Psoriasis Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description A skin abnormality characterized by redness and irritation, with thick, red skin that displays flaky, silver-white patches (scales). (Human Phenotype Ontology, HP_0003765)
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Genes

42 genes associated with the trait Psoriasis in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
PSORS1C1 psoriasis susceptibility 1 candidate 1 1.73051
C2 complement component 2 1.72563
TNXB tenascin XB 1.70626
HLA-C major histocompatibility complex, class I, C 1.67717
HCP5 HLA complex P5 (non-protein coding) 1.5935
IL12B interleukin 12B 1.58905
NOTCH4 notch 4 1.53379
ABHD16A abhydrolase domain containing 16A 1.52112
CCHCR1 coiled-coil alpha-helical rod protein 1 1.44482
TNF tumor necrosis factor 1.43587
GPSM3 G-protein signaling modulator 3 1.41234
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 1.39999
LST1 leukocyte specific transcript 1 1.36357
HLA-DOB major histocompatibility complex, class II, DO beta 1.35521
MUC21 mucin 21, cell surface associated 1.31316
AGER advanced glycosylation end product-specific receptor 1.31009
RNF5 ring finger protein 5, E3 ubiquitin protein ligase 1.31009
TRIM15 tripartite motif containing 15 1.30299
TRAF3IP2 TRAF3 interacting protein 2 1.27677
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.23717
IL13 interleukin 13 1.19362
PSORS1C2 psoriasis susceptibility 1 candidate 2 1.18862
TRIM40 tripartite motif containing 40 1.18134
C6ORF10 chromosome 6 open reading frame 10 1.16457
DDR1 discoidin domain receptor tyrosine kinase 1 1.13227
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7 1.12979
TCF19 transcription factor 19 1.09808
DPCR1 diffuse panbronchiolitis critical region 1 1.07782
MCCD1 mitochondrial coiled-coil domain 1 1.06308
PBX2 pre-B-cell leukemia homeobox 2 1.05411
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.01773
ERAP1 endoplasmic reticulum aminopeptidase 1 0.982475
CAST calpastatin 0.982475
TYK2 tyrosine kinase 2 0.973188
NOS2 nitric oxide synthase 2, inducible 0.973188
FBXL19 F-box and leucine-rich repeat protein 19 0.866561
STAT2 signal transducer and activator of transcription 2, 113kDa 0.862644
SPATA2 spermatogenesis associated 2 0.763999
KIAA0391 KIAA0391 0.731179
IL23R interleukin 23 receptor 0.711358
COG6 component of oligomeric golgi complex 6 0.443956
TSC1 tuberous sclerosis 1 0.33862