Protozoan Infection_Intestinal Epithelium_GSE2077 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2077
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Genes

600 genes differentially expressed during Protozoan Infection_Intestinal Epithelium_GSE2077 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
ERCC3 excision repair cross-complementation group 3 3.31235
SAFB2 scaffold attachment factor B2 3.31166
GSR glutathione reductase 3.109
SAP18 Sin3A-associated protein, 18kDa 3.1013
MAPRE1 microtubule-associated protein, RP/EB family, member 1 3.06204
ALAS1 5'-aminolevulinate synthase 1 3.03302
CCND2 cyclin D2 2.9525
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.89272
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.84591
IL4R interleukin 4 receptor 2.82161
SEC13 SEC13 homolog (S. cerevisiae) 2.81186
RAB8A RAB8A, member RAS oncogene family 2.76005
TXLNA taxilin alpha 2.74651
TUBG1 tubulin, gamma 1 2.74212
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.71526
RTN4 reticulon 4 2.70594
RALB v-ral simian leukemia viral oncogene homolog B 2.68536
WDR1 WD repeat domain 1 2.65337
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.64909
PDIA5 protein disulfide isomerase family A, member 5 2.6018
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.59451
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.58641
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.58101
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 2.57647
GOSR1 golgi SNAP receptor complex member 1 2.57404
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 2.52723
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 2.50515
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 2.49699
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.49415
NECAP1 NECAP endocytosis associated 1 2.47208
TPST2 tyrosylprotein sulfotransferase 2 2.47131
MYB v-myb avian myeloblastosis viral oncogene homolog 2.46149
ETFDH electron-transferring-flavoprotein dehydrogenase 2.4299
MORF4L2 mortality factor 4 like 2 2.42366
UBE2E3 ubiquitin-conjugating enzyme E2E 3 2.39202
PDCD6 programmed cell death 6 2.38394
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 2.37103
GCH1 GTP cyclohydrolase 1 2.35405
TACSTD2 tumor-associated calcium signal transducer 2 2.34104
TOMM34 translocase of outer mitochondrial membrane 34 2.34096
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.33892
NQO2 NAD(P)H dehydrogenase, quinone 2 2.30902
IL15RA interleukin 15 receptor, alpha 2.30521
MFAP1 microfibrillar-associated protein 1 2.30251
EPCAM epithelial cell adhesion molecule 2.29498
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 2.29043
CDK11A cyclin-dependent kinase 11A 2.28958
NUP62 nucleoporin 62kDa 2.2815
NMI N-myc (and STAT) interactor 2.28049
TSC22D1 TSC22 domain family, member 1 2.27334
SUMO2 small ubiquitin-like modifier 2 2.26636
UCK2 uridine-cytidine kinase 2 2.25853
PLAUR plasminogen activator, urokinase receptor 2.24546
VDAC1 voltage-dependent anion channel 1 2.23342
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.22458
CDC6 cell division cycle 6 2.21758
CCNO cyclin O 2.20106
PVR poliovirus receptor 2.19079
VAMP3 vesicle-associated membrane protein 3 2.1802
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 2.1704
CREB3 cAMP responsive element binding protein 3 2.16454
SRP54 signal recognition particle 54kDa 2.16331
ENDOD1 endonuclease domain containing 1 2.15718
PRDX6 peroxiredoxin 6 2.15271
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 2.14786
PRSS22 protease, serine, 22 2.14021
RPP38 ribonuclease P/MRP 38kDa subunit 2.12236
LAPTM4A lysosomal protein transmembrane 4 alpha 2.11751
TSPAN8 tetraspanin 8 2.11395
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa 2.11283
