Regulation of cholesterol biosynthesis by SREBP (SREBF) Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-1655829
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Genes

53 proteins participating in the Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway from the Reactome Pathways dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACACB acetyl-CoA carboxylase beta
CARM1 coactivator-associated arginine methyltransferase 1
CHD9 chromodomain helicase DNA binding protein 9
CREBBP CREB binding protein
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
ELOVL6 ELOVL fatty acid elongase 6
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
GGPS1 geranylgeranyl diphosphate synthase 1
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
KPNB1 karyopherin (importin) beta 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MBTPS1 membrane-bound transcription factor peptidase, site 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MED1 mediator complex subunit 1
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
NCOA1 nuclear receptor coactivator 1
NCOA2 nuclear receptor coactivator 2
NCOA6 nuclear receptor coactivator 6
NFYA nuclear transcription factor Y, alpha
NFYB nuclear transcription factor Y, beta
NFYC nuclear transcription factor Y, gamma
PMVK phosphomevalonate kinase
PPARA peroxisome proliferator-activated receptor alpha
RAN RAN, member RAS oncogene family
RXRA retinoid X receptor, alpha
SAR1B secretion associated, Ras related GTPase 1B
SC5D sterol-C5-desaturase
SCAP SREBF chaperone
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24A SEC24 family member A
SEC24B SEC24 family member B
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SP1 Sp1 transcription factor
SQLE squalene epoxidase
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TGS1 trimethylguanosine synthase 1
TM7SF2 transmembrane 7 superfamily member 2