Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUU-01A-11R-A37L-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Pancreatic adenocarcinoma_PAAD (The Cancer Genome Atlas)
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355 genes with high or low expression in Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUU-01A-11R-A37L-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ABCC13 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene
ABHD3 abhydrolase domain containing 3
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACAA1 acetyl-CoA acyltransferase 1
ACOT11 acyl-CoA thioesterase 11
ACRV1 acrosomal vesicle protein 1
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSF2 acyl-CoA synthetase family member 2
ACTN4 actinin, alpha 4
ADAM8 ADAM metallopeptidase domain 8
ADAM9 ADAM metallopeptidase domain 9
ADCK4 aarF domain containing kinase 4
ADGRD2 adhesion G protein-coupled receptor D2
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
ALAS1 5'-aminolevulinate synthase 1
ALOX5 arachidonate 5-lipoxygenase
ANK1 ankyrin 1, erythrocytic
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARHGEF35 Rho guanine nucleotide exchange factor (GEF) 35
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARRB1 arrestin, beta 1
ASCC1 activating signal cointegrator 1 complex subunit 1
ASL argininosuccinate lyase
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP13A5 ATPase type 13A5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAK1 BCL2-antagonist/killer 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCORL1 BCL6 corepressor-like 1
BECN1 beclin 1, autophagy related
BIN1 bridging integrator 1
BLVRB biliverdin reductase B
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
BTNL8 butyrophilin-like 8
C11ORF86 chromosome 11 open reading frame 86
C15ORF39 chromosome 15 open reading frame 39
C1D C1D nuclear receptor corepressor
C1ORF100 chromosome 1 open reading frame 100
C20ORF24 chromosome 20 open reading frame 24
C6ORF132 chromosome 6 open reading frame 132
C8ORF4 chromosome 8 open reading frame 4
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CALM2 calmodulin 2 (phosphorylase kinase, delta)
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CAPG capping protein (actin filament), gelsolin-like
CARD18 caspase recruitment domain family, member 18
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CEACAM22P carcinoembryonic antigen-related cell adhesion molecule 22, pseudogene
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CFDP1 craniofacial development protein 1
CIB1 calcium and integrin binding 1 (calmyrin)
CIDEC cell death-inducing DFFA-like effector c
CKMT1A creatine kinase, mitochondrial 1A
CLDN9 claudin 9
CLLU1OS chronic lymphocytic leukemia up-regulated 1 opposite strand
CLTB clathrin, light chain B
CMC1 C-x(9)-C motif containing 1
CMPK2 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
CMTM6 CKLF-like MARVEL transmembrane domain containing 6
CNGA1 cyclic nucleotide gated channel alpha 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COG4 component of oligomeric golgi complex 4
CPA6 carboxypeptidase A6
CREG2 cellular repressor of E1A-stimulated genes 2
CRYAA crystallin, alpha A
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18
DAPK2 death-associated protein kinase 2
DBNL drebrin-like
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DEC1 deleted in esophageal cancer 1
DHRS1 dehydrogenase/reductase (SDR family) member 1
DLX6-AS1 DLX6 antisense RNA 1
DMWD dystrophia myotonica, WD repeat containing
DNMBP dynamin binding protein
DNMBP-AS1 DNMBP antisense RNA 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNTT DNA nucleotidylexotransferase
DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1
DOK4 docking protein 4
EAF1 ELL associated factor 1
ECE1 endothelin converting enzyme 1
ECH1 enoyl CoA hydratase 1, peroxisomal
EGLN2 egl-9 family hypoxia-inducible factor 2
EHD4 EH-domain containing 4
EIF1B eukaryotic translation initiation factor 1B
ELF4 E74-like factor 4 (ets domain transcription factor)
ELOVL6 ELOVL fatty acid elongase 6
EML2 echinoderm microtubule associated protein like 2
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EPHA1 EPH receptor A1
EPSTI1 epithelial stromal interaction 1 (breast)
ETFA electron-transfer-flavoprotein, alpha polypeptide
FA2H fatty acid 2-hydroxylase
FABP3 fatty acid binding protein 3, muscle and heart
FAM138E family with sequence similarity 138, member E
FAM224B family with sequence similarity 224, member B (non-protein coding)
FAM90A7P putative protein FAM90A7
FAM98C family with sequence similarity 98, member C