PROSC proline synthetase co-transcribed homolog (bacterial) 2.11025
RALBP1 ralA binding protein 1 2.08418
NCBP2 nuclear cap binding protein subunit 2, 20kDa 2.08397
DKC1 dyskeratosis congenita 1, dyskerin 2.06935
PPAP2B phosphatidic acid phosphatase type 2B 2.06435
PTP4A2 protein tyrosine phosphatase type IVA, member 2 2.05969
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 2.05463
NAGLU N-acetylglucosaminidase, alpha 2.04499
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 2.04016
EED embryonic ectoderm development 2.03841
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 2.03371
UBE2L3 ubiquitin-conjugating enzyme E2L 3 2.03345
CDR2 cerebellar degeneration-related protein 2, 62kDa 2.02726
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 2.02269
HMGN1 high mobility group nucleosome binding domain 1 2.02075
ITGB5 integrin, beta 5 2.01735
HEBP2 heme binding protein 2 1.99449
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 1.99256
GOLGA3 golgin A3 1.98018
GINS1 GINS complex subunit 1 (Psf1 homolog) 1.97933
DUSP3 dual specificity phosphatase 3 1.96978
H2AFY H2A histone family, member Y 1.95164
PTBP1 polypyrimidine tract binding protein 1 1.94913
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.94709
HIST1H1T histone cluster 1, H1t 1.94373
TACC1 transforming, acidic coiled-coil containing protein 1 1.93028
PALLD palladin, cytoskeletal associated protein 1.93003
SRSF4 serine/arginine-rich splicing factor 4 1.92811
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.92707
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 1.92171
DLAT dihydrolipoamide S-acetyltransferase 1.91956
CYCS cytochrome c, somatic 1.91904
SDCBP syndecan binding protein (syntenin) 1.91115
FEN1 flap structure-specific endonuclease 1 1.90672
TM4SF1 transmembrane 4 L six family member 1 1.90486
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 1.90398
TM2D1 TM2 domain containing 1 1.90046
GLA galactosidase, alpha 1.89516
TPM1 tropomyosin 1 (alpha) 1.89327
ELK1 ELK1, member of ETS oncogene family 1.89065
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 1.88279
PITPNB phosphatidylinositol transfer protein, beta 1.88217
EMP2 epithelial membrane protein 2 1.87378
SBNO2 strawberry notch homolog 2 (Drosophila) 1.87098
FAT1 FAT atypical cadherin 1 1.86828
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) 1.86683
LAMP1 lysosomal-associated membrane protein 1 1.86467
AREG amphiregulin 1.86023
GABARAPL2 GABA(A) receptor-associated protein-like 2 1.85582
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.85427
NOLC1 nucleolar and coiled-body phosphoprotein 1 1.85243
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.84606
DPP4 dipeptidyl-peptidase 4 1.84571
DAZAP2 DAZ associated protein 2 1.84481
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 1.84187
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 1.83659
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 1.83617
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.83459
MICB MHC class I polypeptide-related sequence B 1.83268
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 1.83231
HLA-A major histocompatibility complex, class I, A 1.83118
MBD4 methyl-CpG binding domain protein 4 1.82648
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 1.82568
CNOT4 CCR4-NOT transcription complex, subunit 4 1.82429
CLDN4 claudin 4 1.8236
NFYA nuclear transcription factor Y, alpha 1.82279
ZFPL1 zinc finger protein-like 1 1.81613
GLO1 glyoxalase I 1.80948
TUBA3D tubulin, alpha 3d 1.8067
AMPD2 adenosine monophosphate deaminase 2 1.79964
TMED2 transmembrane emp24 domain trafficking protein 2 1.79444
TRIM27 tripartite motif containing 27 1.79411
PLK2 polo-like kinase 2 1.79325
YBX1 Y box binding protein 1 1.79009
TOE1 target of EGR1, member 1 (nuclear) 1.78899
