Pulmonary Embolism Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An artery disease characterized by a blockage of the main artery of the lung or one of its branches by a substance that has travelled from elsewhere in the body, e.g. a blood clot. (Human Disease Ontology, DOID_9477)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D011655
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Genes

669 genes/proteins associated with the disease Pulmonary Embolism from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CAT catalase 2.88009
TBXA2R thromboxane A2 receptor 2.88009
FGA fibrinogen alpha chain 2.88009
DAB2IP DAB2 interacting protein 2.88009
THBD thrombomodulin 2.88009
MERTK MER proto-oncogene, tyrosine kinase 2.88009
XDH xanthine dehydrogenase 2.88009
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 2.88009
PLAU plasminogen activator, urokinase 2.88009
PLAT plasminogen activator, tissue 2.88009
TNF tumor necrosis factor 2.34564
MAPK3 mitogen-activated protein kinase 3 2.22537
MAPK1 mitogen-activated protein kinase 1 2.1882
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.18447
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.13058
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.06343
TP53 tumor protein p53 2.04202
VEGFA vascular endothelial growth factor A 2.03599
FOS FBJ murine osteosarcoma viral oncogene homolog 2.01897
IL6 interleukin 6 1.95812
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.94124
JUN jun proto-oncogene 1.93751
SOD1 superoxide dismutase 1, soluble 1.9296
BCL2 B-cell CLL/lymphoma 2 1.92753
PRL prolactin 1.91732
CCL2 chemokine (C-C motif) ligand 2 1.91418
FAS Fas cell surface death receptor 1.91334
MAPK8 mitogen-activated protein kinase 8 1.90935
IL1B interleukin 1, beta 1.90275
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.88995
BAX BCL2-associated X protein 1.88491
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.87742
TGFB1 transforming growth factor, beta 1 1.86184
IFNG interferon, gamma 1.8393
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.83646
NOS2 nitric oxide synthase 2, inducible 1.83254
FGF2 fibroblast growth factor 2 (basic) 1.83219
F2 coagulation factor II (thrombin) 1.81611
SOD2 superoxide dismutase 2, mitochondrial 1.81574
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.7977
EGR1 early growth response 1 1.78797
MCL1 myeloid cell leukemia 1 1.75162
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.74943
CYCS cytochrome c, somatic 1.73434
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.73008
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.72405
F2R coagulation factor II (thrombin) receptor 1.70823
TAGLN transgelin 1.70574
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.70077
MPO myeloperoxidase 1.69426
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.6906
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.6857
FASLG Fas ligand (TNF superfamily, member 6) 1.67526
VCAM1 vascular cell adhesion molecule 1 1.67441
RB1 retinoblastoma 1 1.66921
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.66921
NOS3 nitric oxide synthase 3 (endothelial cell) 1.66641
THBS1 thrombospondin 1 1.65775
ADCY7 adenylate cyclase 7 1.65621
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.65204
NPPB natriuretic peptide B 1.64685
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.64528
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.64056
SPP1 secreted phosphoprotein 1 1.63698
CCND3 cyclin D3 1.63428
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.62893
CCND1 cyclin D1 1.6278
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.62445
FSHB follicle stimulating hormone, beta polypeptide 1.61851
PARP1 poly (ADP-ribose) polymerase 1 1.61575
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.61248
HMOX1 heme oxygenase 1 1.60897
F3 coagulation factor III (thromboplastin, tissue factor) 1.60827
ATF3 activating transcription factor 3 1.60454
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.6043
