Small Cell Lung Carcinoma Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

102 genes associated with the Small Cell Lung Carcinoma phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
AQP2 aquaporin 2 (collecting duct)
AQP9 aquaporin 9
ATM ATM serine/threonine kinase
BCL2 B-cell CLL/lymphoma 2
BCR breakpoint cluster region
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTBD3 BTB (POZ) domain containing 3
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLPTM1L CLPTM1-like
CMBL carboxymethylenebutenolidase homolog (Pseudomonas)
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
EGFR epidermal growth factor receptor
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ERCC1 excision repair cross-complementation group 1
EXO1 exonuclease 1
EXOC2 exocyst complex component 2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FOLR1 folate receptor 1 (adult)
FOS FBJ murine osteosarcoma viral oncogene homolog
FPGS folylpolyglutamate synthase
GCLC glutamate-cysteine ligase, catalytic subunit
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GSTA4 glutathione S-transferase alpha 4
GSTP1 glutathione S-transferase pi 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HORMAD2 HORMA domain containing 2
HSPA1B heat shock 70kDa protein 1B
HSPB1 heat shock 27kDa protein 1
HYKK hydroxylysine kinase
IFNG interferon, gamma
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
IRF4 interferon regulatory factor 4
JUN jun proto-oncogene
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRAS Kirsten rat sarcoma viral oncogene homolog
LIF leukemia inhibitory factor
MAP2K1 mitogen-activated protein kinase kinase 1
MBD4 methyl-CpG binding domain protein 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR3 myotubularin related protein 3
MVP major vault protein
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NQO1 NAD(P)H dehydrogenase, quinone 1
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OPN3 opsin 3
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRRC2A proline-rich coiled-coil 2A
PTEN phosphatase and tensin homolog
RAB3D RAB3D, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
REV1 REV1, polymerase (DNA directed)
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIPA1 signal-induced proliferation-associated 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
STXBP5 syntaxin binding protein 5 (tomosyn)
SYNE3 spectrin repeat containing, nuclear envelope family member 3
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TMEM205 transmembrane protein 205
TNF tumor necrosis factor
TP53 tumor protein p53
TYMS thymidylate synthetase
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VEGFA vascular endothelial growth factor A
WDR64 WD repeat domain 64
WWOX WW domain containing oxidoreductase