SCID - Severe combined immunodeficiency_Lung Tissue_GSE3414 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE3414
Similar Terms
Downloads & Tools

Genes

600 genes differentially expressed during SCID - Severe combined immunodeficiency_Lung Tissue_GSE3414 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
FYCO1 FYVE and coiled-coil domain containing 1 4.27744
EHD2 EH-domain containing 2 4.22877
B3GNT1 4.0939
ELOVL5 ELOVL fatty acid elongase 5 3.99665
GPRASP1 G protein-coupled receptor associated sorting protein 1 3.64069
TJP1 tight junction protein 1 3.57278
SKA2 spindle and kinetochore associated complex subunit 2 3.52724
SUMO1 small ubiquitin-like modifier 1 3.49055
SLIT2 slit homolog 2 (Drosophila) 3.47
FOXK2 forkhead box K2 3.30466
MRRF mitochondrial ribosome recycling factor 3.16403
IL1A interleukin 1, alpha 3.15904
HDAC3 histone deacetylase 3 3.11475
GFPT2 glutamine-fructose-6-phosphate transaminase 2 3.10236
GLRX5 glutaredoxin 5 3.02552
SMAD1 SMAD family member 1 3.01389
MCM7 minichromosome maintenance complex component 7 2.97689
ANKRD46 ankyrin repeat domain 46 2.89987
TPPP tubulin polymerization promoting protein 2.82653
CD38 CD38 molecule 2.785
PROS1 protein S (alpha) 2.77038
TMEM57 transmembrane protein 57 2.76654
STARD5 StAR-related lipid transfer (START) domain containing 5 2.75966
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 2.71359
APTX aprataxin 2.64008
VPS37A vacuolar protein sorting 37 homolog A (S. cerevisiae) 2.60237
CDYL2 chromodomain protein, Y-like 2 2.54137
USP46 ubiquitin specific peptidase 46 2.52161
ZNF878 zinc finger protein 878 2.49669
IREB2 iron-responsive element binding protein 2 2.47381
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1 2.40008
MANSC1 MANSC domain containing 1 2.39869
SOD2 superoxide dismutase 2, mitochondrial 2.39194
SELK selenoprotein K 2.38323
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2.36508
DPY19L4 dpy-19-like 4 (C. elegans) 2.35324
ZNF526 zinc finger protein 526 2.34849
TMEM231 transmembrane protein 231 2.33896
COLEC12 collectin sub-family member 12 2.33805
PKNOX2 PBX/knotted 1 homeobox 2 2.3202
PTPN3 protein tyrosine phosphatase, non-receptor type 3 2.31644
USP45 ubiquitin specific peptidase 45 2.30699
TDGF1 teratocarcinoma-derived growth factor 1 2.29114
MAL mal, T-cell differentiation protein 2.27983
ING3 inhibitor of growth family, member 3 2.27818
WISP2 WNT1 inducible signaling pathway protein 2 2.27421
MOSPD2 motile sperm domain containing 2 2.22173
HDAC1 histone deacetylase 1 2.22058
TLR6 toll-like receptor 6 2.20612
PLCE1 phospholipase C, epsilon 1 2.19158
FBXL20 F-box and leucine-rich repeat protein 20 2.1711
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 2.17069
DNPEP aspartyl aminopeptidase 2.12274
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 2.11565
CTGF connective tissue growth factor 2.11133
PKD1 polycystic kidney disease 1 (autosomal dominant) 2.07707
TSPAN2 tetraspanin 2 2.07191
TEK TEK tyrosine kinase, endothelial 2.07088
NRD1 nardilysin (N-arginine dibasic convertase) 2.07018
ZNF354A zinc finger protein 354A 2.06982
FZD6 frizzled class receptor 6 2.06554
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.05607
COG6 component of oligomeric golgi complex 6 2.0459
VIM vimentin 2.02661
FRMD4B FERM domain containing 4B 2.02338
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 2.01135
DCTN3 dynactin 3 (p22) 2.00884
PRKD1 protein kinase D1 1.99911
BTBD3 BTB (POZ) domain containing 3 1.99221
LZTFL1 leucine zipper transcription factor-like 1 1.99003
LOC646862 1.94705
PEF1 penta-EF-hand domain containing 1 1.94531
HINT3 histidine triad nucleotide binding protein 3 1.94325
PRPF4 pre-mRNA processing factor 4 1.94047
ARRDC3 arrestin domain containing 3 1.9379