MAPK14 mitogen-activated protein kinase 14 1.60314
BAD BCL2-associated agonist of cell death 1.60105
CCNB1 cyclin B1 1.59989
IL10 interleukin 10 1.59591
C3 complement component 3 1.59101
IGFBP4 insulin-like growth factor binding protein 4 1.59077
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.57712
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.56994
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.56923
GSK3B glycogen synthase kinase 3 beta 1.56337
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.5619
LHB luteinizing hormone beta polypeptide 1.55231
MMP9 matrix metallopeptidase 9 1.5501
MUC1 mucin 1, cell surface associated 1.54912
ALB albumin 1.5462
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.53724
IGF1 insulin-like growth factor 1 (somatomedin C) 1.53675
FHL1 four and a half LIM domains 1 1.53456
BCL2L1 BCL2-like 1 1.52963
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.52767
MKI67 marker of proliferation Ki-67 1.52338
HSPA8 heat shock 70kDa protein 8 1.52011
GSTP1 glutathione S-transferase pi 1 1.51784
NUPR1 nuclear protein, transcriptional regulator, 1 1.51506
SGK1 serum/glucocorticoid regulated kinase 1 1.51506
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.5108
EGFR epidermal growth factor receptor 1.51004
G6PD glucose-6-phosphate dehydrogenase 1.50903
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.50751
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1.5065
LCN2 lipocalin 2 1.50348
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.50348
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.50323
BDNF brain-derived neurotrophic factor 1.50298
EMP3 epithelial membrane protein 3 1.50223
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.49736
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.49407
SREBF1 sterol regulatory element binding transcription factor 1 1.49071
PCNA proliferating cell nuclear antigen 1.48941
LY6E lymphocyte antigen 6 complex, locus E 1.48838
CALR calreticulin 1.47374
CDK4 cyclin-dependent kinase 4 1.47012
IL2 interleukin 2 1.46883
CXCL8 chemokine (C-X-C motif) ligand 8 1.46781
EPO erythropoietin 1.46015
REN renin 1.45962
BIRC5 baculoviral IAP repeat containing 5 1.45777
RGS10 regulator of G-protein signaling 10 1.44735
PSAP prosaposin 1.44626
VLDLR very low density lipoprotein receptor 1.4449
CCNA2 cyclin A2 1.44327
TNC tenascin C 1.44193
THY1 Thy-1 cell surface antigen 1.43048
CDK2 cyclin-dependent kinase 2 1.42967
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.42804
G0S2 G0/G1 switch 2 1.42535
MMP2 matrix metallopeptidase 2 1.42374
IL4 interleukin 4 1.42374
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.42183
MGP matrix Gla protein 1.41992
NAMPT nicotinamide phosphoribosyltransferase 1.41478
TOP2A topoisomerase (DNA) II alpha 170kDa 1.41313
CCL11 chemokine (C-C motif) ligand 11 1.40705
ZEB1 zinc finger E-box binding homeobox 1 1.40486
ERBB2 erb-b2 receptor tyrosine kinase 2 1.40373
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.39785
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.39757
FSCN1 fascin actin-bundling protein 1 1.39757
CTSL cathepsin L 1.3917
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.38355
DES desmin 1.37761
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.37446
COL1A2 collagen, type I, alpha 2 1.3736
CYP3A cytochrome P450, family 3, subfamily A 1.37103
PALLD palladin, cytoskeletal associated protein 1.36848
STAT2 signal transducer and activator of transcription 2, 113kDa 1.36848
CAPN2 calpain 2, (m/II) large subunit 1.36476
POR P450 (cytochrome) oxidoreductase 1.36332
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.36304
CXCL10 chemokine (C-X-C motif) ligand 10 1.3619
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.35906
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.35849
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.35849
LDHA lactate dehydrogenase A 1.35849
ACTA2 actin, alpha 2, smooth muscle, aorta 1.35502
GADD45A growth arrest and DNA-damage-inducible, alpha 1.35415
