Psoriasis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A skin abnormality characterized by redness and irritation, with thick, red skin that displays flaky, silver-white patches (scales). (Human Phenotype Ontology, HP_0003765)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D011565
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Genes

120 genes/proteins associated with the disease Psoriasis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
HCAR2 hydroxycarboxylic acid receptor 2 2.88009
RNF114 ring finger protein 114 2.88009
S100A7 S100 calcium binding protein A7 2.88009
CRP C-reactive protein, pentraxin-related 2.88009
TRAF3IP2 TRAF3 interacting protein 2 2.88009
MKI67 marker of proliferation Ki-67 2.88009
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 2.88009
REN renin 2.88009
REL v-rel avian reticuloendotheliosis viral oncogene homolog 2.88009
VEGFA vascular endothelial growth factor A 2.88009
IL23R interleukin 23 receptor 2.88009
IL23A interleukin 23, alpha subunit p19 2.88009
IL12B interleukin 12B 2.88009
IFIH1 interferon induced with helicase C domain 1 2.88009
HLA-C major histocompatibility complex, class I, C 2.88009
TYK2 tyrosine kinase 2 2.88009
NOS2 nitric oxide synthase 2, inducible 2.88009
ERAP1 endoplasmic reticulum aminopeptidase 1 2.88009
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 2.88009
TP53 tumor protein p53 2.88009
CAT catalase 2.88009
TNIP1 TNFAIP3 interacting protein 1 2.88009
CP ceruloplasmin (ferroxidase) 2.88009
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.88009
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.88009
CARM1 coactivator-associated arginine methyltransferase 1 2.88009
PSORS11 Psoriasis susceptibility 11 2.88009
PSORS10 psoriasis susceptibility 10 2.88009
LCE3D late cornified envelope 3D 2.88009
LCE3B late cornified envelope 3B 2.88009
CYP2S1 cytochrome P450, family 2, subfamily S, polypeptide 1 2.88009
RUNX3 runt-related transcription factor 3 2.88009
IL4 interleukin 4 2.88009
CSMD1 CUB and Sushi multiple domains 1 2.88009
GJB2 gap junction protein, beta 2, 26kDa 2.88009
ZNF816 zinc finger protein 816 2.88009
PPARG peroxisome proliferator-activated receptor gamma 2.88009
CARD14 caspase recruitment domain family, member 14 2.88009
PTTG1 pituitary tumor-transforming 1 2.88009
IFNLR1 interferon, lambda receptor 1 2.88009
IL6 interleukin 6 2.88009
LCE3C late cornified envelope 3C 2.88009
APOE apolipoprotein E 2.88009
VNN2 vanin 2 2.88009
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.88009
PSORS3 psoriasis susceptibility 3 2.88009
TAGAP T-cell activation RhoGTPase activating protein 2.88009
SOD2 superoxide dismutase 2, mitochondrial 2.88009
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 2.88009
IL1B interleukin 1, beta 2.88009
PSORS9 psoriasis susceptibility 9 2.88009
IL13 interleukin 13 2.88009
VNN3 vanin 3 2.88009
ZC3H12C zinc finger CCCH-type containing 12C 2.88009
PSORS4 psoriasis susceptibility 4 2.88009
PSORS6 psoriasis susceptibility 6 2.88009
PSORS8 psoriasis susceptibility 8 2.88009
PSORS7 psoriasis susceptibility 7 2.88009
TGFA transforming growth factor, alpha 2.88009
TNF tumor necrosis factor 2.88009
FBXL19 F-box and leucine-rich repeat protein 19 2.88009
PCNA proliferating cell nuclear antigen 2.88009
PSORS5 psoriasis susceptibility 5 2.88009
VNN1 vanin 1 2.88009
IFNG interferon, gamma 1.46935
FAS Fas cell surface death receptor 1.46621
IL2 interleukin 2 1.37275
IGFBP3 insulin-like growth factor binding protein 3 1.3716
CCL2 chemokine (C-C motif) ligand 2 1.35473
BAX BCL2-associated X protein 1.32547
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.32428
FKBP5 FK506 binding protein 5 1.32428
S100A9 S100 calcium binding protein A9 1.30635
ECH1 enoyl CoA hydratase 1, peroxisomal 1.2772
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.27471
MAPK3 mitogen-activated protein kinase 3 1.2596
DUSP10 dual specificity phosphatase 10 1.25245
MAPK1 mitogen-activated protein kinase 1 1.24623
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.24244
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.22469
MAPK8 mitogen-activated protein kinase 8 1.21468
BCL2 B-cell CLL/lymphoma 2 1.17827
LSP1 lymphocyte-specific protein 1 1.1753
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.17067
CD68 CD68 molecule 1.169
S100A8 S100 calcium binding protein A8 1.16401
GSTP1 glutathione S-transferase pi 1 1.15865
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.15729
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.12973
IL3 interleukin 3 1.11431
CXCL8 chemokine (C-X-C motif) ligand 8 1.11116
UBE2C ubiquitin-conjugating enzyme E2C 1.1014
IL1A interleukin 1, alpha 1.09822
BTG2 BTG family, member 2 1.09506
GSK3B glycogen synthase kinase 3 beta 1.09262
ODC1 ornithine decarboxylase 1 1.08655
TGFB1 transforming growth factor, beta 1 1.08442
TAGLN transgelin 1.08301
TIMP1 TIMP metallopeptidase inhibitor 1 1.08126
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.08019
MMP3 matrix metallopeptidase 3 1.07732
IL10 interleukin 10 1.06771
IGFBP5 insulin-like growth factor binding protein 5 1.06552
RARB retinoic acid receptor, beta 1.06297
IL17RB interleukin 17 receptor B 1.059
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.05089
CCL3 chemokine (C-C motif) ligand 3 1.04941
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 1.04611
MMP2 matrix metallopeptidase 2 1.04611
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 1.04389
RUNX2 runt-related transcription factor 2 1.04352
CCL4 chemokine (C-C motif) ligand 4 1.03864
HMOX1 heme oxygenase 1 1.03567
CCND1 cyclin D1 1.0353
IL1RL1 interleukin 1 receptor-like 1 1.02634
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.02299
MUCL1 mucin-like 1 1.02262
CSF1 colony stimulating factor 1 (macrophage) 1.01399
RRM2 ribonucleotide reductase M2 1.01212
IRS1 insulin receptor substrate 1 1.01212