COL4A5 collagen, type IV, alpha 5 1.93779
SH3TC2 SH3 domain and tetratricopeptide repeats 2 1.93304
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 1.91906
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.90857
THBD thrombomodulin 1.88643
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 1.87859
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 1.87654
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 1.87573
GTF2IRD1 GTF2I repeat domain containing 1 1.87526
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 1.8687
NR2F6 nuclear receptor subfamily 2, group F, member 6 1.8661
SVIL supervillin 1.85769
RPAIN RPA interacting protein 1.85624
APLN apelin 1.8489
PGGT1B protein geranylgeranyltransferase type I, beta subunit 1.82521
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.81516
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 1.81501
LTBP2 latent transforming growth factor beta binding protein 2 1.80321
FNTA farnesyltransferase, CAAX box, alpha 1.80256
ZNF446 zinc finger protein 446 1.79874
RAB19 RAB19, member RAS oncogene family 1.79206
GLG1 golgi glycoprotein 1 1.75586
SCARB2 scavenger receptor class B, member 2 1.74742
PTPRM protein tyrosine phosphatase, receptor type, M 1.73434
AGFG1 ArfGAP with FG repeats 1 1.73237
MMGT1 membrane magnesium transporter 1 1.73186
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.72928
XBP1 X-box binding protein 1 1.7287
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.71917
IRF2BP2 interferon regulatory factor 2 binding protein 2 1.71545
TSLP thymic stromal lymphopoietin 1.69867
PICALM phosphatidylinositol binding clathrin assembly protein 1.69751
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like 1.69599
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 1.68543
WFDC1 WAP four-disulfide core domain 1 1.68013
ADGRL4 adhesion G protein-coupled receptor L4 1.67477
GNA14 guanine nucleotide binding protein (G protein), alpha 14 1.67061
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.67008
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) 1.67002
TSHZ1 teashirt zinc finger homeobox 1 1.66551
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 1.66343
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 1.65382
BTBD1 BTB (POZ) domain containing 1 1.63891
ISM1 isthmin 1, angiogenesis inhibitor 1.63433
POSTN periostin, osteoblast specific factor 1.63058
SLCO5A1 solute carrier organic anion transporter family, member 5A1 1.62395
PDCL phosducin-like 1.622
FIG4 FIG4 phosphoinositide 5-phosphatase 1.61652
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) 1.61325
IDE insulin-degrading enzyme 1.60618
TSPAN4 tetraspanin 4 1.60315
MFAP1 microfibrillar-associated protein 1 1.58803
TCF4 transcription factor 4 1.58706
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 1.57987
VAMP4 vesicle-associated membrane protein 4 1.57328
CTIF CBP80/20-dependent translation initiation factor 1.56777
FAM171A1 family with sequence similarity 171, member A1 1.56405
PFDN5 prefoldin subunit 5 1.55657
FADS1 fatty acid desaturase 1 1.53993
MXRA8 matrix-remodelling associated 8 1.53952
NR2F1 nuclear receptor subfamily 2, group F, member 1 1.5372
HIGD1B HIG1 hypoxia inducible domain family, member 1B 1.53443
TEX15 testis expressed 15 1.52619
ZNF519 zinc finger protein 519 1.52366
RBP7 retinol binding protein 7, cellular 1.51839
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 1.51704
MCM4 minichromosome maintenance complex component 4 1.51661
FKBP7 FK506 binding protein 7 1.51305
FAM110C family with sequence similarity 110, member C 1.51248
PPP1R35 protein phosphatase 1, regulatory subunit 35 1.50658
TCF19 transcription factor 19 1.50563
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 1.50491
GOLGA5 golgin A5 1.50446