STMN1 stathmin 1 1.35386
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.35357
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.34926
IGFBP3 insulin-like growth factor binding protein 3 1.34694
CCL3 chemokine (C-C motif) ligand 3 1.34664
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.34635
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.34518
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.34372
SATB1 SATB homeobox 1 1.34314
COMT catechol-O-methyltransferase 1.34198
BIRC3 baculoviral IAP repeat containing 3 1.34198
ICAM1 intercellular adhesion molecule 1 1.34111
C10ORF10 chromosome 10 open reading frame 10 1.33346
LMCD1 LIM and cysteine-rich domains 1 1.33346
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.33346
COL1A1 collagen, type I, alpha 1 1.33257
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.33199
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 1.33169
TCP1 t-complex 1 1.32935
TPI1 triosephosphate isomerase 1 1.32876
RRM2 ribonucleotide reductase M2 1.32756
CYR61 cysteine-rich, angiogenic inducer, 61 1.32756
SRXN1 sulfiredoxin 1 1.32547
CRP C-reactive protein, pentraxin-related 1.32518
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.31716
MMP1 matrix metallopeptidase 1 1.31716
ADAM17 ADAM metallopeptidase domain 17 1.31716
C1QA complement component 1, q subcomponent, A chain 1.31716
GPX3 glutathione peroxidase 3 1.31506
ZFP36L1 ZFP36 ring finger protein-like 1 1.30941
NCOA1 nuclear receptor coactivator 1 1.30911
IL5 interleukin 5 1.30911
MAOA monoamine oxidase A 1.30911
FOXO1 forkhead box O1 1.30635
TSC22D3 TSC22 domain family, member 3 1.30635
CREB1 cAMP responsive element binding protein 1 1.30543
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 1.30543
ALDOA aldolase A, fructose-bisphosphate 1.3036
PGR progesterone receptor 1.30147
STAT1 signal transducer and activator of transcription 1, 91kDa 1.30117
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.29843
COL6A3 collagen, type VI, alpha 3 1.29781
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.29781
CLU clusterin 1.29781
NRP1 neuropilin 1 1.29564
UBE2C ubiquitin-conjugating enzyme E2C 1.29564
CCND2 cyclin D2 1.29471
ATF5 activating transcription factor 5 1.29379
IL1A interleukin 1, alpha 1.29041
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 1.28796
EEF2 eukaryotic translation elongation factor 2 1.28796
MAPT microtubule-associated protein tau 1.28703
BTG2 BTG family, member 2 1.28703
SP1 Sp1 transcription factor 1.28703
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.28395
ALCAM activated leukocyte cell adhesion molecule 1.28303
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.28303
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.28272
OXT oxytocin/neurophysin I prepropeptide 1.28027
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.28027
CAV1 caveolin 1, caveolae protein, 22kDa 1.27936
EDN1 endothelin 1 1.27936
ODC1 ornithine decarboxylase 1 1.27813
CD40LG CD40 ligand 1.27255
OAT ornithine aminotransferase 1.27255
IRF7 interferon regulatory factor 7 1.27224
ALOX5AP arachidonate 5-lipoxygenase-activating protein 1.26886
PROS1 protein S (alpha) 1.26886
FOSL1 FOS-like antigen 1 1.26638
HPCAL1 hippocalcin-like 1 1.26638
VGF VGF nerve growth factor inducible 1.26638
TYMP thymidine phosphorylase 1.26545
AVP arginine vasopressin 1.26545
EGR2 early growth response 2 1.26298
CTSK cathepsin K 1.26205
ACP5 acid phosphatase 5, tartrate resistant 1.26205
GATA4 GATA binding protein 4 1.26205
DDIT3 DNA-damage-inducible transcript 3 1.26144
IGFBP5 insulin-like growth factor binding protein 5 1.26052
GLRX glutaredoxin (thioltransferase) 1.25899
PDGFA platelet-derived growth factor alpha polypeptide 1.25807
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.25557
MYB v-myb avian myeloblastosis viral oncogene homolog 1.25557
CD86 CD86 molecule 1.25557
CFB complement factor B 1.24591
FAM65B family with sequence similarity 65, member B 1.2456
TYMS thymidylate synthetase 1.24496
