Psoriasis vulgaris_Skin tissue_GSE6710 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE6710
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Genes

600 genes differentially expressed during Psoriasis vulgaris_Skin tissue_GSE6710 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
KCTD5 potassium channel tetramerization domain containing 5 3.57452
MLX MLX, MAX dimerization protein 3.15284
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 3.12157
S100A12 S100 calcium binding protein A12 3.03106
HMOX1 heme oxygenase 1 2.88354
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.77551
LIMK2 LIM domain kinase 2 2.77407
TPBG trophoblast glycoprotein 2.76316
SRSF9 serine/arginine-rich splicing factor 9 2.75246
PLCD1 phospholipase C, delta 1 2.72315
ZC3H12A zinc finger CCCH-type containing 12A 2.71824
HPSE heparanase 2.70604
SFT2D2 SFT2 domain containing 2 2.68152
CARHSP1 calcium regulated heat stable protein 1, 24kDa 2.67912
LYN LYN proto-oncogene, Src family tyrosine kinase 2.59962
ALOX12B arachidonate 12-lipoxygenase, 12R type 2.59696
IL4R interleukin 4 receptor 2.55854
TLE3 transducin-like enhancer of split 3 2.51834
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.48012
IRF1 interferon regulatory factor 1 2.45806
RPN2 ribophorin II 2.45803
SMOX spermine oxidase 2.4336
MKI67 marker of proliferation Ki-67 2.40269
SRPK1 SRSF protein kinase 1 2.36943
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 2.34974
CCNB1 cyclin B1 2.33839
IL36RN interleukin 36 receptor antagonist 2.33379
TMEM110 transmembrane protein 110 2.3013
TUBB6 tubulin, beta 6 class V 2.29561
DLX5 distal-less homeobox 5 2.28112
GYS1 glycogen synthase 1 (muscle) 2.2796
TREX2 three prime repair exonuclease 2 2.27578
N4BP1 NEDD4 binding protein 1 2.26815
PPARD peroxisome proliferator-activated receptor delta 2.26299
ZBTB5 zinc finger and BTB domain containing 5 2.25858
PRSS2 protease, serine, 2 (trypsin 2) 2.25492
MAPK13 mitogen-activated protein kinase 13 2.24002
SUSD6 sushi domain containing 6 2.23975
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 2.2302
CD53 CD53 molecule 2.2291
ITSN2 intersectin 2 2.22072
SMAGP small cell adhesion glycoprotein 2.21728
TMED9 transmembrane emp24 protein transport domain containing 9 2.21281
MAP2K3 mitogen-activated protein kinase kinase 3 2.20487
TGM3 transglutaminase 3 2.20275
AGFG1 ArfGAP with FG repeats 1 2.20086
GSTP1 glutathione S-transferase pi 1 2.19903
CCDC109B coiled-coil domain containing 109B 2.1977
SLC39A11 solute carrier family 39, member 11 2.18775
MID1IP1 MID1 interacting protein 1 2.17343
HDGF hepatoma-derived growth factor 2.15197
NUP37 nucleoporin 37kDa 2.149
MAEA macrophage erythroblast attacher 2.1488
TMEM30B transmembrane protein 30B 2.14375
GINS3 GINS complex subunit 3 (Psf3 homolog) 2.14203
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 2.1311
CENPA centromere protein A 2.12821
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 2.11033
PTTG1 pituitary tumor-transforming 1 2.09682
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 2.0691
KIF2C kinesin family member 2C 2.06199
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 2.04637
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 2.03987
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 2.03982
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.03917
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 2.03906
PYCARD PYD and CARD domain containing 2.02801
CCNB2 cyclin B2 2.02566
PTBP1 polypyrimidine tract binding protein 1 2.02329
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 2.02045
CD24 CD24 molecule 2.02045
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 2.01841