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 1.5002
ARMCX2 armadillo repeat containing, X-linked 2 1.49818
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 1.48954
TXN thioredoxin 1.4883
MFSD6L major facilitator superfamily domain containing 6-like 1.48677
USP54 ubiquitin specific peptidase 54 1.48676
GSTA3 glutathione S-transferase alpha 3 1.48584
TRIM27 tripartite motif containing 27 1.47679
PKD2 polycystic kidney disease 2 (autosomal dominant) 1.47044
USF2 upstream transcription factor 2, c-fos interacting 1.46944
LONRF1 LON peptidase N-terminal domain and ring finger 1 1.46255
QPCTL glutaminyl-peptide cyclotransferase-like 1.46164
GLUL glutamate-ammonia ligase 1.45795
ATRN attractin 1.45118
BRDT bromodomain, testis-specific 1.44729
GBE1 glucan (1,4-alpha-), branching enzyme 1 1.44688
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 1.44558
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.43256
KLHL18 kelch-like family member 18 1.43191
UBIAD1 UbiA prenyltransferase domain containing 1 1.42725
PFDN1 prefoldin subunit 1 1.42406
DPP4 dipeptidyl-peptidase 4 1.42204
MTMR6 myotubularin related protein 6 1.41594
COL6A3 collagen, type VI, alpha 3 1.41235
TSPAN3 tetraspanin 3 1.4073
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 1.40489
CLIC4 chloride intracellular channel 4 1.39928
UBE2E1 ubiquitin-conjugating enzyme E2E 1 1.39722
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) 1.39679
SF3B4 splicing factor 3b, subunit 4, 49kDa 1.39257
KCTD21 potassium channel tetramerization domain containing 21 1.38932
BFAR bifunctional apoptosis regulator 1.38474
SEC11A SEC11 homolog A (S. cerevisiae) 1.38386
ECHDC1 ethylmalonyl-CoA decarboxylase 1 1.38331
FKBP9 FK506 binding protein 9, 63 kDa 1.38269
AP1AR adaptor-related protein complex 1 associated regulatory protein 1.38245
ZFP37 ZFP37 zinc finger protein 1.38202
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.37165
EML6 echinoderm microtubule associated protein like 6 1.3694
FAM151B family with sequence similarity 151, member B 1.36254
DCBLD1 discoidin, CUB and LCCL domain containing 1 1.35743
DCAF17 DDB1 and CUL4 associated factor 17 1.35561
ASPHD2 aspartate beta-hydroxylase domain containing 2 1.35221
TPRN taperin 1.35093
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.34153
MRPL13 mitochondrial ribosomal protein L13 1.34023
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1 1.33061
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 1.3302
WBSCR28 Williams-Beuren syndrome chromosome region 28 1.32325
BAD BCL2-associated agonist of cell death 1.31543
C2CD4B C2 calcium-dependent domain containing 4B 1.30954
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 1.3004
IL6ST interleukin 6 signal transducer 1.2996
COPS4 COP9 signalosome subunit 4 1.29782
ARHGAP20 Rho GTPase activating protein 20 1.29724
PITRM1 pitrilysin metallopeptidase 1 1.29704
TTC23 tetratricopeptide repeat domain 23 1.29388
ELAVL1 ELAV like RNA binding protein 1 1.29319
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.29269
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 1.29109
ZNF426 zinc finger protein 426 1.28797
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 1.2744
PLSCR4 phospholipid scramblase 4 1.27374
PTP4A1 protein tyrosine phosphatase type IVA, member 1 1.2548
PHLDB2 pleckstrin homology-like domain, family B, member 2 1.2544
SEPP1 selenoprotein P, plasma, 1 1.25353
SPAG9 sperm associated antigen 9 1.25034
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 1.24182
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 1.24178
MPEG1 macrophage expressed 1 1.24143
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 1.24082
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 1.23104