PDGFB platelet-derived growth factor beta polypeptide 1.24433
EGF epidermal growth factor 1.24401
EMP1 epithelial membrane protein 1 1.24275
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 1.24275
HSPH1 heat shock 105kDa/110kDa protein 1 1.24213
HPN hepsin 1.24181
NPY1R neuropeptide Y receptor Y1 1.24181
RGS2 regulator of G-protein signaling 2 1.23962
CDK5 cyclin-dependent kinase 5 1.23712
TAT tyrosine aminotransferase 1.23648
NFE2L2 nuclear factor, erythroid 2-like 2 1.23552
PENK proenkephalin 1.2352
ERBB3 erb-b2 receptor tyrosine kinase 3 1.23328
RBPMS RNA binding protein with multiple splicing 1.23233
CDC20 cell division cycle 20 1.23074
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.23042
GPNMB glycoprotein (transmembrane) nmb 1.23011
PLG plasminogen 1.23011
LDLR low density lipoprotein receptor 1.2279
KRT18 keratin 18, type I 1.22632
COL4A1 collagen, type IV, alpha 1 1.22404
IL12B interleukin 12B 1.22371
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.22339
CD8A CD8a molecule 1.22339
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.22242
BUB3 BUB3 mitotic checkpoint protein 1.22242
INHBE inhibin, beta E 1.22112
NCOA2 nuclear receptor coactivator 2 1.21823
CCL21 chemokine (C-C motif) ligand 21 1.21791
BIRC2 baculoviral IAP repeat containing 2 1.21567
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 1.21567
CSF1 colony stimulating factor 1 (macrophage) 1.21534
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.21534
TUBB2B tubulin, beta 2B class IIb 1.21435
TPD52 tumor protein D52 1.21435
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.21435
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 1.21435
RAB31 RAB31, member RAS oncogene family 1.21435
MAP2K1 mitogen-activated protein kinase kinase 1 1.21304
LTF lactotransferrin 1.21206
CD38 CD38 molecule 1.21206
CRH corticotropin releasing hormone 1.21141
APP amyloid beta (A4) precursor protein 1.21011
OLFML3 olfactomedin-like 3 1.21011
DYNLL1 dynein, light chain, LC8-type 1 1.21011
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.21011
DCN decorin 1.20913
WAS Wiskott-Aldrich syndrome 1.20784
KRT8 keratin 8, type II 1.20719
CSF3 colony stimulating factor 3 (granulocyte) 1.20719
CTGF connective tissue growth factor 1.20654
MDK midkine (neurite growth-promoting factor 2) 1.2059
ESR1 estrogen receptor 1 1.2059
CTSH cathepsin H 1.2059
PA2G4 proliferation-associated 2G4, 38kDa 1.2059
UBXN4 UBX domain protein 4 1.20361
CD36 CD36 molecule (thrombospondin receptor) 1.20163
ACKR3 atypical chemokine receptor 3 1.20163
NQO1 NAD(P)H dehydrogenase, quinone 1 1.20097
FADD Fas (TNFRSF6)-associated via death domain 1.20064
PPARG peroxisome proliferator-activated receptor gamma 1.20031
GPX1 glutathione peroxidase 1 1.199
H2AFX H2A histone family, member X 1.19835
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 1.19737
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.19672
CDK1 cyclin-dependent kinase 1 1.19639
CCL5 chemokine (C-C motif) ligand 5 1.19509
CCNG2 cyclin G2 1.19509
UNG uracil-DNA glycosylase 1.19509
RFTN1 raftlin, lipid raft linker 1 1.19379
APOE apolipoprotein E 1.19379
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 1.19312
GJA1 gap junction protein, alpha 1, 43kDa 1.1908
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.19047
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 1.19047
AR androgen receptor 1.18981
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.18948
VIM vimentin 1.18751
CD3G CD3g molecule, gamma (CD3-TCR complex) 1.18718
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.18521
CSK c-src tyrosine kinase 1.18521
SMAD2 SMAD family member 2 1.18424
CKB creatine kinase, brain 1.18424
HDAC1 histone deacetylase 1 1.18424
KLF4 Kruppel-like factor 4 (gut) 1.18159
TFRC transferrin receptor 1.18159
GSN gelsolin 1.18159
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.18159
HMGB2 high mobility group box 2 1.18126
FAM134B family with sequence similarity 134, member B 1.18093
