Pulmonary Disease, Chronic Obstructive Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D029424
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Genes

89 genes/proteins associated with the disease Pulmonary Disease, Chronic Obstructive from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.88009
FAM13A family with sequence similarity 13, member A 2.88009
CD8A CD8a molecule 2.88009
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 2.88009
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.88009
NOS3 nitric oxide synthase 3 (endothelial cell) 2.88009
TNF tumor necrosis factor 2.88009
HDAC2 histone deacetylase 2 2.88009
NOS2 nitric oxide synthase 2, inducible 2.88009
MMP1 matrix metallopeptidase 1 2.88009
MMP14 matrix metallopeptidase 14 (membrane-inserted) 2.88009
SOD3 superoxide dismutase 3, extracellular 2.88009
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.88009
CXCL8 chemokine (C-X-C motif) ligand 8 2.88009
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 2.88009
TGFB1 transforming growth factor, beta 1 2.88009
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 2.88009
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 2.88009
MMP9 matrix metallopeptidase 9 2.88009
COPD Pulmonary disease, chronic obstructive, severe early-onset 2.88009
TNNT2 troponin T type 2 (cardiac) 2.88009
TP53 tumor protein p53 2.88009
HMOX1 heme oxygenase 1 2.88009
IL1B interleukin 1, beta 1.62335
IL6 interleukin 6 1.58279
IL13 interleukin 13 1.47838
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.45458
ADRB1 adrenoceptor beta 1 1.45273
THY1 Thy-1 cell surface antigen 1.39338
CCL3 chemokine (C-C motif) ligand 3 1.36876
MAPK1 mitogen-activated protein kinase 1 1.36476
CCL5 chemokine (C-C motif) ligand 5 1.32547
IL10 interleukin 10 1.3228
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.3103
SOD2 superoxide dismutase 2, mitochondrial 1.30543
MAPK3 mitogen-activated protein kinase 3 1.29564
CD44 CD44 molecule (Indian blood group) 1.26978
ACTA2 actin, alpha 2, smooth muscle, aorta 1.26483
VCAM1 vascular cell adhesion molecule 1 1.2639
CCL11 chemokine (C-C motif) ligand 11 1.26175
FN1 fibronectin 1 1.23899
CCL2 chemokine (C-C motif) ligand 2 1.23584
S100A9 S100 calcium binding protein A9 1.23488
ADRB2 adrenoceptor beta 2, surface 1.23392
EDN1 endothelin 1 1.21823
MPO myeloperoxidase 1.21173
NPPB natriuretic peptide B 1.19737
TLR4 toll-like receptor 4 1.19509
SPP1 secreted phosphoprotein 1 1.19213
CLU clusterin 1.18948
FGF2 fibroblast growth factor 2 (basic) 1.18816
IL4 interleukin 4 1.18359
BCL2 B-cell CLL/lymphoma 2 1.1786
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.17431
STAR steroidogenic acute regulatory protein 1.17034
PPARG peroxisome proliferator-activated receptor gamma 1.16666
F3 coagulation factor III (thromboplastin, tissue factor) 1.16203
CAT catalase 1.16137
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.1607
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 1.13963
AOC1 amine oxidase, copper containing 1 1.12838
IL1A interleukin 1, alpha 1.11843
BDKRB1 bradykinin receptor B1 1.11741
SFTPB surfactant protein B 1.1136
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.1136
ICAM1 intercellular adhesion molecule 1 1.10942
RNASE3 ribonuclease, RNase A family, 3 1.09646
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.08868
CTGF connective tissue growth factor 1.08091
IFNG interferon, gamma 1.0784
TIMP1 TIMP metallopeptidase inhibitor 1 1.07411
IL18 interleukin 18 1.07376
GPX2 glutathione peroxidase 2 1.07234
LBP lipopolysaccharide binding protein 1.07093
NPPA natriuretic peptide A 1.06406
SIRT2 sirtuin 2 1.05423
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.05237
FOS FBJ murine osteosarcoma viral oncogene homolog 1.052
DUSP1 dual specificity phosphatase 1 1.04501
GALNT4 polypeptide N-acetylgalactosaminyltransferase 4 1.04465
COL3A1 collagen, type III, alpha 1 1.04352
ADRB3 adrenoceptor beta 3 1.04239
RB1 retinoblastoma 1 1.03197
THBD thrombomodulin 1.03084
CXCL10 chemokine (C-X-C motif) ligand 10 1.02783
PER2 period circadian clock 2 1.02522
GSTM1 glutathione S-transferase mu 1 1.02447
VEGFA vascular endothelial growth factor A 1.02151
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.01249