PAQR4 progestin and adipoQ receptor family member IV 1.22991
ARFRP1 ADP-ribosylation factor related protein 1 1.2296
NDFIP1 Nedd4 family interacting protein 1 1.22805
COL14A1 collagen, type XIV, alpha 1 1.22725
KBTBD3 kelch repeat and BTB (POZ) domain containing 3 1.22194
PCYOX1 prenylcysteine oxidase 1 1.22178
SET SET nuclear proto-oncogene 1.22047
NUBP2 nucleotide binding protein 2 1.21766
TRIL TLR4 interactor with leucine-rich repeats 1.21516
RPUSD1 RNA pseudouridylate synthase domain containing 1 1.21341
PSPH phosphoserine phosphatase 1.21118
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.20639
HAGH hydroxyacylglutathione hydrolase 1.20444
TRPC3 transient receptor potential cation channel, subfamily C, member 3 1.20413
BICC1 BicC family RNA binding protein 1 1.20348
MGP matrix Gla protein 1.1962
EI24 etoposide induced 2.4 1.19613
FYTTD1 forty-two-three domain containing 1 1.1948
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 1.19444
ARFGEF3 ARFGEF family member 3 1.19238
CADPS2 Ca++-dependent secretion activator 2 1.18979
CA8 carbonic anhydrase VIII 1.18636
FAM198B family with sequence similarity 198, member B 1.18464
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 1.18408
MBNL2 muscleblind-like splicing regulator 2 1.18389
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 1.18284
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 1.18196
SAT1 spermidine/spermine N1-acetyltransferase 1 1.18098
CRNKL1 crooked neck pre-mRNA splicing factor 1 1.18077
HOXA5 homeobox A5 1.1762
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 1.1747
PKP4 plakophilin 4 1.17372
STEAP2 STEAP family member 2, metalloreductase 1.17014
SYAP1 synapse associated protein 1 1.1699
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 1.16884
TMOD1 tropomodulin 1 1.16675
EFR3A EFR3 homolog A (S. cerevisiae) 1.16245
TSPAN8 tetraspanin 8 1.16217
SNX18 sorting nexin 18 1.16171
PIGX phosphatidylinositol glycan anchor biosynthesis, class X 1.16094
ATG5 autophagy related 5 1.15933
DRAM2 DNA-damage regulated autophagy modulator 2 1.15764
FUCA2 fucosidase, alpha-L- 2, plasma 1.15725
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 1.15649
ALOX5 arachidonate 5-lipoxygenase 1.15577
PDCL3 phosducin-like 3 1.15215
STX7 syntaxin 7 1.15141
CNKSR3 CNKSR family member 3 1.14953
DOHH deoxyhypusine hydroxylase/monooxygenase 1.14862
ITM2C integral membrane protein 2C 1.14774
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 1.14587
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 1.14131
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.13673
BCL2L2 BCL2-like 2 1.13452
AAK1 AP2 associated kinase 1 1.13062
GSR glutathione reductase 1.12747
AKAP5 A kinase (PRKA) anchor protein 5 1.12424
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 1.12399
RNF214 ring finger protein 214 1.12265
RAB22A RAB22A, member RAS oncogene family 1.12265
AIM1L absent in melanoma 1-like 1.1222
GDAP1L1 ganglioside induced differentiation associated protein 1-like 1 1.11912
WDR26 WD repeat domain 26 1.11802
TBCA tubulin folding cofactor A 1.11533
PPAP2B phosphatidic acid phosphatase type 2B 1.11417
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 1.11203
UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast) 1.10625
GAB2 GRB2-associated binding protein 2 1.10436
FGFRL1 fibroblast growth factor receptor-like 1 1.10307
CD34 CD34 molecule 1.10292
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 1.10266
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 1.10185
TMEM45A transmembrane protein 45A 1.10151
CADM1 cell adhesion molecule 1 1.10059
ITM2A integral membrane protein 2A 1.1004
CPT1A carnitine palmitoyltransferase 1A (liver) 1.09884
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 1.09856