TOX4 TOX high mobility group box family member 4 2.01385
MAP3K9 mitogen-activated protein kinase kinase kinase 9 2.00975
GM2A GM2 ganglioside activator 2.00866
ARF3 ADP-ribosylation factor 3 2.00859
ARPC5L actin related protein 2/3 complex, subunit 5-like 2.00742
VCP valosin containing protein 2.00723
CYB5R4 cytochrome b5 reductase 4 2.00215
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 1.99342
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 1.99137
RGS20 regulator of G-protein signaling 20 1.98959
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 1.98111
AURKA aurora kinase A 1.981
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.97049
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 1.96291
NAMPT nicotinamide phosphoribosyltransferase 1.96201
CDKN3 cyclin-dependent kinase inhibitor 3 1.96145
YAF2 YY1 associated factor 2 1.95898
RAB11A RAB11A, member RAS oncogene family 1.9567
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.95401
UBE2H ubiquitin-conjugating enzyme E2H 1.9538
PRSS3P2 protease, serine, 3 pseudogene 2 1.94262
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 1.94102
PGAM1 phosphoglycerate mutase 1 (brain) 1.93657
EPHA2 EPH receptor A2 1.93656
EPN3 epsin 3 1.93102
IFT57 intraflagellar transport 57 1.91542
LEPROTL1 leptin receptor overlapping transcript-like 1 1.91444
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 1.9054
EIF4A3 eukaryotic translation initiation factor 4A3 1.9008
PREP prolyl endopeptidase 1.90046
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 1.8955
HDAC1 histone deacetylase 1 1.89359
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 1.89333
CTSB cathepsin B 1.88669
DEDD death effector domain containing 1.88578
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.8854
LRP10 low density lipoprotein receptor-related protein 10 1.87795
C20ORF24 chromosome 20 open reading frame 24 1.87656
WNT5A wingless-type MMTV integration site family, member 5A 1.86082
GARS glycyl-tRNA synthetase 1.85897
RIMS3 regulating synaptic membrane exocytosis 3 1.85755
ZNF207 zinc finger protein 207 1.84496
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 1.84492
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 1.8434
GTPBP2 GTP binding protein 2 1.82889
TMEM40 transmembrane protein 40 1.82619
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 1.82081
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 1.81271
SQRDL sulfide quinone reductase-like (yeast) 1.80935
TOLLIP toll interacting protein 1.80881
PPIF peptidylprolyl isomerase F 1.80682
PRSS3 protease, serine, 3 1.80409
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 1.79616
MFSD4 major facilitator superfamily domain containing 4 1.79323
ELAVL1 ELAV like RNA binding protein 1 1.78447
AK2 adenylate kinase 2 1.78181
ANAPC1 anaphase promoting complex subunit 1 1.78146
BLNK B-cell linker 1.78004
UBE2N ubiquitin-conjugating enzyme E2N 1.77784
CLEC7A C-type lectin domain family 7, member A 1.77129
TRIP13 thyroid hormone receptor interactor 13 1.77102
FBXO9 F-box protein 9 1.76719
TDP2 tyrosyl-DNA phosphodiesterase 2 1.76589
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 1.76526
MRPL17 mitochondrial ribosomal protein L17 1.75564
UBE2G1 ubiquitin-conjugating enzyme E2G 1 1.7495
RAB25 RAB25, member RAS oncogene family 1.74931
CD47 CD47 molecule 1.74918
LYPD3 LY6/PLAUR domain containing 3 1.74662
KLK8 kallikrein-related peptidase 8 1.74618
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 1.74256
IGSF3 immunoglobulin superfamily, member 3 1.73824
PGLYRP4 peptidoglycan recognition protein 4 1.73665
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 1.73509