PTRF polymerase I and transcript release factor 1.78061
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 1.77948
DYNLL1 dynein, light chain, LC8-type 1 1.77911
HMGN4 high mobility group nucleosomal binding domain 4 1.77852
NDEL1 nudE neurodevelopment protein 1-like 1 1.76914
ARF4 ADP-ribosylation factor 4 1.76047
CLNS1A chloride channel, nucleotide-sensitive, 1A 1.75276
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 1.74812
PCBP3 poly(rC) binding protein 3 1.7433
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 1.7411
UBE2I ubiquitin-conjugating enzyme E2I 1.73953
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21 1.73929
WRB tryptophan rich basic protein 1.73711
TICAM1 toll-like receptor adaptor molecule 1 1.73465
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 1.73345
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.72483
NMT1 N-myristoyltransferase 1 1.70992
MAMLD1 mastermind-like domain containing 1 1.70877
AGPS alkylglycerone phosphate synthase 1.70737
LUZP1 leucine zipper protein 1 1.70112
NADK NAD kinase 1.70048
RPL7 ribosomal protein L7 1.69698
ALG8 ALG8, alpha-1,3-glucosyltransferase 1.69299
GEM GTP binding protein overexpressed in skeletal muscle 1.69138
EIF4A1 eukaryotic translation initiation factor 4A1 1.69003
CBR1 carbonyl reductase 1 1.68959
FOXC1 forkhead box C1 1.6813
KLK7 kallikrein-related peptidase 7 1.67768
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 1.67727
ETV3 ets variant 3 1.676
ACTG1 actin gamma 1 1.67443
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1.66992
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 1.66755
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 1.66606
IL1RN interleukin 1 receptor antagonist 1.66501
STRAP serine/threonine kinase receptor associated protein 1.65906
MAP3K5 mitogen-activated protein kinase kinase kinase 5 1.65868
GRB2 growth factor receptor-bound protein 2 1.65298
CAPN2 calpain 2, (m/II) large subunit 1.65192
PRPF31 pre-mRNA processing factor 31 1.6497
TFCP2 transcription factor CP2 1.64875
CBFB core-binding factor, beta subunit 1.64807
TUBB tubulin, beta class I 1.64534
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.64189
TCEAL4 transcription elongation factor A (SII)-like 4 1.63959
CA11 carbonic anhydrase XI 1.63816
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) 1.63728
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 1.63669
GLUD2 glutamate dehydrogenase 2 1.63068
PTMA prothymosin, alpha 1.62587
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.62203
GSTA4 glutathione S-transferase alpha 4 1.62153
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 1.62093
MCM6 minichromosome maintenance complex component 6 1.6183
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 1.61541
LAPTM4B lysosomal protein transmembrane 4 beta 1.61273
TIMP1 TIMP metallopeptidase inhibitor 1 1.60922
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 1.6068
SPINT1 serine peptidase inhibitor, Kunitz type 1 1.60579
TMBIM6 transmembrane BAX inhibitor motif containing 6 1.60417
TCP1 t-complex 1 1.6038
SFPQ splicing factor proline/glutamine-rich 1.60337
CSK c-src tyrosine kinase 1.59953
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 1.59166
ASB1 ankyrin repeat and SOCS box containing 1 1.59102
IFNAR2 interferon (alpha, beta and omega) receptor 2 1.58934
XPC xeroderma pigmentosum, complementation group C 1.58845
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1.58663
DEGS1 delta(4)-desaturase, sphingolipid 1 1.58399
RNF14 ring finger protein 14 1.58213
ARF1 ADP-ribosylation factor 1 1.58129
CELF1 CUGBP, Elav-like family member 1 1.57835
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.57587
WBSCR22 Williams Beuren syndrome chromosome region 22 1.57482