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.18059
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.1786
FAM19A5 family with sequence similarity 19 (chemokine (C-C motif)-like), member A5 1.17827
LCK LCK proto-oncogene, Src family tyrosine kinase 1.17728
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.17728
ADD3 adducin 3 (gamma) 1.17728
E2F1 E2F transcription factor 1 1.17497
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 1.17464
BPTF bromodomain PHD finger transcription factor 1.17464
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.17399
GAMT guanidinoacetate N-methyltransferase 1.17366
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 1.17333
TRIB3 tribbles pseudokinase 3 1.173
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.17101
CTSB cathepsin B 1.17101
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.17101
KRT17 keratin 17, type I 1.16967
TIMP1 TIMP metallopeptidase inhibitor 1 1.16967
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 1.16967
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 1.16833
MCM2 minichromosome maintenance complex component 2 1.16833
ATF4 activating transcription factor 4 1.16733
DUSP1 dual specificity phosphatase 1 1.16666
RUNX1 runt-related transcription factor 1 1.166
MAP2K3 mitogen-activated protein kinase kinase 3 1.166
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.166
RELN reelin 1.166
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.16567
LMNA lamin A/C 1.16567
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.16533
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.16236
RPA3 replication protein A3, 14kDa 1.16236
RHOBTB3 Rho-related BTB domain containing 3 1.16236
HSPE1 heat shock 10kDa protein 1 1.1607
BCAT1 branched chain amino-acid transaminase 1, cytosolic 1.15865
S100A11 S100 calcium binding protein A11 1.15865
FASN fatty acid synthase 1.15661
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.15627
DDIT4 DNA-damage-inducible transcript 4 1.15593
INHBA inhibin, beta A 1.1556
LPL lipoprotein lipase 1.15526
MMP3 matrix metallopeptidase 3 1.15256
DBP D site of albumin promoter (albumin D-box) binding protein 1.15122
FAM107A family with sequence similarity 107, member A 1.15055
FKBP5 FK506 binding protein 5 1.14816
FHL2 four and a half LIM domains 2 1.14781
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.14781
LEF1 lymphoid enhancer-binding factor 1 1.14781
TRAF5 TNF receptor-associated factor 5 1.14507
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.14507
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 1.14473
WNT5A wingless-type MMTV integration site family, member 5A 1.14404
LAMC2 laminin, gamma 2 1.14404
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.14404
BMP4 bone morphogenetic protein 4 1.14336
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.14336
CXCL12 chemokine (C-X-C motif) ligand 12 1.14336
CCNE1 cyclin E1 1.14234
C1QB complement component 1, q subcomponent, B chain 1.14064
CP ceruloplasmin (ferroxidase) 1.13997
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.13963
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 1.13929
FLOT1 flotillin 1 1.13929
AKAP12 A kinase (PRKA) anchor protein 12 1.13724
SDC1 syndecan 1 1.13724
RORA RAR-related orphan receptor A 1.13724
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.13518
STX16 syntaxin 16 1.13415
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.13381
TJP1 tight junction protein 1 1.13381
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.13381
CCL7 chemokine (C-C motif) ligand 7 1.13381
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.13381
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.13381
S100A9 S100 calcium binding protein A9 1.13143
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.13143
NREP neuronal regeneration related protein 1.13041
RBP4 retinol binding protein 4, plasma 1.12737
ISG15 ISG15 ubiquitin-like modifier 1.12737
IGFBP6 insulin-like growth factor binding protein 6 1.12737