ABHD14A abhydrolase domain containing 14A 1.09628
PALMD palmdelphin 1.09395
NRXN1 neurexin 1 1.09101

decreased expression

Symbol Name Standardized Value
PDGFRB platelet-derived growth factor receptor, beta polypeptide -4.29265
IRAK2 interleukin-1 receptor-associated kinase 2 -3.93627
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 -3.6734
AKAP8 A kinase (PRKA) anchor protein 8 -3.59527
C5ORF30 chromosome 5 open reading frame 30 -3.54498
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -3.48792
BLNK B-cell linker -3.4476
RPL4 ribosomal protein L4 -3.39585
LRTM1 leucine-rich repeats and transmembrane domains 1 -3.33953
PTPRF protein tyrosine phosphatase, receptor type, F -3.23832
STX16 syntaxin 16 -3.18578
RPIA ribose 5-phosphate isomerase A -3.12965
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.12403
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 -3.09789
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit -3.09657
KATNA1 katanin p60 (ATPase containing) subunit A 1 -3.07394
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -2.94833
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.93677
SIRT7 sirtuin 7 -2.898
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa -2.88599
GPS2 G protein pathway suppressor 2 -2.83565
PHYH phytanoyl-CoA 2-hydroxylase -2.82363
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -2.76461
LIMD1 LIM domains containing 1 -2.74766
KCTD9 potassium channel tetramerization domain containing 9 -2.73409
RNF8 ring finger protein 8, E3 ubiquitin protein ligase -2.70419
EPHA7 EPH receptor A7 -2.66507
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein -2.65754
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -2.64579
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -2.63683
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -2.60456
GPR18 G protein-coupled receptor 18 -2.57052
UBXN1 UBX domain protein 1 -2.537
ZFX zinc finger protein, X-linked -2.52199
CPM carboxypeptidase M -2.5096
SH3BP1 SH3-domain binding protein 1 -2.50676
IMMT inner membrane protein, mitochondrial -2.47572
C16ORF54 chromosome 16 open reading frame 54 -2.44911
DPEP1 dipeptidase 1 (renal) -2.42653
LAX1 lymphocyte transmembrane adaptor 1 -2.42378
VGLL3 vestigial-like family member 3 -2.42046
CARD11 caspase recruitment domain family, member 11 -2.42008
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -2.39542
DGKG diacylglycerol kinase, gamma 90kDa -2.39142
JARID2 jumonji, AT rich interactive domain 2 -2.3769
NCOA2 nuclear receptor coactivator 2 -2.36666
MYO18A myosin XVIIIA -2.35609
CCM2 cerebral cavernous malformation 2 -2.29092
MMP14 matrix metallopeptidase 14 (membrane-inserted) -2.28057
GRAP2 GRB2-related adaptor protein 2 -2.26453
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -2.26264
BEX4 brain expressed, X-linked 4 -2.25882
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.25602
CYTIP cytohesin 1 interacting protein -2.2416
MAP2K1 mitogen-activated protein kinase kinase 1 -2.21974
PCGF6 polycomb group ring finger 6 -2.21699
VWA8 von Willebrand factor A domain containing 8 -2.19083
KDR kinase insert domain receptor -2.17366
DOCK2 dedicator of cytokinesis 2 -2.15308
NAT6 N-acetyltransferase 6 (GCN5-related) -2.14144
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -2.13998
PHGDH phosphoglycerate dehydrogenase -2.10425
ZNHIT6 zinc finger, HIT-type containing 6 -2.09601
NXF1 nuclear RNA export factor 1 -2.07407
TRIM26 tripartite motif containing 26 -2.07278
CLN5 ceroid-lipofuscinosis, neuronal 5 -2.06393
ZNF18 zinc finger protein 18 -2.0575
NCEH1 neutral cholesterol ester hydrolase 1 -2.04514
TMEM183A transmembrane protein 183A -2.04513
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.04095
CCDC115 coiled-coil domain containing 115 -2.03969