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 1.57393
ANXA5 annexin A5 1.57316
HNRNPK heterogeneous nuclear ribonucleoprotein K 1.56992
HIRA histone cell cycle regulator 1.5699
PRICKLE3 prickle homolog 3 (Drosophila) 1.56835
ACTL6A actin-like 6A 1.56434
AQP3 aquaporin 3 (Gill blood group) 1.56333
GTF2B general transcription factor IIB 1.55424
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 1.55054
FAM32A family with sequence similarity 32, member A 1.54708
FHL2 four and a half LIM domains 2 1.54576
PRPF4 pre-mRNA processing factor 4 1.54457
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.54295
SRSF8 serine/arginine-rich splicing factor 8 1.54097
FADS3 fatty acid desaturase 3 1.53404
SPAG7 sperm associated antigen 7 1.53296
CDC123 cell division cycle 123 1.52621
MGLL monoglyceride lipase 1.52413
TRADD TNFRSF1A-associated via death domain 1.52368
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 1.52054
NBL1 neuroblastoma 1, DAN family BMP antagonist 1.51792
NPTN neuroplastin 1.51706
TMCO1 transmembrane and coiled-coil domains 1 1.51142
SLC25A44 solute carrier family 25, member 44 1.51029
RNPS1 RNA binding protein S1, serine-rich domain 1.50808
SAR1A secretion associated, Ras related GTPase 1A 1.50539
RAN RAN, member RAS oncogene family 1.50462
S100A2 S100 calcium binding protein A2 1.50194
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 1.50012
ITM2B integral membrane protein 2B 1.49847
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 1.49768
PEX7 peroxisomal biogenesis factor 7 1.49656
RPL37A ribosomal protein L37a 1.49444
FBXO28 F-box protein 28 1.49341
RSC1A1 regulatory solute carrier protein, family 1, member 1 1.49285
TUBA1B tubulin, alpha 1b 1.48975
SORD sorbitol dehydrogenase 1.48567
CREB3L1 cAMP responsive element binding protein 3-like 1 1.48545
MTAP methylthioadenosine phosphorylase 1.48387
RAD23A RAD23 homolog A (S. cerevisiae) 1.47988
MAEA macrophage erythroblast attacher 1.47895
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 1.4788
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.47566
SKP1 S-phase kinase-associated protein 1 1.47162
GDI1 GDP dissociation inhibitor 1 1.47033
FTL ferritin, light polypeptide 1.46775
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.46695
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) 1.46645
SDC3 syndecan 3 1.46607
LYRM1 LYR motif containing 1 1.46575
RER1 retention in endoplasmic reticulum sorting receptor 1 1.46543
HDGF hepatoma-derived growth factor 1.46235
TMEM5 transmembrane protein 5 1.46199
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 1.4609
UMPS uridine monophosphate synthetase 1.45982
FOXK2 forkhead box K2 1.45732
CKAP4 cytoskeleton-associated protein 4 1.45662
AGFG2 ArfGAP with FG repeats 2 1.45585
SNRPB2 small nuclear ribonucleoprotein polypeptide B 1.45238
SRPR signal recognition particle receptor (docking protein) 1.45039
SMNDC1 survival motor neuron domain containing 1 1.44911
IST1 increased sodium tolerance 1 homolog (yeast) 1.44714
GALK2 galactokinase 2 1.44649
UBE2D3 ubiquitin-conjugating enzyme E2D 3 1.44582
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 1.44418
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 1.44248
KLK10 kallikrein-related peptidase 10 1.44222
MOGS mannosyl-oligosaccharide glucosidase 1.43854
MED8 mediator complex subunit 8 1.43538
VAT1 vesicle amine transport 1 1.43469
MRPL3 mitochondrial ribosomal protein L3 1.43384
RHOB ras homolog family member B 1.43333
PARN poly(A)-specific ribonuclease 1.4307
SLC31A1 solute carrier family 31 (copper transporter), member 1 1.42982
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 1.4253
ESRRG estrogen-related receptor gamma 1.41565
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.41355