GSR glutathione reductase 1.12668
PHC2 polyhomeotic homolog 2 (Drosophila) 1.12461
COL18A1 collagen, type XVIII, alpha 1 1.12391
FBN1 fibrillin 1 1.12391
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 1.12357
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 1.12357
CSE1L CSE1 chromosome segregation 1-like (yeast) 1.12323
HBEGF heparin-binding EGF-like growth factor 1.12219
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.12219
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.12219
RGS4 regulator of G-protein signaling 4 1.12082
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 1.12082
EI24 etoposide induced 2.4 1.11843
TYROBP TYRO protein tyrosine kinase binding protein 1.11843
CST3 cystatin C 1.11741
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.11741
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.11571
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.11571
GSTM1 glutathione S-transferase mu 1 1.11466
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.11431
EVI2A ecotropic viral integration site 2A 1.11325
NFE2L1 nuclear factor, erythroid 2-like 1 1.11325
ABHD2 abhydrolase domain containing 2 1.11325
UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.11325
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.1129
FN1 fibronectin 1 1.1129
PDIA4 protein disulfide isomerase family A, member 4 1.11116
UGCG UDP-glucose ceramide glucosyltransferase 1.11116
PRKCB protein kinase C, beta 1.10907
MAOB monoamine oxidase B 1.10907
EMP2 epithelial membrane protein 2 1.10838
SKAP2 src kinase associated phosphoprotein 2 1.10838
BCL6 B-cell CLL/lymphoma 6 1.10803
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.10665
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.10596
IL15RA interleukin 15 receptor, alpha 1.10596
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.10493
CA12 carbonic anhydrase XII 1.10353
CD4 CD4 molecule 1.10353
GCLC glutamate-cysteine ligase, catalytic subunit 1.10317
ANXA2 annexin A2 1.10246
BBC3 BCL2 binding component 3 1.10246
ADM adrenomedullin 1.10033
ABHD4 abhydrolase domain containing 4 1.09857
MXI1 MAX interactor 1, dimerization protein 1.09857
PPIB peptidylprolyl isomerase B (cyclophilin B) 1.09857
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.09857
ACSS2 acyl-CoA synthetase short-chain family member 2 1.09857
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.09822
CHUK conserved helix-loop-helix ubiquitous kinase 1.09611
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.09576
TMPO thymopoietin 1.09576
CD68 CD68 molecule 1.09576
ERBB4 erb-b2 receptor tyrosine kinase 4 1.09401
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 1.09401
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 1.09366
GAS6 growth arrest-specific 6 1.09262
INS insulin 1.09262
FOSL2 FOS-like antigen 2 1.09262
CDC25A cell division cycle 25A 1.09262
FABP1 fatty acid binding protein 1, liver 1.0919
CCNG1 cyclin G1 1.0919
CDKN2A cyclin-dependent kinase inhibitor 2A 1.09154
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.08975
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.08975
MAP2K2 mitogen-activated protein kinase kinase 2 1.08975
DUSP2 dual specificity phosphatase 2 1.0894
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 1.0894
UBL3 ubiquitin-like 3 1.08904
ANKRD28 ankyrin repeat domain 28 1.08904
IFI30 interferon, gamma-inducible protein 30 1.08904
MOK MOK protein kinase 1.08868
RBMS3 RNA binding motif, single stranded interacting protein 3 1.08868
ACSL1 acyl-CoA synthetase long-chain family member 1 1.08762
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.08655
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.08655
GATA3 GATA binding protein 3 1.08655
IER3 immediate early response 3 1.08549
CFLAR CASP8 and FADD-like apoptosis regulator 1.08549
DLAT dihydrolipoamide S-acetyltransferase 1.08478
KAT2B K(lysine) acetyltransferase 2B 1.08478
STOM stomatin 1.08478
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.08372