SERTAD2 SERTA domain containing 2 -2.03923
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 -2.02351
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.99712
GPI glucose-6-phosphate isomerase -1.99364
STARD10 StAR-related lipid transfer (START) domain containing 10 -1.97999
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 -1.97824
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -1.94755
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -1.94668
BAIAP2L1 BAI1-associated protein 2-like 1 -1.9431
SRSF4 serine/arginine-rich splicing factor 4 -1.93239
WDR4 WD repeat domain 4 -1.92524
STX2 syntaxin 2 -1.91652
UNKL unkempt family zinc finger-like -1.91193
TMEM19 transmembrane protein 19 -1.89497
DONSON downstream neighbor of SON -1.8928
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 -1.88694
TRRAP transformation/transcription domain-associated protein -1.86931
PXK PX domain containing serine/threonine kinase -1.85802
SH3GLB2 SH3-domain GRB2-like endophilin B2 -1.85744
CYB5R1 cytochrome b5 reductase 1 -1.84569
HABP4 hyaluronan binding protein 4 -1.84457
KLHL17 kelch-like family member 17 -1.84067
PANK4 pantothenate kinase 4 -1.83256
FNBP1 formin binding protein 1 -1.82716
MED12 mediator complex subunit 12 -1.81977
THOC6 THO complex 6 -1.81168
HSDL1 hydroxysteroid dehydrogenase like 1 -1.8052
SFI1 Sfi1 homolog, spindle assembly associated (yeast) -1.79986
GLO1 glyoxalase I -1.79667
HACD3 3-hydroxyacyl-CoA dehydratase 3 -1.78923
IPO4 importin 4 -1.78483
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -1.75724
EDNRA endothelin receptor type A -1.75318
CTHRC1 collagen triple helix repeat containing 1 -1.74199
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -1.73413
CCDC28B coiled-coil domain containing 28B -1.7305
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -1.72732
ADGRE5 adhesion G protein-coupled receptor E5 -1.72217
NR1D1 nuclear receptor subfamily 1, group D, member 1 -1.71921
LBR lamin B receptor -1.71328
PGD phosphogluconate dehydrogenase -1.71227
TMEM161B transmembrane protein 161B -1.70897
NECAP2 NECAP endocytosis associated 2 -1.70849
HOPX HOP homeobox -1.705
TSEN54 TSEN54 tRNA splicing endonuclease subunit -1.70059
CD79B CD79b molecule, immunoglobulin-associated beta -1.68053
ADPRHL2 ADP-ribosylhydrolase like 2 -1.67729
EPS8L2 EPS8-like 2 -1.67639
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 -1.66085
COX5A cytochrome c oxidase subunit Va -1.66016
SF3B1 splicing factor 3b, subunit 1, 155kDa -1.65678
CD19 CD19 molecule -1.65365
TP53BP2 tumor protein p53 binding protein 2 -1.65118
RARS2 arginyl-tRNA synthetase 2, mitochondrial -1.65069
TMBIM4 transmembrane BAX inhibitor motif containing 4 -1.64731
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -1.64643
ISCA2 iron-sulfur cluster assembly 2 -1.63932
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha -1.63401
N4BP2L1 NEDD4 binding protein 2-like 1 -1.62884
AMPH amphiphysin -1.62843
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -1.61689
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -1.60837
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -1.60826
C14ORF1 chromosome 14 open reading frame 1 -1.60796
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 -1.60546
CENPV centromere protein V -1.6024
C6ORF203 chromosome 6 open reading frame 203 -1.59946
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -1.5937
EDC4 enhancer of mRNA decapping 4 -1.59362
CETN2 centrin, EF-hand protein, 2 -1.58994
NEK6 NIMA-related kinase 6 -1.57901
UBA2 ubiquitin-like modifier activating enzyme 2 -1.57895
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B -1.57836
EHD1 EH-domain containing 1 -1.57275
MED14 mediator complex subunit 14 -1.56066