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 1.73447
PLAT plasminogen activator, tissue 1.73193
MREG melanoregulin 1.72924
BCR breakpoint cluster region 1.72367
H2AFY H2A histone family, member Y 1.71851
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.71821
TDP1 tyrosyl-DNA phosphodiesterase 1 1.71699
ACP5 acid phosphatase 5, tartrate resistant 1.71609
JUNB jun B proto-oncogene 1.71369
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 1.71309
MPZL1 myelin protein zero-like 1 1.71223
PDZK1IP1 PDZK1 interacting protein 1 1.7102
IL1RN interleukin 1 receptor antagonist 1.70642
KYNU kynureninase 1.70413
TGM1 transglutaminase 1 1.70019
NDEL1 nudE neurodevelopment protein 1-like 1 1.7001
UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.69996
TRAPPC3 trafficking protein particle complex 3 1.6955
ALG3 ALG3, alpha-1,3- mannosyltransferase 1.69362
SFN stratifin 1.69055
TRIM15 tripartite motif containing 15 1.68506
LGALS8 lectin, galactoside-binding, soluble, 8 1.68181
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.66915
KLK13 kallikrein-related peptidase 13 1.66827
DAZAP1 DAZ associated protein 1 1.66071
LPXN leupaxin 1.65896
NUP50 nucleoporin 50kDa 1.65846
GCH1 GTP cyclohydrolase 1 1.65736
KLK10 kallikrein-related peptidase 10 1.6569
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 1.65515
GBAP1 glucosidase, beta, acid pseudogene 1 1.64576
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.63901
CDC25B cell division cycle 25B 1.63815
EPHA1 EPH receptor A1 1.6368
CALR calreticulin 1.63592
PTS 6-pyruvoyltetrahydropterin synthase 1.6296
PBK PDZ binding kinase 1.62639
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 1.62419
DDRGK1 DDRGK domain containing 1 1.62376
ITCH itchy E3 ubiquitin protein ligase 1.6233
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 1.623
MYD88 myeloid differentiation primary response 88 1.62065
HRAS Harvey rat sarcoma viral oncogene homolog 1.62004
STX6 syntaxin 6 1.61493
CYB561D2 cytochrome b561 family, member D2 1.61267
MRPL15 mitochondrial ribosomal protein L15 1.61038
CSNK1A1 casein kinase 1, alpha 1 1.60896
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 1.60717
SFXN1 sideroflexin 1 1.60685
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 1.60385
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 1.60181
CFLAR CASP8 and FADD-like apoptosis regulator 1.59409
C12ORF49 chromosome 12 open reading frame 49 1.59351
EPHX3 epoxide hydrolase 3 1.59316
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 1.58992
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 1.58866
MAPK14 mitogen-activated protein kinase 14 1.58686
UBE2S ubiquitin-conjugating enzyme E2S 1.58656
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 1.58485
PLCG1 phospholipase C, gamma 1 1.58437
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 1.58204
C19ORF66 chromosome 19 open reading frame 66 1.58092
EIF3J eukaryotic translation initiation factor 3, subunit J 1.57976
ACOX3 acyl-CoA oxidase 3, pristanoyl 1.57949
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 1.57265
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.57179
WDR55 WD repeat domain 55 1.56707
OLFM1 olfactomedin 1 1.56659
CXCR4 chemokine (C-X-C motif) receptor 4 1.56203
PMM2 phosphomannomutase 2 1.5585
ZSCAN4 zinc finger and SCAN domain containing 4 1.55704
SUMO3 small ubiquitin-like modifier 3 1.55613
BCL3 B-cell CLL/lymphoma 3 1.55074
XPO6 exportin 6 1.54987
ABT1 activator of basal transcription 1 1.54941
BAK1 BCL2-antagonist/killer 1 1.54641
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.54633
YAP1 Yes-associated protein 1 1.54511