SIGMAR1 sigma non-opioid intracellular receptor 1 1.08372
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.08337
IRS1 insulin receptor substrate 1 1.08337
PON1 paraoxonase 1 1.08196
APOA1 apolipoprotein A-I 1.08196
TXNIP thioredoxin interacting protein 1.08126
JAG1 jagged 1 1.08091
GRN granulin 1.08091
NUSAP1 nucleolar and spindle associated protein 1 1.08091
PHGDH phosphoglycerate dehydrogenase 1.08091
P4HB prolyl 4-hydroxylase, beta polypeptide 1.08091
FGFR3 fibroblast growth factor receptor 3 1.08091
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 1.08091
HMHA1 histocompatibility (minor) HA-1 1.08055
LSP1 lymphocyte-specific protein 1 1.08019
SRGN serglycin 1.08019
TRIM2 tripartite motif containing 2 1.08019
CCNB2 cyclin B2 1.07947
CXCR6 chemokine (C-X-C motif) receptor 6 1.07947
MARCKS myristoylated alanine-rich protein kinase C substrate 1.07804
CDC42 cell division cycle 42 1.07804
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.07804
MGST1 microsomal glutathione S-transferase 1 1.07732
RAMP2 receptor (G protein-coupled) activity modifying protein 2 1.07589
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 1.07553
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 1.07553
MAP2K6 mitogen-activated protein kinase kinase 6 1.07518
PDK1 pyruvate dehydrogenase kinase, isozyme 1 1.07518
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 1.07305
SLCO4C1 solute carrier organic anion transporter family, member 4C1 1.07269
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.07234
KMT2A lysine (K)-specific methyltransferase 2A 1.07163
PPP1R10 protein phosphatase 1, regulatory subunit 10 1.07163
NPPA natriuretic peptide A 1.07128
EDNRB endothelin receptor type B 1.07128
INSIG1 insulin induced gene 1 1.07128
F8 coagulation factor VIII, procoagulant component 1.07128
HPSE heparanase 1.07128
IL1RN interleukin 1 receptor antagonist 1.07128
HSPA1B heat shock 70kDa protein 1B 1.06952
FABP3 fatty acid binding protein 3, muscle and heart 1.06952
PTGES prostaglandin E synthase 1.06952
FST follistatin 1.06952
TGFB2 transforming growth factor, beta 2 1.06917
BAK1 BCL2-antagonist/killer 1 1.06734
IRF9 interferon regulatory factor 9 1.06698
ACO2 aconitase 2, mitochondrial 1.06698
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.06698
PDLIM7 PDZ and LIM domain 7 (enigma) 1.06698
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.06698
NPTN neuroplastin 1.06552
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.06552
LAMA3 laminin, alpha 3 1.06297
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 1.06261
MUCL1 mucin-like 1 1.06225
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.06116
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 1.06116
E2F2 E2F transcription factor 2 1.059
CXCL5 chemokine (C-X-C motif) ligand 5 1.05864
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.05864
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.05864
IFITM1 interferon induced transmembrane protein 1 1.05864
PLK1 polo-like kinase 1 1.05864
ASPH aspartate beta-hydroxylase 1.05864
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 1.05864
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 1.05793
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.05573
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.05573
KLF9 Kruppel-like factor 9 1.05573
GHR growth hormone receptor 1.05573
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.05461
IGFBP7 insulin-like growth factor binding protein 7 1.05423
ADIPOQ adiponectin, C1Q and collagen domain containing 1.05349
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.05163
SKI SKI proto-oncogene 1.05052
EPAS1 endothelial PAS domain protein 1 1.05052
BTG3 BTG family, member 3 1.05052
S100A6 S100 calcium binding protein A6 1.05052
TRAF2 TNF receptor-associated factor 2 1.05052
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.05015
PDE4B phosphodiesterase 4B, cAMP-specific 1.04757
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.04757