BCL7A B-cell CLL/lymphoma 7A 1.41316
H3F3B H3 histone, family 3B (H3.3B) 1.41189
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 1.40933
KRT13 keratin 13, type I 1.40801

decreased expression

Symbol Name Standardized Value
FKBP15 FK506 binding protein 15, 133kDa -3.6142
FAM193A family with sequence similarity 193, member A -3.31521
RPL10A ribosomal protein L10a -3.31238
PATZ1 POZ (BTB) and AT hook containing zinc finger 1 -3.14079
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -3.13731
TM7SF2 transmembrane 7 superfamily member 2 -3.06958
DCTN3 dynactin 3 (p22) -3.04087
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 -3.02911
CNPPD1 cyclin Pas1/PHO80 domain containing 1 -2.96077
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -2.76734
ADRA2C adrenoceptor alpha 2C -2.70756
TCTA T-cell leukemia translocation altered -2.70178
MLXIP MLX interacting protein -2.6997
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.65562
TP53I3 tumor protein p53 inducible protein 3 -2.64233
NONO non-POU domain containing, octamer-binding -2.63377
STK25 serine/threonine kinase 25 -2.62332
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa -2.56847
RPS9 ribosomal protein S9 -2.56
PCGF2 polycomb group ring finger 2 -2.54157
IQCK IQ motif containing K -2.52209
COX4I1 cytochrome c oxidase subunit IV isoform 1 -2.50685
MCF2L MCF.2 cell line derived transforming sequence-like -2.49529
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.48023
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -2.44453
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -2.43115
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.42039
EEF2 eukaryotic translation elongation factor 2 -2.41222
NUP214 nucleoporin 214kDa -2.41151
SELENBP1 selenium binding protein 1 -2.40503
PARD6A par-6 family cell polarity regulator alpha -2.39967
SOX3 SRY (sex determining region Y)-box 3 -2.38299
TBC1D22A TBC1 domain family, member 22A -2.3296
CFD complement factor D (adipsin) -2.31395
ATXN10 ataxin 10 -2.30444
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like -2.28232
PRDX2 peroxiredoxin 2 -2.27313
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -2.26476
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -2.24795
RPL14 ribosomal protein L14 -2.24324
LIPE lipase, hormone-sensitive -2.23995
GJB1 gap junction protein, beta 1, 32kDa -2.23595
BAG6 BCL2-associated athanogene 6 -2.23533
MRPL40 mitochondrial ribosomal protein L40 -2.22803
ARSE arylsulfatase E (chondrodysplasia punctata 1) -2.22061
ATG9A autophagy related 9A -2.21686
PC pyruvate carboxylase -2.21058
RPL24 ribosomal protein L24 -2.19709
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -2.18399
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -2.17217
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 -2.17078
CLDN14 claudin 14 -2.16209
NPC2 Niemann-Pick disease, type C2 -2.15049
FAAH fatty acid amide hydrolase -2.13413
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.13338
DNAL4 dynein, axonemal, light chain 4 -2.11962
ETHE1 ethylmalonic encephalopathy 1 -2.11905
PFKL phosphofructokinase, liver -2.10843
CSF1 colony stimulating factor 1 (macrophage) -2.10654
GSTM5 glutathione S-transferase mu 5 -2.10452
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.08247
CADM4 cell adhesion molecule 4 -2.07334
RPS15A ribosomal protein S15a -2.06966
PRPF8 pre-mRNA processing factor 8 -2.06572
DHCR24 24-dehydrocholesterol reductase -2.05662
IVNS1ABP influenza virus NS1A binding protein -2.04936
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -2.04461
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -2.0384
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.03654
RNF187 ring finger protein 187 -2.03038
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 -2.0179
