Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways Gene Set

Dataset Reactome Pathways
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-168643
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Genes

47 proteins participating in the Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways pathway from the Reactome Pathways dataset.

Symbol Name
AIM2 absent in melanoma 2
APP amyloid beta (A4) precursor protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
CARD9 caspase recruitment domain family, member 9
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CHUK conserved helix-loop-helix ubiquitous kinase
CYLD cylindromatosis (turban tumor syndrome)
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
ITCH itchy E3 ubiquitin protein ligase
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MEFV Mediterranean fever
NLRC4 NLR family, CARD domain containing 4
NLRP1 NLR family, pyrin domain containing 1
NLRP3 NLR family, pyrin domain containing 3
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PANX1 pannexin 1
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PYCARD PYD and CARD domain containing
RIPK2 receptor-interacting serine-threonine kinase 2
SUGT1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TXN thioredoxin
TXNIP thioredoxin interacting protein
UBE2N ubiquitin-conjugating enzyme E2N
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1