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) 1.54402
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.54146
PNP purine nucleoside phosphorylase 1.53979
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 1.53806
WHSC1 Wolf-Hirschhorn syndrome candidate 1 1.53685
IRF9 interferon regulatory factor 9 1.53454
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 1.53265
WWOX WW domain containing oxidoreductase 1.53239
TNPO1 transportin 1 1.53184
LAD1 ladinin 1 1.52698
PITPNA phosphatidylinositol transfer protein, alpha 1.52401
HMOX2 heme oxygenase 2 1.52128
UBL4A ubiquitin-like 4A 1.51928
MRPS2 mitochondrial ribosomal protein S2 1.50872
OASL 2'-5'-oligoadenylate synthetase-like 1.49958
ADAP2 ArfGAP with dual PH domains 2 1.49893
NAGA N-acetylgalactosaminidase, alpha- 1.49834
CRABP2 cellular retinoic acid binding protein 2 1.49595
CTSA cathepsin A 1.49593
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 1.49592
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 1.49481
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 1.48343
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.47872
NRBF2 nuclear receptor binding factor 2 1.47859
CARD14 caspase recruitment domain family, member 14 1.47826
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.47305
HARS histidyl-tRNA synthetase 1.47119
CSNK1E casein kinase 1, epsilon 1.47068
PA2G4 proliferation-associated 2G4, 38kDa 1.47026
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 1.46617
KCMF1 potassium channel modulatory factor 1 1.46562
KIF18B kinesin family member 18B 1.46317
PDF peptide deformylase (mitochondrial) 1.46183
ITPKC inositol-trisphosphate 3-kinase C 1.4617
RGS14 regulator of G-protein signaling 14 1.45949
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 1.4569
MTSS1 metastasis suppressor 1 1.45653
EPHB2 EPH receptor B2 1.45591
TFEC transcription factor EC 1.45578
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 1.45468
WBSCR16 Williams-Beuren syndrome chromosome region 16 1.45188
MAPKAP1 mitogen-activated protein kinase associated protein 1 1.45037
PRSS53 protease, serine, 53 1.44536
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 1.44254
CKS2 CDC28 protein kinase regulatory subunit 2 1.44128
SLC25A44 solute carrier family 25, member 44 1.44089
OAZ1 ornithine decarboxylase antizyme 1 1.43652
CTSC cathepsin C 1.43508
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 1.4344
MELK maternal embryonic leucine zipper kinase 1.43379
ACOT11 acyl-CoA thioesterase 11 1.42772
SOD2 superoxide dismutase 2, mitochondrial 1.42763
TRIM62 tripartite motif containing 62 1.42643
MRPL13 mitochondrial ribosomal protein L13 1.42582
FKBP15 FK506 binding protein 15, 133kDa 1.42355
UBE2A ubiquitin-conjugating enzyme E2A 1.42199
FAM102A family with sequence similarity 102, member A 1.42031
PRDM1 PR domain containing 1, with ZNF domain 1.41894
PGBD5 piggyBac transposable element derived 5 1.41878
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 1.41809
TFG TRK-fused gene 1.41569
FOSL2 FOS-like antigen 2 1.41474
ERCC1 excision repair cross-complementation group 1 1.41408
MED8 mediator complex subunit 8 1.41349
NIPSNAP1 nipsnap homolog 1 (C. elegans) 1.41168
FGFBP1 fibroblast growth factor binding protein 1 1.40993
IFI16 interferon, gamma-inducible protein 16 1.40891
SEC61B Sec61 beta subunit 1.40879
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 1.40641
GRN granulin 1.40579
DESI2 desumoylating isopeptidase 2 1.4043
RND3 Rho family GTPase 3 1.40425
RUSC1 RUN and SH3 domain containing 1 1.4036
C6ORF223 chromosome 6 open reading frame 223 1.4018
INA internexin neuronal intermediate filament protein, alpha 1.40079
