POLE3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description polymerase (DNA directed), epsilon 3, accessory subunit|POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004] (NCBI Entrez Gene Database, 54107)
External Link http://www.ncbi.nlm.nih.gov/gene/54107
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Genes

68 interacting proteins for POLE3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AHCY adenosylhomocysteinase
AKAP9 A kinase (PRKA) anchor protein 9
ALMS1 Alstrom syndrome protein 1
ANAPC1 anaphase promoting complex subunit 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA6 annexin A6
APP amyloid beta (A4) precursor protein
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARRB2 arrestin, beta 2
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BICD2 bicaudal D homolog 2 (Drosophila)
CARM1 coactivator-associated arginine methyltransferase 1
CHRAC1 chromatin accessibility complex 1
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa
DIAPH1 diaphanous-related formin 1
DOHH deoxyhypusine hydroxylase/monooxygenase
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha)
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3C eukaryotic translation initiation factor 3, subunit C
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF3E eukaryotic translation initiation factor 3, subunit E
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF3H eukaryotic translation initiation factor 3, subunit H
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF3M eukaryotic translation initiation factor 3, subunit M
EML3 echinoderm microtubule associated protein like 3
EPPK1 epiplakin 1
FKBP4 FK506 binding protein 4, 59kDa
FLAD1 flavin adenine dinucleotide synthetase 1
FLCN folliculin
FNIP1 folliculin interacting protein 1
FOXC1 forkhead box C1
GAK cyclin G associated kinase
GOLGA1 golgin A1
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HNF4A hepatocyte nuclear factor 4, alpha
IFT122 intraflagellar transport 122
LIMD1 LIM domains containing 1
MCL1 myeloid cell leukemia 1
MCM4 minichromosome maintenance complex component 4
MSH2 mutS homolog 2
NANS N-acetylneuraminic acid synthase
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFU1 NFU1 iron-sulfur cluster scaffold
OSBPL3 oxysterol binding protein-like 3
OSBPL6 oxysterol binding protein-like 6
PARP4 poly (ADP-ribose) polymerase family, member 4
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit
PUM2 pumilio RNA-binding family member 2
RAD17 RAD17 homolog (S. pombe)
SARS seryl-tRNA synthetase
SF3A3 splicing factor 3a, subunit 3, 60kDa
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMG6 SMG6 nonsense mediated mRNA decay factor
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
SUMO2 small ubiquitin-like modifier 2
TRPS1 trichorhinophalangeal syndrome I
UBC ubiquitin C
UBR4 ubiquitin protein ligase E3 component n-recognin 4
VBP1 von Hippel-Lindau binding protein 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YEATS2 YEATS domain containing 2