LAMP2 lysosomal-associated membrane protein 2 1.04611
NR2F1 nuclear receptor subfamily 2, group F, member 1 1.04611
TOB1 transducer of ERBB2, 1 1.04611
BTG1 B-cell translocation gene 1, anti-proliferative 1.04501
BHLHE40 basic helix-loop-helix family, member e40 1.04501
MGMT O-6-methylguanine-DNA methyltransferase 1.04427
LAT linker for activation of T cells 1.04352
TRIM25 tripartite motif containing 25 1.04314
LUM lumican 1.04201
NINJ1 ninjurin 1 1.04201
FBLN1 fibulin 1 1.04201
SRM spermidine synthase 1.04201
ACTB actin, beta 1.04014
HSPA4 heat shock 70kDa protein 4 1.03976
ATF2 activating transcription factor 2 1.03976
HSPA1A heat shock 70kDa protein 1A 1.03901
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.03901
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.03864
CALB1 calbindin 1, 28kDa 1.03827
SFRP2 secreted frizzled-related protein 2 1.03789
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.03715
RAD17 RAD17 homolog (S. pombe) 1.03641
PRKCSH protein kinase C substrate 80K-H 1.03641
HSPB3 heat shock 27kDa protein 3 1.03641
NUDC nudC nuclear distribution protein 1.03641
COPE coatomer protein complex, subunit epsilon 1.03641
GFI1 growth factor independent 1 transcription repressor 1.03641
CD14 CD14 molecule 1.03456
PRKG1 protein kinase, cGMP-dependent, type I 1.03456
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 1.03456
NCOA3 nuclear receptor coactivator 3 1.03419
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 1.03419
MSMO1 methylsterol monooxygenase 1 1.03197
IGF1R insulin-like growth factor 1 receptor 1.03122
CAMK2B calcium/calmodulin-dependent protein kinase II beta 1.03046
PTPRC protein tyrosine phosphatase, receptor type, C 1.03046
FMO5 flavin containing monooxygenase 5 1.03046
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 1.03046
FMOD fibromodulin 1.03046
FDPS farnesyl diphosphate synthase 1.02971
MCM6 minichromosome maintenance complex component 6 1.02933
UBE2J1 ubiquitin-conjugating enzyme E2, J1 1.02933
AURKA aurora kinase A 1.02708
AVPR1A arginine vasopressin receptor 1A 1.02708
GEM GTP binding protein overexpressed in skeletal muscle 1.02671
S100P S100 calcium binding protein P 1.02671
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 1.02671
TMSB10 thymosin beta 10 1.02634
CTSD cathepsin D 1.02559
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.02447
FNDC4 fibronectin type III domain containing 4 1.02373
SQSTM1 sequestosome 1 1.02373
MR1 major histocompatibility complex, class I-related 1.02336
LMO4 LIM domain only 4 1.02299
TFPI2 tissue factor pathway inhibitor 2 1.02299
BID BH3 interacting domain death agonist 1.02225
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.02188
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.0204
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.0204
MBP myelin basic protein 1.01966
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.01966
MAPK9 mitogen-activated protein kinase 9 1.01966
RHOB ras homolog family member B 1.01966
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.01928
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 1.01928
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 1.01928
PTMA prothymosin, alpha 1.01928
NAP1L1 nucleosome assembly protein 1-like 1 1.01928
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.01852
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.01701
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 1.01701
PCCB propionyl CoA carboxylase, beta polypeptide 1.01701
PRLR prolactin receptor 1.01701
ITGB7 integrin, beta 7 1.01663
HELB helicase (DNA) B 1.01587
BCL3 B-cell CLL/lymphoma 3 1.01549
AQP1 aquaporin 1 (Colton blood group) 1.01474
ALAS1 5'-aminolevulinate synthase 1 1.01474
AQP3 aquaporin 3 (Gill blood group) 1.01249
KLK3 kallikrein-related peptidase 3 1.01249
APOD apolipoprotein D 1.01212
STK38 serine/threonine kinase 38 1.01099
RBM24 RNA binding motif protein 24 1.01062
MFN2 mitofusin 2 1.01062
SRI sorcin 1.01062
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.01025