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C -1.55525
BCL2 B-cell CLL/lymphoma 2 -1.54425
FARSB phenylalanyl-tRNA synthetase, beta subunit -1.54403
MRPS21 mitochondrial ribosomal protein S21 -1.54308
HOXB5 homeobox B5 -1.53526
POLB polymerase (DNA directed), beta -1.53446
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -1.53307
FAAH fatty acid amide hydrolase -1.52853
NADK NAD kinase -1.52662
TRUB2 TruB pseudouridine (psi) synthase family member 2 -1.51896
NIPSNAP1 nipsnap homolog 1 (C. elegans) -1.51347
SLC30A2 solute carrier family 30 (zinc transporter), member 2 -1.5116
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -1.50996
FAM8A1 family with sequence similarity 8, member A1 -1.50873
SBK1 SH3 domain binding kinase 1 -1.50855
FGFBP1 fibroblast growth factor binding protein 1 -1.50736
DGKA diacylglycerol kinase, alpha 80kDa -1.50724
NAP1L1 nucleosome assembly protein 1-like 1 -1.50664
C11ORF58 chromosome 11 open reading frame 58 -1.50591
WDR35 WD repeat domain 35 -1.5054
SLC39A11 solute carrier family 39, member 11 -1.49865
BANK1 B-cell scaffold protein with ankyrin repeats 1 -1.49445
AARS alanyl-tRNA synthetase -1.4857
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26 -1.48396
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 -1.47557
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -1.47437
MRPS23 mitochondrial ribosomal protein S23 -1.47105
KLC2 kinesin light chain 2 -1.46574
LRRN4 leucine rich repeat neuronal 4 -1.4636
ELOF1 elongation factor 1 homolog (S. cerevisiae) -1.46324
EXOSC8 exosome component 8 -1.46196
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -1.46007
USP19 ubiquitin specific peptidase 19 -1.45656
FAM126A family with sequence similarity 126, member A -1.45149
ACOT7 acyl-CoA thioesterase 7 -1.44612
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -1.44477
CD8B CD8b molecule -1.44362
GARS glycyl-tRNA synthetase -1.44359
FOXA1 forkhead box A1 -1.44235
METTL2A methyltransferase like 2A -1.43729
FUNDC1 FUN14 domain containing 1 -1.41988
SREBF1 sterol regulatory element binding transcription factor 1 -1.41954
KDM1A lysine (K)-specific demethylase 1A -1.41511
PRRC2B proline-rich coiled-coil 2B -1.40997
NUDT22 nudix (nucleoside diphosphate linked moiety X)-type motif 22 -1.40521
ZDHHC3 zinc finger, DHHC-type containing 3 -1.40383
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -1.39944
AVPI1 arginine vasopressin-induced 1 -1.39786
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -1.39731
CNOT8 CCR4-NOT transcription complex, subunit 8 -1.39635
DPY19L3 dpy-19-like 3 (C. elegans) -1.3931
SNAI2 snail family zinc finger 2 -1.38916
RNASE4 ribonuclease, RNase A family, 4 -1.38855
RHBDD1 rhomboid domain containing 1 -1.38657
RCOR2 REST corepressor 2 -1.3805
BDH2 3-hydroxybutyrate dehydrogenase, type 2 -1.37844
SH2B3 SH2B adaptor protein 3 -1.37002
CA4 carbonic anhydrase IV -1.36698
PDCD11 programmed cell death 11 -1.35772
FXYD1 FXYD domain containing ion transport regulator 1 -1.34964
LMBR1L limb development membrane protein 1-like -1.34874
ARMC3 armadillo repeat containing 3 -1.34406
ENDOU endonuclease, polyU-specific -1.34227
PRKG2 protein kinase, cGMP-dependent, type II -1.34
PLXNA1 plexin A1 -1.33673
IL17A interleukin 17A -1.33533
CCNL1 cyclin L1 -1.324
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -1.31784
GPM6A glycoprotein M6A -1.31752
EMP3 epithelial membrane protein 3 -1.31684
SEC24B SEC24 family member B -1.31324
GSTM5 glutathione S-transferase mu 5 -1.31243
S1PR4 sphingosine-1-phosphate receptor 4 -1.31012
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -1.30701
DBNL drebrin-like -1.30629
ACADVL acyl-CoA dehydrogenase, very long chain -1.30335
PRMT2 protein arginine methyltransferase 2 -1.29397
ZNF821 zinc finger protein 821 -1.29214