PDK3 pyruvate dehydrogenase kinase, isozyme 3 1.39949

decreased expression

Symbol Name Standardized Value
ACAT1 acetyl-CoA acetyltransferase 1 -3.5385
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -3.08569
EIF3H eukaryotic translation initiation factor 3, subunit H -3.02981
SOD1 superoxide dismutase 1, soluble -2.99632
NFE2L1 nuclear factor, erythroid 2-like 1 -2.94095
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -2.89307
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 -2.78503
CIRBP cold inducible RNA binding protein -2.74717
TUFT1 tuftelin 1 -2.74135
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -2.68413
TMEM87A transmembrane protein 87A -2.68153
NRD1 nardilysin (N-arginine dibasic convertase) -2.5807
C9ORF78 chromosome 9 open reading frame 78 -2.53874
BAG1 BCL2-associated athanogene -2.52842
CHMP3 charged multivesicular body protein 3 -2.49133
ATXN7L3B ataxin 7-like 3B -2.47138
EAPP E2F-associated phosphoprotein -2.42729
SAP18 Sin3A-associated protein, 18kDa -2.38997
C11ORF57 chromosome 11 open reading frame 57 -2.37479
ILK integrin-linked kinase -2.34853
PEBP1 phosphatidylethanolamine binding protein 1 -2.33779
ATXN10 ataxin 10 -2.3275
FOXO1 forkhead box O1 -2.32401
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -2.31973
SKP1 S-phase kinase-associated protein 1 -2.29803
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -2.29765
SPHAR S-phase response (cyclin related) -2.28175
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -2.275
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -2.27478
TMEM43 transmembrane protein 43 -2.2514
SUMO1 small ubiquitin-like modifier 1 -2.24483
VTI1B vesicle transport through interaction with t-SNAREs 1B -2.22966
SETD3 SET domain containing 3 -2.22581
SEPT7 septin 7 -2.21425
GOLGA7 golgin A7 -2.20367
ERMAP erythroblast membrane-associated protein (Scianna blood group) -2.19912
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.19237
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -2.18584
PFDN5 prefoldin subunit 5 -2.18387
AP1S2 adaptor-related protein complex 1, sigma 2 subunit -2.17877
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa -2.16595
DGUOK deoxyguanosine kinase -2.16423
CSDE1 cold shock domain containing E1, RNA-binding -2.14774
OSBP oxysterol binding protein -2.13826
PARL presenilin associated, rhomboid-like -2.13508
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.13495
FAM134A family with sequence similarity 134, member A -2.12594
FAM131A family with sequence similarity 131, member A -2.09928
ADRB2 adrenoceptor beta 2, surface -2.09924
AHCYL2 adenosylhomocysteinase-like 2 -2.0854
HEBP2 heme binding protein 2 -2.07026
EIF3L eukaryotic translation initiation factor 3, subunit L -2.0666
RTN3 reticulon 3 -2.06277
CD59 CD59 molecule, complement regulatory protein -2.05816
CDC37L1 cell division cycle 37-like 1 -2.05336
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -2.04958
CBX1 chromobox homolog 1 -2.01787
CTNNBIP1 catenin, beta interacting protein 1 -2.01444
PJA1 praja ring finger 1, E3 ubiquitin protein ligase -1.99953
ATP6V0E2 ATPase, H+ transporting V0 subunit e2 -1.988
PHYH phytanoyl-CoA 2-hydroxylase -1.98092
ANKMY2 ankyrin repeat and MYND domain containing 2 -1.96799
FTSJ3 FtsJ homolog 3 (E. coli) -1.9676
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -1.9648
HAGH hydroxyacylglutathione hydrolase -1.96354
DIABLO diablo, IAP-binding mitochondrial protein -1.96159
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -1.95926
GGNBP2 gametogenetin binding protein 2 -1.95851
TMEM109 transmembrane protein 109 -1.95296
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -1.94727