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL19 F-box and leucine-rich repeat protein 19
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXC2 forkhead box C2
FSCB fibrous sheath CABYR binding protein
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli)
GAL3ST1 galactose-3-O-sulfotransferase 1
GALC galactosylceramidase
GANC glucosidase, alpha; neutral C
GBP3 guanylate binding protein 3
GCKR glucokinase (hexokinase 4) regulator
GCOM1 GRINL1A complex locus 1
GDPGP1 GDP-D-glucose phosphorylase 1
GEMIN7 gem (nuclear organelle) associated protein 7
GHRHR growth hormone releasing hormone receptor
GJB4 gap junction protein, beta 4, 30.3kDa
GLB1 galactosidase, beta 1
GLRA4 glycine receptor, alpha 4
GOLGA7 golgin A7
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial
GPC5 glypican 5
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPN2 GPN-loop GTPase 2
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GUCA1B guanylate cyclase activator 1B (retina)
GUCY2GP guanylate cyclase 2G, pseudogene
HAL histidine ammonia-lyase
HELZ2 helicase with zinc finger 2, transcriptional coactivator
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HHLA2 HERV-H LTR-associating 2
HKDC1 hexokinase domain containing 1
HLA-J major histocompatibility complex, class I, J (pseudogene)
HNRNPL heterogeneous nuclear ribonucleoprotein L
HOXA1 homeobox A1
HOXA11-AS HOXA11 antisense RNA
HRH2 histamine receptor H2
HRH4 histamine receptor H4
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSFY2 heat shock transcription factor, Y linked 2
HSPB9 heat shock protein, alpha-crystallin-related, B9
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
HYAL4 hyaluronoglucosaminidase 4
IFI27 interferon, alpha-inducible protein 27
IFI35 interferon-induced protein 35
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGSF5 immunoglobulin superfamily, member 5
IL17RE interleukin 17 receptor E
INSC inscuteable homolog (Drosophila)
IRAK2 interleukin-1 receptor-associated kinase 2
ITFG3 integrin alpha FG-GAP repeat containing 3
ITPKA inositol-trisphosphate 3-kinase A
ITPKC inositol-trisphosphate 3-kinase C
IWS1 IWS1 homolog (S. cerevisiae)
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9
KCNK6 potassium channel, two pore domain subfamily K, member 6
KCTD5 potassium channel tetramerization domain containing 5
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KLHL41 kelch-like family member 41
LCE3A late cornified envelope 3A
LGALS4 lectin, galactoside-binding, soluble, 4
LINC00305 long intergenic non-protein coding RNA 305
LINC00467 long intergenic non-protein coding RNA 467
LINC01555 long intergenic non-protein coding RNA 1555
LOC100128573 uncharacterized LOC100128573
LOC644669 ankyrin repeat domain 30B pseudogene
LPIN1 lipin 1
LRRC42 leucine rich repeat containing 42
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MALL mal, T-cell differentiation protein-like
MAPK3 mitogen-activated protein kinase 3
MED28 mediator complex subunit 28
MESDC1 mesoderm development candidate 1
MGST2 microsomal glutathione S-transferase 2
MLKL mixed lineage kinase domain-like
MRPL42P5 mitochondrial ribosomal protein L42 pseudogene 5
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MTMR14 myotubularin related protein 14
MYD88 myeloid differentiation primary response 88
MYL10 myosin, light chain 10, regulatory
MYO7B myosin VIIB
MYOM1 myomesin 1
MYPN myopalladin
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NET1 neuroepithelial cell transforming 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NGLY1 N-glycanase 1
NGRN neugrin, neurite outgrowth associated
NMI N-myc (and STAT) interactor
NPAS1 neuronal PAS domain protein 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRG3 neuregulin 3
NSUN7 NOP2/Sun domain family, member 7
NUTM2F NUT family member 2F
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive
OPTN optineurin
OR1L3 olfactory receptor, family 1, subfamily L, member 3
OR2AE1 olfactory receptor, family 2, subfamily AE, member 1
OR4F6 olfactory receptor, family 4, subfamily F, member 6
OR52B2 olfactory receptor, family 52, subfamily B, member 2
OR52L1 olfactory receptor, family 52, subfamily L, member 1
OR56A5 olfactory receptor, family 56, subfamily A, member 5
OR6B2 olfactory receptor, family 6, subfamily B, member 2
OSGEP O-sialoglycoprotein endopeptidase
OVOL1 ovo-like zinc finger 1
OXSR1 oxidative stress responsive 1
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PCDHB3 protocadherin beta 3
PCDHGB1 protocadherin gamma subfamily B, 1
PDCD6IP programmed cell death 6 interacting protein
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDZD7 PDZ domain containing 7
