RPMI-2650 Gene Set

Dataset COSMIC Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description Human nasal septum squamous cell carinoma cell line; established from the pleural effusion of a 52-year-old man with anaplastic squamous cell carcinoma of the nasal septum in 1962. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004205)
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219 genes mutated in the RPMI-2650 cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACSM4 acyl-CoA synthetase medium-chain family member 4
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAM2 ADAM metallopeptidase domain 2
ADAM32 ADAM metallopeptidase domain 32
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADCY7 adenylate cyclase 7
ADHFE1 alcohol dehydrogenase, iron containing, 1
AGXT alanine-glyoxylate aminotransferase
AHNAK AHNAK nucleoprotein
AHNAK2 AHNAK nucleoprotein 2
AKIRIN1 akirin 1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ANGPTL5 angiopoietin-like 5
APLP1 amyloid beta (A4) precursor-like protein 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1
BBIP1 BBSome interacting protein 1
BBX bobby sox homolog (Drosophila)
BCAS1 breast carcinoma amplified sequence 1
BEST3 bestrophin 3
BMPR1B bone morphogenetic protein receptor, type IB
C2CD2 C2 calcium-dependent domain containing 2
CAPRIN1 cell cycle associated protein 1
CCDC148 coiled-coil domain containing 148
CD6 CD6 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CERS3 ceramide synthase 3
CHRM1 cholinergic receptor, muscarinic 1
CLEC4E C-type lectin domain family 4, member E
CLSTN3 calsyntenin 3
CMYA5 cardiomyopathy associated 5
COL19A1 collagen, type XIX, alpha 1
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
DCAF11 DDB1 and CUL4 associated factor 11
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAAF1 dynein, axonemal, assembly factor 1
DNAH11 dynein, axonemal, heavy chain 11
DNAH2 dynein, axonemal, heavy chain 2
DNAH9 dynein, axonemal, heavy chain 9
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOK3 docking protein 3
DPP3 dipeptidyl-peptidase 3
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1
E4F1 E4F transcription factor 1
EIF4A2 eukaryotic translation initiation factor 4A2
EML6 echinoderm microtubule associated protein like 6
ERVFRD-1 endogenous retrovirus group FRD, member 1
ESRRA estrogen-related receptor alpha
EVC2 Ellis van Creveld syndrome 2
EXOC4 exocyst complex component 4
FAM151A family with sequence similarity 151, member A
FAM35BP family with sequence similarity 35, member A pseudogene
FAM69B family with sequence similarity 69, member B
FASN fatty acid synthase
FAT3 FAT atypical cadherin 3
FAT4 FAT atypical cadherin 4
FCGBP Fc fragment of IgG binding protein
FGA fibrinogen alpha chain
FGD3 FYVE, RhoGEF and PH domain containing 3
FGFRL1 fibroblast growth factor receptor-like 1
FICD FIC domain containing
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FRAS1 Fraser extracellular matrix complex subunit 1
FREM1 FRAS1 related extracellular matrix 1
GAB3 GRB2-associated binding protein 3
GABPB2 GA binding protein transcription factor, beta subunit 2
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GH2 growth hormone 2
GPBP1 GC-rich promoter binding protein 1
GPER1 G protein-coupled estrogen receptor 1
GRAMD4 GRAM domain containing 4
GRHPR glyoxylate reductase/hydroxypyruvate reductase
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDAC11 histone deacetylase 11
HELZ helicase with zinc finger
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMCN1 hemicentin 1
HYDIN HYDIN, axonemal central pair apparatus protein
ICAM3 intercellular adhesion molecule 3
IPO5 importin 5
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCTD21 potassium channel tetramerization domain containing 21
KCTD7 potassium channel tetramerization domain containing 7
KHNYN KH and NYN domain containing
KIAA0825 KIAA0825
KIF1B kinesin family member 1B
KLK7 kallikrein-related peptidase 7
KMT2A lysine (K)-specific methyltransferase 2A
KRTAP10-9 keratin associated protein 10-9
KRTAP11-1 keratin associated protein 11-1
LCE3A late cornified envelope 3A
LIPI lipase, member I
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP1B low density lipoprotein receptor-related protein 1B
LRP2 low density lipoprotein receptor-related protein 2