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 -1.93805
CASC3 cancer susceptibility candidate 3 -1.93516
CSRP1 cysteine and glycine-rich protein 1 -1.93453
IRF6 interferon regulatory factor 6 -1.93162
TCEA1 transcription elongation factor A (SII), 1 -1.92816
GGPS1 geranylgeranyl diphosphate synthase 1 -1.92189
CDC16 cell division cycle 16 -1.9171
SERTAD2 SERTA domain containing 2 -1.90726
TCTE1 t-complex-associated-testis-expressed 1 -1.89924
MUT methylmalonyl CoA mutase -1.88683
RNF38 ring finger protein 38 -1.88499
WDR47 WD repeat domain 47 -1.88371
SNRK SNF related kinase -1.8784
DYNLRB1 dynein, light chain, roadblock-type 1 -1.86936
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -1.8617
TTC19 tetratricopeptide repeat domain 19 -1.8612
IL20RB interleukin 20 receptor beta -1.86092
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 -1.85795
LAPTM4A lysosomal protein transmembrane 4 alpha -1.85293
FBL fibrillarin -1.85185
EIF3E eukaryotic translation initiation factor 3, subunit E -1.85071
IFT52 intraflagellar transport 52 -1.85036
DAAM2 dishevelled associated activator of morphogenesis 2 -1.85034
MOAP1 modulator of apoptosis 1 -1.84691
SEC11A SEC11 homolog A (S. cerevisiae) -1.8422
CTNND1 catenin (cadherin-associated protein), delta 1 -1.84105
GLO1 glyoxalase I -1.84077
AHNAK2 AHNAK nucleoprotein 2 -1.83948
IGBP1 immunoglobulin (CD79A) binding protein 1 -1.82492
CADPS2 Ca++-dependent secretion activator 2 -1.82289
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein -1.82178
MIA3 melanoma inhibitory activity family, member 3 -1.82052
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -1.81291
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -1.81198
KLF11 Kruppel-like factor 11 -1.80163
GLUD1 glutamate dehydrogenase 1 -1.79846
PLS3 plastin 3 -1.79734
PHLDA3 pleckstrin homology-like domain, family A, member 3 -1.79429
ELL3 elongation factor RNA polymerase II-like 3 -1.79332
UBE4A ubiquitination factor E4A -1.78687
XPA xeroderma pigmentosum, complementation group A -1.78094
INSIG2 insulin induced gene 2 -1.77865
CERS6 ceramide synthase 6 -1.77462
H2AFJ H2A histone family, member J -1.77174
ITPKB inositol-trisphosphate 3-kinase B -1.76283
MADD MAP-kinase activating death domain -1.76206
SF3A3 splicing factor 3a, subunit 3, 60kDa -1.76009
EXOSC7 exosome component 7 -1.75966
PEX7 peroxisomal biogenesis factor 7 -1.75464
HEBP1 heme binding protein 1 -1.75353
TP53BP2 tumor protein p53 binding protein 2 -1.7515
DRG1 developmentally regulated GTP binding protein 1 -1.74668
MRPS14 mitochondrial ribosomal protein S14 -1.74097
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae) -1.74063
AP3M2 adaptor-related protein complex 3, mu 2 subunit -1.73797
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -1.7347
SEPHS1 selenophosphate synthetase 1 -1.72768
PHKB phosphorylase kinase, beta -1.72737
SMAD2 SMAD family member 2 -1.72359
POLD3 polymerase (DNA-directed), delta 3, accessory subunit -1.71936
LIPT1 lipoyltransferase 1 -1.71538
CREBL2 cAMP responsive element binding protein-like 2 -1.71482
HECA headcase homolog (Drosophila) -1.71074
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -1.70695
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -1.70673
MAP4 microtubule-associated protein 4 -1.70477
BBS1 Bardet-Biedl syndrome 1 -1.69106
COBL cordon-bleu WH2 repeat protein -1.6885
UFM1 ubiquitin-fold modifier 1 -1.68642
KIAA0368 KIAA0368 -1.67885
UBE2D2 ubiquitin-conjugating enzyme E2D 2 -1.67259
UFSP2 UFM1-specific peptidase 2 -1.66864
PARVA parvin, alpha -1.66311
DDB1 damage-specific DNA binding protein 1, 127kDa -1.66188
B3GNT1 -1.65935
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -1.65768