PHLDA2 pleckstrin homology-like domain, family A, member 2
PKD1L1 polycystic kidney disease 1 like 1
PLA2G10 phospholipase A2, group X
PLA2R1 phospholipase A2 receptor 1, 180kDa
PLBD1 phospholipase B domain containing 1
PLCD3 phospholipase C, delta 3
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEK2 pleckstrin 2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
PLSCR1 phospholipid scramblase 1
PNP purine nucleoside phosphorylase
PPARG peroxisome proliferator-activated receptor gamma
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP5C protein phosphatase 5, catalytic subunit
PRDM8 PR domain containing 8
PRKD2 protein kinase D2
PRO0611 PRO0611 protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PRSS22 protease, serine, 22
PSMD8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
QPRT quinolinate phosphoribosyltransferase
RAB11A RAB11A, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RBP3 retinol binding protein 3, interstitial
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RHPN2 rhophilin, Rho GTPase binding protein 2
RINL Ras and Rab interactor-like
RNF149 ring finger protein 149
RNF5P1 ring finger protein 5, E3 ubiquitin protein ligase pseudogene 1
RTP2 receptor (chemosensory) transporter protein 2
SAE1 SUMO1 activating enzyme subunit 1
SAMD7 sterile alpha motif domain containing 7
SCCPDH saccharopine dehydrogenase (putative)
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SEPHS2 selenophosphate synthetase 2
SERINC2 serine incorporator 2
SERTAD1 SERTA domain containing 1
SERTAD3 SERTA domain containing 3
SFT2D1 SFT2 domain containing 1
SGK2 serum/glucocorticoid regulated kinase 2
SH2D3A SH2 domain containing 3A
SHH sonic hedgehog
SHKBP1 SH3KBP1 binding protein 1
SIRT2 sirtuin 2
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC16A4 solute carrier family 16, member 4
SLC22A18 solute carrier family 22, member 18
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12
SMAD3 SMAD family member 3
SMNDC1 survival motor neuron domain containing 1
SNORA56 small nucleolar RNA, H/ACA box 56
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPIRE2 spire-type actin nucleation factor 2
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
STAMBP STAM binding protein
STAMBPL1 STAM binding protein-like 1
STRN3 striatin, calmodulin binding protein 3
STRN4 striatin, calmodulin binding protein 4
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TACC1 transforming, acidic coiled-coil containing protein 1
TAS2R60 taste receptor, type 2, member 60
TBC1D10B TBC1 domain family, member 10B
TBC1D3F TBC1 domain family, member 3F
TCP10 t-complex 10
TCP10L2 t-complex 10-like 2
TECTB tectorin beta
TEX33 testis expressed 33
TFF1 trefoil factor 1
TLDC2 TBC/LysM-associated domain containing 2
TM2D2 TM2 domain containing 2
TMEM105 transmembrane protein 105
TMEM229B transmembrane protein 229B
TMEM30B transmembrane protein 30B
TMEM41B transmembrane protein 41B
TMSB4Y thymosin beta 4, Y-linked
TP53I11 tumor protein p53 inducible protein 11
TP53INP2 tumor protein p53 inducible nuclear protein 2
TRIP4 thyroid hormone receptor interactor 4
TRNP1 TMF1-regulated nuclear protein 1
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TSC22D2 TSC22 domain family, member 2
TSPAN15 tetraspanin 15
TSPAN3 tetraspanin 3
TTLL4 tubulin tyrosine ligase-like family member 4
TTTY14 testis-specific transcript, Y-linked 14 (non-protein coding)
TTTY18 testis-specific transcript, Y-linked 18 (non-protein coding)
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UPK1B uroplakin 1B
VILL villin-like
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
VTI1B vesicle transport through interaction with t-SNAREs 1B
VWA5B1 von Willebrand factor A domain containing 5B1
XAGE3 X antigen family, member 3
XKRY2 XK, Kell blood group complex subunit-related, Y-linked 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZDHHC6 zinc finger, DHHC-type containing 6
ZFAND6 zinc finger, AN1-type domain 6
ZFP57 ZFP57 zinc finger protein
ZFYVE19 zinc finger, FYVE domain containing 19
ZNF341 zinc finger protein 341
ZNF488 zinc finger protein 488
ZNF846 zinc finger protein 846
ZSCAN4 zinc finger and SCAN domain containing 4

low expression

Symbol Name
NOL8 nucleolar protein 8
PGBD3 piggyBac transposable element derived 3
SHPK sedoheptulokinase
SS18 synovial sarcoma translocation, chromosome 18
TBC1D20 TBC1 domain family, member 20
TMEM69 transmembrane protein 69
TPGS2 tubulin polyglutamylase complex subunit 2
TRIM32 tripartite motif containing 32
TTF1 transcription termination factor, RNA polymerase I
ZNF584 zinc finger protein 584