Prostatic Intraepithelial Neoplasia Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A neoplastic proliferation of the epithelial cells that line the acini and the ducts of the prostate gland. The neoplastic epithelial cells are confined within the acini and the ducts and they do not invade the surrounding prostatic stroma. Morphologically, it is classified as low or high grade.|noninvasive prostate duct lesions that affect smaller caliber ducts (Experimental Factor Ontology, EFO_0002621)
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Genes

3 genes associated with the Prostatic Intraepithelial Neoplasia phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
NOS3 nitric oxide synthase 3 (endothelial cell)
PTEN phosphatase and tensin homolog
TP53 tumor protein p53