PK-45H Gene Set

Dataset Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles
Category genomics
Type cell line
Description A immortal human cell line cell that has the characteristics: Human pancreatic carcinoma cell line, the same patient as RCB2141. TKG0491(Deposited from Tohoku Univ.). (Cell Line Ontology, CLO_0050106)
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135 genes mutated in the PK-45H cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

Symbol Name
ACACB acetyl-CoA carboxylase beta
ACSF3 acyl-CoA synthetase family member 3
ADGRL2 adhesion G protein-coupled receptor L2
AHDC1 AT hook, DNA binding motif, containing 1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANKRD26 ankyrin repeat domain 26
ANKRD52 ankyrin repeat domain 52
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ASXL1 additional sex combs like transcriptional regulator 1
ATG4C autophagy related 4C, cysteine peptidase
ATXN2L ataxin 2-like
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCL9L B-cell CLL/lymphoma 9-like
BOD1L2 biorientation of chromosomes in cell division 1-like 2
BOP1 block of proliferation 1
BRAP BRCA1 associated protein
C19ORF57 chromosome 19 open reading frame 57
CABLES2 Cdk5 and Abl enzyme substrate 2
CABP4 calcium binding protein 4
CARS cysteinyl-tRNA synthetase
CBLN1 cerebellin 1 precursor
CD46 CD46 molecule, complement regulatory protein
CDK6 cyclin-dependent kinase 6
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CEP152 centrosomal protein 152kDa
CERCAM cerebral endothelial cell adhesion molecule
CHD6 chromodomain helicase DNA binding protein 6
CIC capicua transcriptional repressor
COL6A2 collagen, type VI, alpha 2
CRACR2B calcium release activated channel regulator 2B
CTC1 CTS telomere maintenance complex component 1
CTNND1 catenin (cadherin-associated protein), delta 1
CTTNBP2NL CTTNBP2 N-terminal like
CUL4A cullin 4A
CUL9 cullin 9
CWF19L2 CWF19-like 2, cell cycle control (S. pombe)
DAPK1 death-associated protein kinase 1
DDIT4 DNA-damage-inducible transcript 4
DMXL2 Dmx-like 2
DOK3 docking protein 3
DST dystonin
EFR3A EFR3 homolog A (S. cerevisiae)
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ETAA1 Ewing tumor-associated antigen 1
FAM161B family with sequence similarity 161, member B
FEN1 flap structure-specific endonuclease 1
FNBP1L formin binding protein 1-like
GBAS glioblastoma amplified sequence
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GBP1 guanylate binding protein 1, interferon-inducible
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HSBP1 heat shock factor binding protein 1
IGSF9B immunoglobulin superfamily, member 9B
ITSN1 intersectin 1 (SH3 domain protein)
JDP2 Jun dimerization protein 2
JMJD8 jumonji domain containing 8
KCTD1 potassium channel tetramerization domain containing 1
KDM5A lysine (K)-specific demethylase 5A
KIF20A kinesin family member 20A
KIF22 kinesin family member 22
KRAS Kirsten rat sarcoma viral oncogene homolog
LEPROTL1 leptin receptor overlapping transcript-like 1
LMBRD2 LMBR1 domain containing 2
LMLN leishmanolysin-like (metallopeptidase M8 family)
LRP5 low density lipoprotein receptor-related protein 5
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBD6 methyl-CpG binding domain protein 6
MCAM melanoma cell adhesion molecule
MPPE1 metallophosphoesterase 1
NBEAL2 neurobeachin-like 2
NME7 NME/NM23 family member 7
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae)
NUMBL numb homolog (Drosophila)-like
PARD6G par-6 family cell polarity regulator gamma
PCBP2 poly(rC) binding protein 2
PCNXL2 pecanex-like 2 (Drosophila)
PEX13 peroxisomal biogenesis factor 13
PHIP pleckstrin homology domain interacting protein
PLCE1 phospholipase C, epsilon 1
PLEC plectin
PLXNB2 plexin B2
PNPLA2 patatin-like phospholipase domain containing 2
PPAP2C phosphatidic acid phosphatase type 2C
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP4C protein phosphatase 4, catalytic subunit
PRG4 proteoglycan 4
RABGAP1L RAB GTPase activating protein 1-like
RAI14 retinoic acid induced 14
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RAVER2 ribonucleoprotein, PTB-binding 2
RB1CC1 RB1-inducible coiled-coil 1
RBL1 retinoblastoma-like 1
RC3H1 ring finger and CCCH-type domains 1
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RGCC regulator of cell cycle
RIN3 Ras and Rab interactor 3
RNF145 ring finger protein 145
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SERINC5 serine incorporator 5
SIX5 SIX homeobox 5
SLC38A10 solute carrier family 38, member 10
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SMC4 structural maintenance of chromosomes 4
SNX15 sorting nexin 15
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
STAMBPL1 STAM binding protein-like 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TFRC transferrin receptor
TNRC6A trinucleotide repeat containing 6A
TOP2A topoisomerase (DNA) II alpha 170kDa
TRIP10 thyroid hormone receptor interactor 10
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSC2 tuberous sclerosis 2
TTC28 tetratricopeptide repeat domain 28
TUFT1 tuftelin 1
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP53 ubiquitin specific peptidase 53
WDR19 WD repeat domain 19
ZFPM1 zinc finger protein, FOG family member 1
ZIK1 zinc finger protein interacting with K protein 1
ZMYM5 zinc finger, MYM-type 5
ZNF112 zinc finger protein 112
ZNF48 zinc finger protein 48
ZNF579 zinc finger protein 579
ZNF598 zinc finger protein 598
ZNF616 zinc finger protein 616
ZNF786 zinc finger protein 786
ZNHIT2 zinc finger, HIT-type containing 2
ZXDB zinc finger, X-linked, duplicated B