Ramipril Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure. (Chemical Entities of Biological Interest Ontology, CHEBI_8774)
External Link http://ctdbase.org/detail.go?type=chem&acc=D017257
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Genes

14 genes/proteins interacting with the chemical Ramipril from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ACE angiotensin I converting enzyme
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BMP7 bone morphogenetic protein 7
CCL2 chemokine (C-C motif) ligand 2
CES1 carboxylesterase 1
KNG1 kininogen 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REN renin
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
TGFB1 transforming growth factor, beta 1