LZTR1 leucine-zipper-like transcription regulator 1
MALT1 MALT1 paracaspase
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAPK9 mitogen-activated protein kinase 9
MEGF10 multiple EGF-like-domains 10
MORN1 MORN repeat containing 1
MTO1 mitochondrial tRNA translation optimization 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH15 myosin, heavy chain 15
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYH4 myosin, heavy chain 4, skeletal muscle
MYO10 myosin X
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative)
NBEAL2 neurobeachin-like 2
NCOR1 nuclear receptor corepressor 1
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NFRKB nuclear factor related to kappaB binding protein
NFYA nuclear transcription factor Y, alpha
NLRP14 NLR family, pyrin domain containing 14
NOTCH2NL notch 2 N-terminal like
NRXN3 neurexin 3
NUAK1 NUAK family, SNF1-like kinase, 1
NUP153 nucleoporin 153kDa
OR4C3 olfactory receptor, family 4, subfamily C, member 3
OR4K17 olfactory receptor, family 4, subfamily K, member 17
OR5AK2 olfactory receptor, family 5, subfamily AK, member 2
PALMD palmdelphin
PARP12 poly (ADP-ribose) polymerase family, member 12
PCSK5 proprotein convertase subtilisin/kexin type 5
PDCL3 phosducin-like 3
PDZRN4 PDZ domain containing ring finger 4
PGM1 phosphoglucomutase 1
PIAS2 protein inhibitor of activated STAT, 2
PITPNM3 PITPNM family member 3
POLN polymerase (DNA directed) nu
PPAPDC1A phosphatidic acid phosphatase type 2 domain containing 1A
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRAMEF1 PRAME family member 1
PRDM10 PR domain containing 10
PROP1 PROP paired-like homeobox 1
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
PRRC2C proline-rich coiled-coil 2C
PSORS1C1 psoriasis susceptibility 1 candidate 1
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RANBP2 RAN binding protein 2
RASA3 RAS p21 protein activator 3
RBL1 retinoblastoma-like 1
RFX6 regulatory factor X, 6
RHOBTB2 Rho-related BTB domain containing 2
RNASE8 ribonuclease, RNase A family, 8
RNF123 ring finger protein 123
RPS26P3 ribosomal protein S26 pseudogene 3
RPUSD3 RNA pseudouridylate synthase domain containing 3
RTTN rotatin
SAFB2 scaffold attachment factor B2
SALL1 spalt-like transcription factor 1
SCN7A sodium channel, voltage gated, type VII alpha subunit
SCNM1 sodium channel modifier 1
SCNN1D sodium channel, non voltage gated 1 delta subunit
SELPLG selectin P ligand
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SF3A1 splicing factor 3a, subunit 1, 120kDa
SFSWAP splicing factor, suppressor of white-apricot family
SGK494 uncharacterized serine/threonine-protein kinase SgK494
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SLC26A8 solute carrier family 26 (anion exchanger), member 8
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLIT3 slit homolog 3 (Drosophila)
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG5 SMG5 nonsense mediated mRNA decay factor
SMOC2 SPARC related modular calcium binding 2
SMTN smoothelin
SON SON DNA binding protein
SPEN spen family transcriptional repressor
STARD13 StAR-related lipid transfer (START) domain containing 13
STEAP3 STEAP family member 3, metalloreductase
STK11 serine/threonine kinase 11
STRBP spermatid perinuclear RNA binding protein
SUGP2 SURP and G patch domain containing 2
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYNE3 spectrin repeat containing, nuclear envelope family member 3
TCF4 transcription factor 4
TEKT5 tektin 5
TIAM2 T-cell lymphoma invasion and metastasis 2
TNC tenascin C
TNIP3 TNFAIP3 interacting protein 3
TNK2 tyrosine kinase, non-receptor, 2
TNRC6B trinucleotide repeat containing 6B
TRPC7 transient receptor potential cation channel, subfamily C, member 7
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSHZ1 teashirt zinc finger homeobox 1
TSHZ3 teashirt zinc finger homeobox 3
TSSK2 testis-specific serine kinase 2
TTN titin
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
UBN1 ubinuclein 1
UQCRC2 ubiquinol-cytochrome c reductase core protein II
USP29 ubiquitin specific peptidase 29
USP48 ubiquitin specific peptidase 48
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFY zinc finger protein, Y-linked
ZNF205 zinc finger protein 205
ZNF77 zinc finger protein 77
ZNF799 zinc finger protein 799