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -2.00335
NCOR2 nuclear receptor corepressor 2 -2.00024
OXA1L oxidase (cytochrome c) assembly 1-like -1.9954
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -1.99434
RPS6 ribosomal protein S6 -1.99088
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -1.98366
RPL3 ribosomal protein L3 -1.98159
EIF4B eukaryotic translation initiation factor 4B -1.98146
CKB creatine kinase, brain -1.97993
PFDN5 prefoldin subunit 5 -1.97744
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -1.97001
AHNAK AHNAK nucleoprotein -1.9688
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 -1.96538
TNNT1 troponin T type 1 (skeletal, slow) -1.96327
MEF2D myocyte enhancer factor 2D -1.96206
GLG1 golgi glycoprotein 1 -1.95417
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -1.94968
DARS aspartyl-tRNA synthetase -1.94831
ADCY2 adenylate cyclase 2 (brain) -1.94337
TBCD tubulin folding cofactor D -1.93387
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -1.93216
POFUT2 protein O-fucosyltransferase 2 -1.92989
RAB13 RAB13, member RAS oncogene family -1.92845
BIN1 bridging integrator 1 -1.9196
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -1.91909
TBCB tubulin folding cofactor B -1.91896
LTA4H leukotriene A4 hydrolase -1.91325
FLOT2 flotillin 2 -1.90906
SBSPON somatomedin B and thrombospondin, type 1 domain containing -1.90338
RPS5 ribosomal protein S5 -1.89886
GCAT glycine C-acetyltransferase -1.89823
CCT7 chaperonin containing TCP1, subunit 7 (eta) -1.89401
MOCS1 molybdenum cofactor synthesis 1 -1.88733
FDXR ferredoxin reductase -1.87794
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -1.87759
AP1G2 adaptor-related protein complex 1, gamma 2 subunit -1.87373
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -1.86457
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -1.85617
PCSK6 proprotein convertase subtilisin/kexin type 6 -1.84824
ESRRA estrogen-related receptor alpha -1.8422
MMP11 matrix metallopeptidase 11 -1.84197
TRIM23 tripartite motif containing 23 -1.84132
NUMB numb homolog (Drosophila) -1.83646
ANXA6 annexin A6 -1.83566
CAPG capping protein (actin filament), gelsolin-like -1.83119
ZC3H4 zinc finger CCCH-type containing 4 -1.82831
DNM1 dynamin 1 -1.82729
ALDOC aldolase C, fructose-bisphosphate -1.82082
GCHFR GTP cyclohydrolase I feedback regulator -1.81681
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -1.81572
LPIN1 lipin 1 -1.8119
HIP1R huntingtin interacting protein 1 related -1.80981
UPK1A uroplakin 1A -1.80965
SIK3 SIK family kinase 3 -1.80678
MYO9B myosin IXB -1.80656
RPL35 ribosomal protein L35 -1.80102
RSL1D1 ribosomal L1 domain containing 1 -1.80014
JAG2 jagged 2 -1.79451
ZNHIT3 zinc finger, HIT-type containing 3 -1.78599
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -1.78441
TSC2 tuberous sclerosis 2 -1.78337
CAMP cathelicidin antimicrobial peptide -1.77747
SETDB1 SET domain, bifurcated 1 -1.77313
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria -1.77185
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) -1.76915
ACP1 acid phosphatase 1, soluble -1.769
TADA3 transcriptional adaptor 3 -1.76812
MYOF myoferlin -1.76302
MTMR9 myotubularin related protein 9 -1.76189
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -1.76133
ELF2 E74-like factor 2 (ets domain transcription factor) -1.75755
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.75721
FOLR2 folate receptor 2 (fetal) -1.75066
ZMYM3 zinc finger, MYM-type 3 -1.74953
DNPEP aspartyl aminopeptidase -1.7456
UQCRH ubiquinol-cytochrome c reductase hinge protein -1.74005
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 -1.73559
FAM107A family with sequence similarity 107, member A -1.73539
