pre-mRNA splicing factor 1 -1.23294
EEF1G eukaryotic translation elongation factor 1 gamma -1.22766
TMEM30A transmembrane protein 30A -1.22374
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -1.21869
ACOT13 acyl-CoA thioesterase 13 -1.21765
TXNDC16 thioredoxin domain containing 16 -1.2166
EVX2 even-skipped homeobox 2 -1.21605
AK1 adenylate kinase 1 -1.21435
CCNG2 cyclin G2 -1.20862
JUN jun proto-oncogene -1.20578
SPARCL1 SPARC-like 1 (hevin) -1.20354
CEND1 cell cycle exit and neuronal differentiation 1 -1.1989
DMP1 dentin matrix acidic phosphoprotein 1 -1.19821
C2ORF71 chromosome 2 open reading frame 71 -1.19777
MYO1G myosin IG -1.19703
EEF2 eukaryotic translation elongation factor 2 -1.19516
HDGF hepatoma-derived growth factor -1.18745
MIXL1 Mix paired-like homeobox -1.18521
RNF130 ring finger protein 130 -1.18301
AK3 adenylate kinase 3 -1.18135
MICU1 mitochondrial calcium uptake 1 -1.18066
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -1.17914
DLG1 discs, large homolog 1 (Drosophila) -1.17219
C10ORF54 chromosome 10 open reading frame 54 -1.16408
TOR1AIP1 torsin A interacting protein 1 -1.16229
GNB5 guanine nucleotide binding protein (G protein), beta 5 -1.15761
RGS8 regulator of G-protein signaling 8 -1.15742
HSPB8 heat shock 22kDa protein 8 -1.15604
DPCD deleted in primary ciliary dyskinesia homolog (mouse) -1.14947
MSRA methionine sulfoxide reductase A -1.14874
RASL11B RAS-like, family 11, member B -1.14728
RPL26 ribosomal protein L26 -1.14513
OLIG1 oligodendrocyte transcription factor 1 -1.1449
ZFP57 ZFP57 zinc finger protein -1.14316
SLC22A25 solute carrier family 22, member 25 -1.14164
GABARAPL1 GABA(A) receptor-associated protein like 1 -1.13937
HSPH1 heat shock 105kDa/110kDa protein 1 -1.13601
PRNP prion protein -1.1355
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 -1.13388
GLIS2 GLIS family zinc finger 2 -1.13152
CARD10 caspase recruitment domain family, member 10 -1.125
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -1.12496
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2 -1.1236
TRAPPC2 trafficking protein particle complex 2 -1.12356
FAM134B family with sequence similarity 134, member B -1.11093
GSTK1 glutathione S-transferase kappa 1 -1.10636
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -1.10565
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 -1.10149
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -1.10119
PLEKHO2 pleckstrin homology domain containing, family O member 2 -1.10066
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) -1.09985
DEXI Dexi homolog (mouse) -1.09817
PRSS22 protease, serine, 22 -1.09795
ANXA5 annexin A5 -1.09327
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q -1.09295
TSC22D3 TSC22 domain family, member 3 -1.09236
MRPL27 mitochondrial ribosomal protein L27 -1.09192
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -1.09107
MBP myelin basic protein -1.09029
AHCY adenosylhomocysteinase -1.09019
ANXA2 annexin A2 -1.08715
PEX13 peroxisomal biogenesis factor 13 -1.08651
NMT1 N-myristoyltransferase 1 -1.08508
MYO1D myosin ID -1.08457
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 -1.08133
HPS3 Hermansky-Pudlak syndrome 3 -1.07961
FAM120B family with sequence similarity 120B -1.07423
PKLR pyruvate kinase, liver and RBC -1.07311
KHK ketohexokinase (fructokinase) -1.07116
NFS1 NFS1 cysteine desulfurase -1.07005
CD81 CD81 molecule -1.06746
PPCDC phosphopantothenoylcysteine decarboxylase -1.06598
LRP10 low density lipoprotein receptor-related protein 10 -1.06493
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -1.06379
ASB6 ankyrin repeat and SOCS box containing 6 -1.06074
CTSD cathepsin D -1.05669
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.05635
PHGDH phosphoglycerate dehydrogenase -1.05443
STMN4 stathmin-like 4 -1.05377
TFF3 trefoil factor 3 (intestinal) -1.05358
TYROBP TYRO protein tyrosine kinase binding protein -1.05202
CLDN14 claudin 14 -1.04788
NSF N-ethylmaleimide-sensitive factor -1.0478
PLIN3 perilipin 3 -1.04672
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae) -1.04633
PEA15 phosphoprotein enriched in astrocytes 15 -1.04327