CCT4 chaperonin containing TCP1, subunit 4 (delta) -1.65666
PCNP PEST proteolytic signal containing nuclear protein -1.65171
SESN1 sestrin 1 -1.64707
CUEDC2 CUE domain containing 2 -1.64396
KARS lysyl-tRNA synthetase -1.63723
SCCPDH saccharopine dehydrogenase (putative) -1.63571
UXT ubiquitously-expressed, prefoldin-like chaperone -1.63262
PEX12 peroxisomal biogenesis factor 12 -1.63077
RYK receptor-like tyrosine kinase -1.62519
DAZAP2 DAZ associated protein 2 -1.62353
H2AFV H2A histone family, member V -1.62204
TTC28 tetratricopeptide repeat domain 28 -1.61912
BRD1 bromodomain containing 1 -1.6172
MRPS27 mitochondrial ribosomal protein S27 -1.61205
TRMT5 tRNA methyltransferase 5 -1.60767
POLR1E polymerase (RNA) I polypeptide E, 53kDa -1.60726
TUBGCP4 tubulin, gamma complex associated protein 4 -1.60542
DAD1 defender against cell death 1 -1.60288
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -1.6021
LAPTM4B lysosomal protein transmembrane 4 beta -1.60138
AATF apoptosis antagonizing transcription factor -1.59847
SETMAR SET domain and mariner transposase fusion gene -1.59606
TLK2 tousled-like kinase 2 -1.59605
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -1.59502
DDAH1 dimethylarginine dimethylaminohydrolase 1 -1.59401
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative) -1.58759
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -1.58251
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa -1.58208
ZNF7 zinc finger protein 7 -1.58171
DDHD2 DDHD domain containing 2 -1.58008
ZNF143 zinc finger protein 143 -1.57825
SNW1 SNW domain containing 1 -1.57573
MAGEF1 melanoma antigen family F1 -1.5746
TRIAP1 TP53 regulated inhibitor of apoptosis 1 -1.57188
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -1.57171
SPAG16 sperm associated antigen 16 -1.57102
TSPAN14 tetraspanin 14 -1.56885
UGP2 UDP-glucose pyrophosphorylase 2 -1.56838
ZNF629 zinc finger protein 629 -1.56795
ERGIC3 ERGIC and golgi 3 -1.56662
C14ORF166 chromosome 14 open reading frame 166 -1.56643
GLOD4 glyoxalase domain containing 4 -1.56609
LMCD1 LIM and cysteine-rich domains 1 -1.56173
ZNF395 zinc finger protein 395 -1.56159
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) -1.56067
FLNC filamin C, gamma -1.55851
CLNS1A chloride channel, nucleotide-sensitive, 1A -1.55622
FLII flightless I homolog (Drosophila) -1.55381
TM2D3 TM2 domain containing 3 -1.55378
EIF1B eukaryotic translation initiation factor 1B -1.55284
MATN2 matrilin 2 -1.55003
CUTA cutA divalent cation tolerance homolog (E. coli) -1.54903
STX8 syntaxin 8 -1.54876
DHDDS dehydrodolichyl diphosphate synthase -1.54624
NOTCH2 notch 2 -1.53879
GTF3A general transcription factor IIIA -1.5385
KLHDC2 kelch domain containing 2 -1.53837
CKB creatine kinase, brain -1.53621
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -1.53568
ACTA2 actin, alpha 2, smooth muscle, aorta -1.53512
RTN4 reticulon 4 -1.53504
JAK1 Janus kinase 1 -1.52785
GOLGA3 golgin A3 -1.52648
ZNF410 zinc finger protein 410 -1.52523
GRHPR glyoxylate reductase/hydroxypyruvate reductase -1.52522
INPP5F inositol polyphosphate-5-phosphatase F -1.52399
TTC4 tetratricopeptide repeat domain 4 -1.52391
TLE2 transducin-like enhancer of split 2 -1.51806
SYNGR2 synaptogyrin 2 -1.51714
QDPR quinoid dihydropteridine reductase -1.51667
OPTN optineurin -1.51455
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -1.51372
DNMBP dynamin binding protein -1.51101
TMEM59 transmembrane protein 59 -1.50906
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -1.50691
CRY2 cryptochrome circadian clock 2 -1.50552
EIF4E1B eukaryotic translation initiation factor 4E family member 1B -1.50528