KAZN kazrin, periplakin interacting protein -1.73498
TNNC1 troponin C type 1 (slow) -1.73321
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -1.7285
TUFM Tu translation elongation factor, mitochondrial -1.71731
CSTB cystatin B (stefin B) -1.71104
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -1.70285
PEX6 peroxisomal biogenesis factor 6 -1.7001
STX3 syntaxin 3 -1.69683
KAT6B K(lysine) acetyltransferase 6B -1.6965
EPHB2 EPH receptor B2 -1.69611
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -1.69523
TWF2 twinfilin actin binding protein 2 -1.69508
ACTN1 actinin, alpha 1 -1.69412
MPST mercaptopyruvate sulfurtransferase -1.6937
AP3D1 adaptor-related protein complex 3, delta 1 subunit -1.69359
MT1G metallothionein 1G -1.69003
CCT4 chaperonin containing TCP1, subunit 4 (delta) -1.68974
RGS3 regulator of G-protein signaling 3 -1.68818
MPI mannose phosphate isomerase -1.68015
MYO1D myosin ID -1.67657
STX8 syntaxin 8 -1.67297
ILVBL ilvB (bacterial acetolactate synthase)-like -1.67279
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa -1.66823
CHD3 chromodomain helicase DNA binding protein 3 -1.66618
C11ORF80 chromosome 11 open reading frame 80 -1.66105
CUL1 cullin 1 -1.65849
WDR18 WD repeat domain 18 -1.65698
CCDC6 coiled-coil domain containing 6 -1.65594
EFNA1 ephrin-A1 -1.65339
BUD31 BUD31 homolog (S. cerevisiae) -1.65226
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -1.649
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -1.6476
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -1.63713
VARS valyl-tRNA synthetase -1.63533
OVOL2 ovo-like zinc finger 2 -1.63452
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 -1.63441
NACA nascent polypeptide-associated complex alpha subunit -1.63324
SORBS3 sorbin and SH3 domain containing 3 -1.63255
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -1.63235
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -1.63171
DKK4 dickkopf WNT signaling pathway inhibitor 4 -1.63022
EIF3E eukaryotic translation initiation factor 3, subunit E -1.62784
CRHR2 corticotropin releasing hormone receptor 2 -1.62115
SMG5 SMG5 nonsense mediated mRNA decay factor -1.61914
UQCRC1 ubiquinol-cytochrome c reductase core protein I -1.61357
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -1.61322
LRPPRC leucine-rich pentatricopeptide repeat containing -1.61249
SEC16A SEC16 homolog A (S. cerevisiae) -1.60943
GMPR guanosine monophosphate reductase -1.60735
METAP1 methionyl aminopeptidase 1 -1.6043
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -1.60091
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d -1.59899
SUN2 Sad1 and UNC84 domain containing 2 -1.59867
MT1F metallothionein 1F -1.59766
GSTO1 glutathione S-transferase omega 1 -1.59641
DNM2 dynamin 2 -1.59604
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 -1.59563
NME2 NME/NM23 nucleoside diphosphate kinase 2 -1.59135
TEAD4 TEA domain family member 4 -1.58909
KDM1A lysine (K)-specific demethylase 1A -1.58679
NAGA N-acetylgalactosaminidase, alpha- -1.58435
CIZ1 CDKN1A interacting zinc finger protein 1 -1.58396
TECR trans-2,3-enoyl-CoA reductase -1.58375
MED20 mediator complex subunit 20 -1.58326
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -1.57781
CLSTN1 calsyntenin 1 -1.57277
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 -1.57247
TST thiosulfate sulfurtransferase (rhodanese) -1.57198
SMG7 SMG7 nonsense mediated mRNA decay factor -1.5575
HDAC1 histone deacetylase 1 -1.55708
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 -1.55605
JAK1 Janus kinase 1 -1.54924
TRIO trio Rho guanine nucleotide exchange factor -1.54624
COQ9 coenzyme Q9 -1.54382
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -1.54077
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -1.53977
