Pelvic Organ Prolapse Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Abnormal descent of a pelvic organ resulting in the protrusion of the organ beyond its normal anatomical confines. (Experimental Factor Ontology, EFO_0004710)
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Genes

12 genes associated with the Pelvic Organ Prolapse phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
LAMC1 laminin, gamma 1 (formerly LAMB2)
MMP1 matrix metallopeptidase 1
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
PARP1 poly (ADP-ribose) polymerase 1
ZFAT zinc finger and AT hook domain containing