Rhinitis Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip. (Human Disease Ontology, DOID_4483)
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Genes

72 genes associated with the Rhinitis phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ADAM33 ADAM metallopeptidase domain 33
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AOAH acyloxyacyl hydrolase (neutrophil)
BCAP29 B-cell receptor-associated protein 29
BDNF brain-derived neurotrophic factor
CD14 CD14 molecule
CD8A CD8a molecule
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYSLTR1 cysteinyl leukotriene receptor 1
CYSLTR2 cysteinyl leukotriene receptor 2
EBI3 Epstein-Barr virus induced 3
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FLG filaggrin
FOXP3 forkhead box P3
GATA3 GATA binding protein 3
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HDC histidine decarboxylase
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IFNG interferon, gamma
IL10 interleukin 10
IL13 interleukin 13
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL22RA1 interleukin 22 receptor, alpha 1
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IRAK4 interleukin-1 receptor-associated kinase 4
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5
LTC4S leukotriene C4 synthase
MBL2 mannose-binding lectin (protein C) 2, soluble
MET MET proto-oncogene, receptor tyrosine kinase
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MRPL4 mitochondrial ribosomal protein L4
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NPSR1 neuropeptide S receptor 1
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RYBP RING1 and YY1 binding protein
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TAS2R13 taste receptor, type 2, member 13
TAS2R20 taste receptor, type 2, member 20
TAS2R3 taste receptor, type 2, member 3
TAS2R38 taste receptor, type 2, member 38
TBXA2R thromboxane A2 receptor
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNC tenascin C
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TP73 tumor protein p73
TSLP thymic stromal lymphopoietin