Prostatic Intraepithelial Neoplasia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A neoplastic proliferation of the epithelial cells that line the acini and the ducts of the prostate gland. The neoplastic epithelial cells are confined within the acini and the ducts and they do not invade the surrounding prostatic stroma. Morphologically, it is classified as low or high grade.|noninvasive prostate duct lesions that affect smaller caliber ducts (Experimental Factor Ontology, EFO_0002621)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D019048
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Genes

40 genes/proteins associated with the disease Prostatic Intraepithelial Neoplasia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.88009
GSTP1 glutathione S-transferase pi 1 2.88009
PTEN phosphatase and tensin homolog 2.88009
MT2A metallothionein 2A 2.88009
ESR2 estrogen receptor 2 (ER beta) 2.88009
ESR1 estrogen receptor 1 2.88009
DNMT1 DNA (cytosine-5-)-methyltransferase 1 2.88009
AR androgen receptor 2.88009
TOP2B topoisomerase (DNA) II beta 180kDa 2.88009
TP63 tumor protein p63 2.88009
PIM1 Pim-1 proto-oncogene, serine/threonine kinase 2.88009
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 2.88009
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.30635
INSR insulin receptor 1.28395
CAB39L calcium binding protein 39-like 1.19574
TFCP2L1 transcription factor CP2-like 1 1.16035
CD81 CD81 molecule 1.11741
S100A9 S100 calcium binding protein A9 1.09047
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.08549
LIN7A lin-7 homolog A (C. elegans) 1.0784
CA2 carbonic anhydrase II 1.07482
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 1.07199
GPX2 glutathione peroxidase 2 1.07199
RHOA ras homolog family member A 1.07022
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 1.06844
GH1 growth hormone 1 1.06008
FOXA1 forkhead box A1 1.04611
LCN2 lipocalin 2 1.03159
LUM lumican 1.03122
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 1.02971
ACTG2 actin, gamma 2, smooth muscle, enteric 1.02933
FBXO5 F-box protein 5 1.02858
KRT5 keratin 5, type II 1.02596
MCAM melanoma cell adhesion molecule 1.02559
IGF1R insulin-like growth factor 1 receptor 1.02151
COL5A1 collagen, type V, alpha 1 1.01739
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.01249
TEKT1 tektin 1 1.01212
CPXM2 carboxypeptidase X (M14 family), member 2 1.01212
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) 1.01212