Optic Neuritis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An optic nerve disease that results_in inflammation located_in optic nerve which may cause a complete or partial loss of vision. (Human Disease Ontology, DOID_1210)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D009902
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Genes

16 genes/proteins associated with the disease Optic Neuritis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.23899
CAT catalase 1.23042
TNF tumor necrosis factor 1.19966
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.16799
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.15223
IL6 interleukin 6 1.12872
RHPN2 rhophilin, Rho GTPase binding protein 2 1.11639
SOD2 superoxide dismutase 2, mitochondrial 1.08126
PARP1 poly (ADP-ribose) polymerase 1 1.07696
TAGLN transgelin 1.06588
CTSL cathepsin L 1.06297
PRL prolactin 1.052
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.04427
CCL2 chemokine (C-C motif) ligand 2 1.03046
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.0241
KRT8 keratin 8, type II 1.01663