LDLRAP1 low density lipoprotein receptor adaptor protein 1 -1.28697
IRAK1 interleukin-1 receptor-associated kinase 1 -1.2829
GYG1 glycogenin 1 -1.28208
IL36G interleukin 36, gamma -1.28036
HIATL1 hippocampus abundant transcript-like 1 -1.27589
LDHB lactate dehydrogenase B -1.26536
ASB8 ankyrin repeat and SOCS box containing 8 -1.26528
PTPRB protein tyrosine phosphatase, receptor type, B -1.25986
PMP22 peripheral myelin protein 22 -1.25365
TCP1 t-complex 1 -1.24929
CBR1 carbonyl reductase 1 -1.24706
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase -1.24465
RPS19 ribosomal protein S19 -1.23832
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 -1.23297
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -1.23283
PBX3 pre-B-cell leukemia homeobox 3 -1.23079
COL13A1 collagen, type XIII, alpha 1 -1.23008
ZBTB24 zinc finger and BTB domain containing 24 -1.22711
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 -1.2239
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -1.21981
MEST mesoderm specific transcript -1.21886
TBC1D10C TBC1 domain family, member 10C -1.21834
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -1.2175
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 -1.21621
ITGA10 integrin, alpha 10 -1.21562
MYO5C myosin VC -1.21561
SMAP2 small ArfGAP2 -1.20904
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 -1.20717
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -1.20558
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -1.20469
REEP5 receptor accessory protein 5 -1.19864
JAK1 Janus kinase 1 -1.19555
CREG1 cellular repressor of E1A-stimulated genes 1 -1.19554
DIRAS1 DIRAS family, GTP-binding RAS-like 1 -1.19487
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -1.1906
SDC1 syndecan 1 -1.18905
SLC30A6 solute carrier family 30 (zinc transporter), member 6 -1.18897
PHF5A PHD finger protein 5A -1.1886
MAN1A1 mannosidase, alpha, class 1A, member 1 -1.18745
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -1.1836
SGPP2 sphingosine-1-phosphate phosphatase 2 -1.18335
LIMK2 LIM domain kinase 2 -1.17226
CARHSP1 calcium regulated heat stable protein 1, 24kDa -1.17178
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 -1.16903
S1PR3 sphingosine-1-phosphate receptor 3 -1.16536
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -1.16491
PARK7 parkinson protein 7 -1.16415
PHF21A PHD finger protein 21A -1.1641
CABLES2 Cdk5 and Abl enzyme substrate 2 -1.16401
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -1.16128
CD81 CD81 molecule -1.15613
GRK6 G protein-coupled receptor kinase 6 -1.15606
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -1.15524
KAT5 K(lysine) acetyltransferase 5 -1.15449
MIEN1 migration and invasion enhancer 1 -1.14999
MRPS16 mitochondrial ribosomal protein S16 -1.14313
IZUMO4 IZUMO family member 4 -1.14179
ITGB5 integrin, beta 5 -1.14024
CDKN2AIPNL CDKN2A interacting protein N-terminal like -1.13172
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 -1.13155
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit -1.13108
CTSE cathepsin E -1.13097
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -1.13007
SEPHS2 selenophosphate synthetase 2 -1.12925
EMB embigin -1.1286
ACER2 alkaline ceramidase 2 -1.1265
SFSWAP splicing factor, suppressor of white-apricot family -1.12375
C11ORF52 chromosome 11 open reading frame 52 -1.1226
WNT11 wingless-type MMTV integration site family, member 11 -1.11881
TMEM42 transmembrane protein 42 -1.11862
PRNP prion protein -1.11802
MRPS2 mitochondrial ribosomal protein S2 -1.11788
SHB Src homology 2 domain containing adaptor protein B -1.10971
SHKBP1 SH3KBP1 binding protein 1 -1.10752
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -1.10642
CD27 CD27 molecule -1.10629