DOLPP1 dolichyldiphosphatase 1 -1.53884
MMP24 matrix metallopeptidase 24 (membrane-inserted) -1.53791
PODXL podocalyxin-like -1.53135
MAN2B2 mannosidase, alpha, class 2B, member 2 -1.52902
FOLR1 folate receptor 1 (adult) -1.52855
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -1.52654
TYRO3 TYRO3 protein tyrosine kinase -1.52438
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -1.52323
GYS1 glycogen synthase 1 (muscle) -1.5224
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -1.5192
CGRRF1 cell growth regulator with ring finger domain 1 -1.5155
RPL13 ribosomal protein L13 -1.51514
UVRAG UV radiation resistance associated -1.51512
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 -1.51305
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -1.51254
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -1.51175
GRP gastrin-releasing peptide -1.51028
GRHPR glyoxylate reductase/hydroxypyruvate reductase -1.50578
PREP prolyl endopeptidase -1.49377
PSD4 pleckstrin and Sec7 domain containing 4 -1.49275
MVP major vault protein -1.4923
PYGL phosphorylase, glycogen, liver -1.49193
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) -1.48143
ZNF230 zinc finger protein 230 -1.47673
UPK2 uroplakin 2 -1.47286
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -1.47271
ISLR immunoglobulin superfamily containing leucine-rich repeat -1.47243
LMF2 lipase maturation factor 2 -1.47073
MRPS27 mitochondrial ribosomal protein S27 -1.47026
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -1.46853
DCAF11 DDB1 and CUL4 associated factor 11 -1.46351
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -1.46294
HSF1 heat shock transcription factor 1 -1.46178
PPIE peptidylprolyl isomerase E (cyclophilin E) -1.46125
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 -1.46092
AFG3L2 AFG3-like AAA ATPase 2 -1.45478
CRIP1 cysteine-rich protein 1 (intestinal) -1.45282
PLD2 phospholipase D2 -1.45103
DPYSL4 dihydropyrimidinase-like 4 -1.45071
MGST3 microsomal glutathione S-transferase 3 -1.44846
SEC14L2 SEC14-like 2 (S. cerevisiae) -1.44716
INTS1 integrator complex subunit 1 -1.44617
PTPRK protein tyrosine phosphatase, receptor type, K -1.44378
RPS21 ribosomal protein S21 -1.44275
FANCC Fanconi anemia, complementation group C -1.43819
MAN2A2 mannosidase, alpha, class 2A, member 2 -1.43655
MT1H metallothionein 1H -1.43423
PARP3 poly (ADP-ribose) polymerase family, member 3 -1.43371
SGSM2 small G protein signaling modulator 2 -1.43289
OLFML2A olfactomedin-like 2A -1.43248
NEU1 sialidase 1 (lysosomal sialidase) -1.43207
TCF25 transcription factor 25 (basic helix-loop-helix) -1.43147
RPL32 ribosomal protein L32 -1.4293
ZFYVE26 zinc finger, FYVE domain containing 26 -1.42907
IKZF1 IKAROS family zinc finger 1 (Ikaros) -1.42854
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -1.42821
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 -1.42694
SGSM3 small G protein signaling modulator 3 -1.4263
RPS15 ribosomal protein S15 -1.42511
PHGDH phosphoglycerate dehydrogenase -1.42375
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -1.42167
RECQL4 RecQ protein-like 4 -1.42008
WNT4 wingless-type MMTV integration site family, member 4 -1.41797
UQCRB ubiquinol-cytochrome c reductase binding protein -1.41666
PPP6C protein phosphatase 6, catalytic subunit -1.41532
MLN motilin -1.41494
SEC14L1 SEC14-like 1 (S. cerevisiae) -1.41168
IFITM2 interferon induced transmembrane protein 2 -1.41101
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -1.41055
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -1.40786
INHA inhibin, alpha -1.40448
SHROOM2 shroom family member 2 -1.40391
MGMT O-6-methylguanine-DNA methyltransferase -1.40233
IGBP1 immunoglobulin (CD79A) binding protein 1 -1.40054
TELO2 telomere maintenance 2 -1.39893