UBE2Z ubiquitin-conjugating enzyme E2Z -1.50406
PGRMC2 progesterone receptor membrane component 2 -1.50289
EID1 EP300 interacting inhibitor of differentiation 1 -1.50197
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -1.49853
SNURF SNRPN upstream reading frame -1.49587
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) -1.49047
PMS2P3 postmeiotic segregation increased 2 pseudogene 3 -1.49046
NRN1 neuritin 1 -1.48999
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -1.48854
TMEM186 transmembrane protein 186 -1.48703
GMDS GDP-mannose 4,6-dehydratase -1.48596
NAP1L3 nucleosome assembly protein 1-like 3 -1.48393
DNASE2 deoxyribonuclease II, lysosomal -1.48114
LTA4H leukotriene A4 hydrolase -1.48112
SLC2A4RG SLC2A4 regulator -1.47969
RPL15 ribosomal protein L15 -1.47734
UBAC1 UBA domain containing 1 -1.47689
RAB4A RAB4A, member RAS oncogene family -1.4751
PTPRM protein tyrosine phosphatase, receptor type, M -1.47488
PARK7 parkinson protein 7 -1.47435
NGRN neugrin, neurite outgrowth associated -1.47319
BCHE butyrylcholinesterase -1.46863
ADAMTSL3 ADAMTS-like 3 -1.46677
KLC1 kinesin light chain 1 -1.46642
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -1.46536
RRAGD Ras-related GTP binding D -1.46255
SSFA2 sperm specific antigen 2 -1.46213
FBXO7 F-box protein 7 -1.46033
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -1.4601
HAUS4 HAUS augmin-like complex, subunit 4 -1.45806
METTL13 methyltransferase like 13 -1.45421
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -1.45337
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -1.45111
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -1.44526
ARL3 ADP-ribosylation factor-like 3 -1.44338
C14ORF132 chromosome 14 open reading frame 132 -1.44146
TPM1 tropomyosin 1 (alpha) -1.44002
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -1.43905
KIAA0355 KIAA0355 -1.43402
RCAN2 regulator of calcineurin 2 -1.43234
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -1.43109
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) -1.43081
LYRM9 LYR motif containing 9 -1.43028
YPEL5 yippee-like 5 (Drosophila) -1.42998
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) -1.4275
FOXJ2 forkhead box J2 -1.42603
ANXA2 annexin A2 -1.42376
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 -1.42054
NCOA4 nuclear receptor coactivator 4 -1.41919
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) -1.41891
COMMD3 COMM domain containing 3 -1.41666
BPHL biphenyl hydrolase-like (serine hydrolase) -1.41396
HOXC6 homeobox C6 -1.41386
CEP68 centrosomal protein 68kDa -1.41252
ESD esterase D -1.40863
ESYT1 extended synaptotagmin-like protein 1 -1.40575
SF3B2 splicing factor 3b, subunit 2, 145kDa -1.40571
SETD2 SET domain containing 2 -1.40557
MAGED2 melanoma antigen family D2 -1.40556
ANXA7 annexin A7 -1.40543
LMBRD1 LMBR1 domain containing 1 -1.40348
MRFAP1L1 Morf4 family associated protein 1-like 1 -1.40317
RWDD1 RWD domain containing 1 -1.4017
CCDC93 coiled-coil domain containing 93 -1.40052
PFN2 profilin 2 -1.39981
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 -1.39966
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -1.39935
HLF hepatic leukemia factor -1.39777
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 -1.3964
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -1.39506
NBR1 neighbor of BRCA1 gene 1 -1.39367
GSPT2 G1 to S phase transition 2 -1.39248
SYF2 SYF2 pre-mRNA-splicing factor -1.39236
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -1.39028
CCDC25 coiled-coil domain containing 25 -1.38766
EBAG9 estrogen receptor binding site associated, antigen, 9 -1.38694
WFS1 Wolfram syndrome 1 (wolframin) -1.38288