PK-45P Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description A immortal human cell line cell that has the characteristics: Human cell line derived from pancreatic carcinoma. RCB1973 is derived from the same patient. TKG0493(Deposited from Tohoku Univ.). (Cell Line Ontology, CLO_0050107)
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Genes

160 genes mutated in the PK-45P cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ACOX3 acyl-CoA oxidase 3, pristanoyl
ADCK1 aarF domain containing kinase 1
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANKRD16 ankyrin repeat domain 16
ANKRD26 ankyrin repeat domain 26
ANKRD52 ankyrin repeat domain 52
BOP1 block of proliferation 1
C19ORF57 chromosome 19 open reading frame 57
CABLES2 Cdk5 and Abl enzyme substrate 2
CADPS2 Ca++-dependent secretion activator 2
CARS cysteinyl-tRNA synthetase
CCDC154 coiled-coil domain containing 154
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEP152 centrosomal protein 152kDa
CHD6 chromodomain helicase DNA binding protein 6
CIC capicua transcriptional repressor
CLDN3 claudin 3
CRYBG3 beta-gamma crystallin domain containing 3
CTC1 CTS telomere maintenance complex component 1
CUL4A cullin 4A
CUL9 cullin 9
CYB5R1 cytochrome b5 reductase 1
DAPK1 death-associated protein kinase 1
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DMXL2 Dmx-like 2
DST dystonin
DYX1C1 dyslexia susceptibility 1 candidate 1
EED embryonic ectoderm development
EFR3A EFR3 homolog A (S. cerevisiae)
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
ETAA1 Ewing tumor-associated antigen 1
FAM161B family with sequence similarity 161, member B
FAM83H family with sequence similarity 83, member H
FBXO30 F-box protein 30
FEN1 flap structure-specific endonuclease 1
FPGT fucose-1-phosphate guanylyltransferase
FRAS1 Fraser extracellular matrix complex subunit 1
GALK1 galactokinase 1
GBAS glioblastoma amplified sequence
GBP3 guanylate binding protein 3
GOLGB1 golgin B1
GOLIM4 golgi integral membrane protein 4
GRIP1 glutamate receptor interacting protein 1
GRWD1 glutamate-rich WD repeat containing 1
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa
HDAC4 histone deacetylase 4
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HSBP1 heat shock factor binding protein 1
HYLS1 hydrolethalus syndrome 1
IGSF9B immunoglobulin superfamily, member 9B
INADL InaD-like (Drosophila)
INSRR insulin receptor-related receptor
ITGB6 integrin, beta 6
ITSN1 intersectin 1 (SH3 domain protein)
JDP2 Jun dimerization protein 2
JMJD8 jumonji domain containing 8
JUP junction plakoglobin
KAT6A K(lysine) acetyltransferase 6A
KCTD1 potassium channel tetramerization domain containing 1
KIF1BP KIF1 binding protein
KIF20A kinesin family member 20A
KIF21B kinesin family member 21B
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT13 keratin 13, type I
LAMC2 laminin, gamma 2
LAS1L LAS1-like (S. cerevisiae)
LMBRD2 LMBR1 domain containing 2
LRRC29 leucine rich repeat containing 29
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LYPLA1 lysophospholipase I
LYST lysosomal trafficking regulator
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MCAM melanoma cell adhesion molecule
MFSD1 major facilitator superfamily domain containing 1
MLH3 mutL homolog 3
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
MPPE1 metallophosphoesterase 1
MTBP MDM2 binding protein
NBEAL2 neurobeachin-like 2
NCOR2 nuclear receptor corepressor 2
NME7 NME/NM23 family member 7
NRG4 neuregulin 4
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NSUN6 NOP2/Sun domain family, member 6
ODF2L outer dense fiber of sperm tails 2-like
OSBPL6 oxysterol binding protein-like 6
OXR1 oxidation resistance 1
PCNXL2 pecanex-like 2 (Drosophila)
PCSK9 proprotein convertase subtilisin/kexin type 9
PEX13 peroxisomal biogenesis factor 13
PHIP pleckstrin homology domain interacting protein
PLCE1 phospholipase C, epsilon 1
PLEC plectin
PLXNB2 plexin B2
PPAP2C phosphatidic acid phosphatase type 2C
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PPT1 palmitoyl-protein thioesterase 1
PROB1 proline-rich basic protein 1
PRSS8 protease, serine, 8
PTX3 pentraxin 3, long
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RABGAP1L RAB GTPase activating protein 1-like
RAI14 retinoic acid induced 14
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RBL1 retinoblastoma-like 1
RC3H1 ring finger and CCCH-type domains 1
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
REEP5 receptor accessory protein 5
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
RNF145 ring finger protein 145
RP1L1 retinitis pigmentosa 1-like 1
SART3 squamous cell carcinoma antigen recognized by T cells 3
SERINC5 serine incorporator 5
SFPQ splicing factor proline/glutamine-rich
SIX5 SIX homeobox 5
SLC34A3 solute carrier family 34 (type II sodium/phosphate cotransporter), member 3
SLC38A10 solute carrier family 38, member 10
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SMAP2 small ArfGAP2
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STAMBPL1 STAM binding protein-like 1
SUMF1 sulfatase modifying factor 1
SYF2 SYF2 pre-mRNA-splicing factor
TBC1D16 TBC1 domain family, member 16
TBP TATA box binding protein
TFRC transferrin receptor
TIGD1 tigger transposable element derived 1
TIGD5 tigger transposable element derived 5
TLK2 tousled-like kinase 2
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSC2 tuberous sclerosis 2
TTLL4 tubulin tyrosine ligase-like family member 4
TUFT1 tuftelin 1
UBE4B ubiquitination factor E4B
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UGP2 UDP-glucose pyrophosphorylase 2
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP53 ubiquitin specific peptidase 53
VCAN versican
WAC WW domain containing adaptor with coiled-coil
WDFY3 WD repeat and FYVE domain containing 3
WDR36 WD repeat domain 36
ZFHX3 zinc finger homeobox 3
ZFPM1 zinc finger protein, FOG family member 1
ZIK1 zinc finger protein interacting with K protein 1
ZMYM5 zinc finger, MYM-type 5
ZNF112 zinc finger protein 112
ZNF180 zinc finger protein 180
ZNF579 zinc finger protein 579
ZNF598 zinc finger protein 598
ZNF616 zinc finger protein 616
ZNF786 zinc finger protein 786
ZNHIT2 zinc finger, HIT-type containing 2
ZXDB zinc finger, X-linked, duplicated B